Ecotoxicology and Environmental Safety,
Journal Year:
2025,
Volume and Issue:
291, P. 117883 - 117883
Published: Feb. 1, 2025
Microplastics
(MPs)
are
emerging
contaminants
characterized
by
persistence,
cross-media
transport,
and
complex
pollutant
interactions,
posing
serious
ecotoxicological
risks
to
ecosystems
human
health.
Effective
MPs
management
requires
multi-faced,
long-term,
strategies
involving
targeted
sampling,
quantitative
detection,
comprehensive
risk
assessments,
all
of
which
entail
significant
resource
investment.
Despite
advancements
in
remediation
technologies,
a
holistic
governance
framework
integrating
these
innovations
remains
underdeveloped.
This
review
synthesizes
current
knowledge
on
MPs,
elaborating
their
diverse
morphologies,
degradation
pathways,
role
as
vectors
for
toxic
substances.
State-of-the-art
extraction
techniques
evaluated
this
article,
including
micropore
adsorption
using
nanocomposites,
alongside
the
incorporation
advanced
analytical
tools
such
spectroscopic
methods,
electron
microscopy,
bioinformatics
augment
environmental
forensics.
also
underscores
necessity
formulating
robust
global
policies
regulate
pollution
discusses
potential
biodegradation
thermal
sustainable
solutions
removal.
By
promoting
an
interdisciplinary
approach,
advocates
coordinated
response,
science,
policy
frameworks,
waste
mitigate
escalating
impact
well-being.
Toxics,
Journal Year:
2024,
Volume and Issue:
12(6), P. 420 - 420
Published: June 7, 2024
Transgenerational
nanoplastic
toxicity
could
be
detected
in
Caenorhabditis
elegans
after
exposure
at
the
parental
generation
(P0-G);
however,
underlying
mechanisms
remain
largely
unclear.
We
aimed
to
examine
role
of
germline
nuclear
hormone
receptors
(NHRs)
controlling
transgenerational
polystyrene
nanoparticles
(PS-NPs)
based
on
gene
expression
screening
and
functional
analysis.
Among
NHR
genes,
daf-12,
nhr-14,
nhr-47
expressions
were
increased
nhr-12
was
decreased
by
PS-NPs
(1
10
μg/L).
alterations
these
four
genes
also
induced
RNAi
caused
resistance,
whereas
conferred
susceptibility
PS-NP
toxicity.
After
exposure,
ins-3,
daf-28,
ins-39
encoding
insulin
ligands,
efn-3
Ephrin
ligand,
lin-44
Wnt
as
well
their
receptor
(daf-2,
vab-1,
and/or
mig-1),
dysregulated
nhr-47,
nhr-12.
Therefore,
alteration
certain
NHRs
mediate
induction
affecting
secreted
ligands
offspring
exposed
organisms.
Toxics,
Journal Year:
2024,
Volume and Issue:
12(3), P. 178 - 178
Published: Feb. 26, 2024
The
escalating
prevalence
of
microplastics
and
nanoplastics
in
aquatic
environments
is
a
major
challenge
affecting
the
behavior
reproductive
health
organisms
while
posing
potential
risks
to
human
ecosystems.
This
review
focuses
on
neurobehavioral
changes
toxicity
MNPs
zebrafish
their
relationships.
At
same
time,
caused
by
were
studied,
synergistic
effects
interaction
these
pollutants
with
other
environmental
contaminants
explored.
In
addition,
zebrafish,
as
model
organism,
provide
valuable
insights
into
subtle
but
important
behavior,
which
critical
for
understanding
success,
suggesting
that
behavioral
can
serve
an
early
biomarker
toxicity.
based
classical
endocrine
disruptor
models
research
methods,
current
status
was
reviewed,
further
indicated
parameters
be
used
effective
rapid
tool
evaluate
MNPs.
However,
methods
rapidly
assessing
are
still
area
exploration.
To
address
limitations
challenges
scope
research,
this
outlines
future
directions
aim
improving
our
impacts
work
aims
inform
targeted
policies
advance
public
strategies
growing
pollution.
Toxics,
Journal Year:
2024,
Volume and Issue:
12(8), P. 555 - 555
Published: July 30, 2024
Increasing
evidence
has
suggested
that
nanoplastic
pollution
become
a
global
concern.
More
importantly,
transgenerational
toxicity
can
be
induced
by
nanoplastics
at
predicted
environmentally
relevant
doses
(ERDs).
Considering
amino
modification
could
increase
toxicity,
we
compared
neurotoxicity
between
pristine
polystyrene
nanoparticle
(PS-NP)
and
amino-modified
PS-NP
(NH
