Microcystin-LR induces fatty liver metabolic disease in zebrafish through the PPARα-NOD1 pathway: In vivo, in vitro, and in silico investigations DOI

Kang Ou-Yang,

Ya He,

Hui Yang

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 485, P. 136813 - 136813

Published: Dec. 7, 2024

Language: Английский

Spatiotemporal dynamics of microcystin contamination in fish across the Lake Chaohu basin under the Yangtze River ten-year fishing ban: Ecological and human health implications DOI

Shengpan Han,

Wulai Xia,

Jun He

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 296, P. 118185 - 118185

Published: April 12, 2025

Language: Английский

Citations

0
Nanoconfinement Effect and Nanozyme Catalysis Enhance ILu/HOF-14 Electrochemiluminescence for Biosensing DOI
Qianqian Cai, Yuehui Wang,

Guifen Jie

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 12, 2025

A low collision frequency and an insufficient number of free radicals are the main problems leading to electroluminescence (ECL) efficiency luminol its derivatives. In order solve above issues, this work used nanoconfinement combined with nanozyme catalysis significantly enhance ECL efficiency. We assembled isoluminol (ILu) into hydrogen-bonded organic framework HOF-14 prepared a novel emitter ILu/HOF-14 for first time. Surprisingly, compared ILu/H2O2 system, signal ILu/HOF-14/H2O2 was increased by 33 times. This because porous structure effectively limited movement their frequency. Therefore, reaction rate between improved achieve amplification. To further increase radicals, we introduced hybrid Zn SAC@CuO2 NPs superior peroxidase (POD)-like activity. It could catalyze coreactant H2O2 produce large amount ROS (OH• O2•-), accelerating ILu improving signal. Based on research, dual-mode biosensing imaging platform constructed detect microcystin-LR (MC-LR). nonspecific trans-cleavage activity CRISPR-Cas12a system dynamic continuity amplification capability platform, detection sensitivity broadening avenues molecular diagnostic strategies.

Language: Английский

Citations

0
Investigation of the structural changes in the hippocampus and prefrontal cortex using FTIR spectroscopy in sleep deprived mice DOI
Devrim Sarıbal,

Hakan Çalis,

Zeynep Ceylan

et al.

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Journal Year: 2024, Volume and Issue: 321, P. 124702 - 124702

Published: June 21, 2024

Language: Английский

Citations

2
Introducing fluorescent probe technology for detecting microcystin-LR in the water and cells DOI
Bingyan Li, Zhaomin Wang,

Huiyan Chuan

et al.

Analytica Chimica Acta, Journal Year: 2023, Volume and Issue: 1288, P. 342188 - 342188

Published: Dec. 29, 2023

Language: Английский

Citations

3
Adverse outcome pathway of Alzheimer’s Disease-like changes resulting from autophagy flux blockade after MC-LR exposure DOI
Yuhan Ma, Dihui Xu,

Yibin Gan

et al.

Environmental Pollution, Journal Year: 2024, Volume and Issue: 364, P. 125322 - 125322

Published: Nov. 15, 2024

Language: Английский

Citations

0
Microcystin-LR induces fatty liver metabolic disease in zebrafish through the PPARα-NOD1 pathway: In vivo, in vitro, and in silico investigations DOI

Kang Ou-Yang,

Ya He,

Hui Yang

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 485, P. 136813 - 136813

Published: Dec. 7, 2024

Language: Английский

Citations

0