Brominated Flame Retardants Exposure Promotes the Formation of Atherosclerotic Plaque in Aortic Roots of ApoE^–/– Mice by Increasing Macrophage Recruitment and Foam Cell Formation

Environment & Health, Journal Year: 2025, Volume and Issue: unknown

Published: March 12, 2025

Language: Английский

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Unraveling the pervasive influence of brominated flame retardants on reproductive and developmental outcomes: A systematic review

Environmental Chemistry and Ecotoxicology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

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Occupational Exposure to Pesticides Among Farmworkers in Morocco: A Study Framework for Endocrine and Epigenetic Effect Assessment

Toxics, Journal Year: 2025, Volume and Issue: 13(5), P. 340 - 340

Published: April 25, 2025

Pesticides are compounds of major use in agriculture worldwide. Nevertheless, many pesticide chemicals classified as endocrine disruptors and potentially carcinogens. Farmers farmworkers particularly exposed at high risk developing health-related impairments. In Morocco, the lack awareness towards hazards inappropriate application safety measures might increase exposure well risks health concerns. this paper, we present framework a study designed to assess among Moroccan farmers evaluate potential effects, namely epigenetic impacts. Human biological monitoring will be conducted determine levels urine following development validation sensitive chromatography methods (SPE, UPLC-MS/MS). Biomarkers include set parent metabolite (organophosphates, pyrethroids, triazines urea-based pesticides). Thyroid reproductive hormones (TSH, T3, T4, FSH LH) global specific DNA methylation markers (5-mC, 5-hmC, N6-mA, THRB LHR) selected biomarkers effects. This provides guiding steps perform reliable evaluation impact assessment. aims expand current knowledge on related pesticides, especially low- middle-income countries.

Language: Английский

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Presence of hazardous chemical elements in low-cost children's toys: A risk to their development in early childhood

Journal of King Saud University - Science, Journal Year: 2024, Volume and Issue: 36(6), P. 103206 - 103206

Published: April 9, 2024

The objectives of the current study was to presence hazardous chemical elements (Ba138, Cd111, Cr52, Pb208, As75, Co59, Cu63, Mn55, Ni60, Se82, Sr88, Zn66 and Hg202) in low-cost children's toys, effect color types on element concentrations Children's toy samples were analyzed using microwave digestion inductively coupled plasma/mass spectrometry (ICP/MS) method. Samples prepared into small pieces, 500 mg homogenized sample used for by means digesting regents HNO3 (65 %, 5 mL) H2O2 (35 1 mL). During process, pressure held constant at 90 bar temperature, hold time, power varied 150–170-40° C, 10–30-5 min, 70–90-0 respectively. main operating conditions ICP/MS were: spray chamber temperature (−20 °C), RF Power (1450 W), nebulizer gas flow (0.9 L/min), auxiliary (0.8 L/min) plasma (14.85 L/min). blanks 30 s system operated standard mode. excellent method performance achieved terms limit detection (LOD, 0.001–14.89 µg/L); quantification (LOQ, 0.003–45.12 correlation coefficient (R2, 0.975–0.999) with relative deviation values (RSD, 0.70–4.98 %). Chemical found all toys (0.01–742.72 ng/g) except S2 where only Hg202 (0.01 ng/g). Outcomes revealed that present a very low level while high levels (742.72 Furthermore, contamination also be color-specific, significant amounts black type car (S5, 946.98 whereas other constitutes lower (0.001–210.53 Low-cost designed use are contain should addressed course action. As result exposure children have chance developing cancer.

Language: Английский

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Unraveling the genetic and epigenetic landscape governing intramuscular fat deposition in rabbits: Insights and implications

Food Chemistry Molecular Sciences, Journal Year: 2024, Volume and Issue: 9, P. 100222 - 100222

Published: Aug. 30, 2024

Language: Английский

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