Polystyrene Nanomicroplastics Aggravate Ammonia-Induced Neurotoxic Effects in Zebrafish Embryos DOI Creative Commons

Dan Xing,

Wenting Zheng,

Zhou Hui-ming

et al.

Toxics, Journal Year: 2024, Volume and Issue: 12(12), P. 853 - 853

Published: Nov. 26, 2024

The highly hazardous chemical ammonia has been proven to be absorbed by nanoparticles, thereby exerting toxic effects on aquatic organisms. As a ubiquitous pollutant in environments, polystyrene nanomicroplastics (PSNPs) have shown strong adsorption capacity due their large surface area. Therefore, the potential joint of and PSNPs need clarified. In this study, zebrafish embryos were exposed water solution with concentrations (0, 0.1, 1, 10 mg/L) or without PSNP (100 μg/L) treatment up 120 hpf. results showed that combined exposure increased accumulation obviously reduced locomotor speed larvae compared alone. Further studies indicated can aggravate ammonia-induced neurotoxicity altering cholinergic system, dopaminergic neurons, retinal structure larvae. addition, our revealed caused significant alterations expression genes related neurodevelopment development, exacerbated adverse effect. conclusion, early stage associated health risk animals should not underestimated. main contribution article lies revealing synergistic zebrafish. Moreover; it emphasizes risks

Language: Английский

Female zebrafish are more affected than males under polystyrene microplastics exposure DOI
Di Wu,

Laura Carter,

Paul Kay

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 482, P. 136616 - 136616

Published: Nov. 21, 2024

Language: Английский

Citations

1
Size-dependent dynamics and tissue-specific distribution of nano-plastics in Danio rerio: Accumulation and depuration DOI
Théogène Habumugisha,

Zixing Zhang,

Changzhou Yan

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 484, P. 136775 - 136775

Published: Dec. 4, 2024

Language: Английский

Citations

1
Polystyrene Nanomicroplastics Aggravate Ammonia-Induced Neurotoxic Effects in Zebrafish Embryos DOI Creative Commons

Dan Xing,

Wenting Zheng,

Zhou Hui-ming

et al.

Toxics, Journal Year: 2024, Volume and Issue: 12(12), P. 853 - 853

Published: Nov. 26, 2024

The highly hazardous chemical ammonia has been proven to be absorbed by nanoparticles, thereby exerting toxic effects on aquatic organisms. As a ubiquitous pollutant in environments, polystyrene nanomicroplastics (PSNPs) have shown strong adsorption capacity due their large surface area. Therefore, the potential joint of and PSNPs need clarified. In this study, zebrafish embryos were exposed water solution with concentrations (0, 0.1, 1, 10 mg/L) or without PSNP (100 μg/L) treatment up 120 hpf. results showed that combined exposure increased accumulation obviously reduced locomotor speed larvae compared alone. Further studies indicated can aggravate ammonia-induced neurotoxicity altering cholinergic system, dopaminergic neurons, retinal structure larvae. addition, our revealed caused significant alterations expression genes related neurodevelopment development, exacerbated adverse effect. conclusion, early stage associated health risk animals should not underestimated. main contribution article lies revealing synergistic zebrafish. Moreover; it emphasizes risks

Language: Английский

Citations

0