PFHxA and PFHxS promote breast cancer progression in 3D culture: MEX3C-associated immune infiltration revealed by bioinformatics and machine learning DOI
Huan Wang,

Guangming Xie,

Zhijin Zhang

et al.

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 494, P. 138458 - 138458

Published: May 2, 2025

Language: Английский

Global Burden and Trend of Thyroid Cancer in Children and Adolescents Aged 0 – 19 Years: A Systematic Analysis of the Global Burden of Diseases Study 1990 – 2021 DOI

Wenyi Zhang,

Jiabei He,

Weiqiong Jin

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
Emerging Potential of Metabolomics in Thyroid Cancer—A Comprehensive Review DOI Open Access
Sonam Kumari,

Andrew Makarewicz,

Joanna Kłubo-Gwieździńska

et al.

Cancers, Journal Year: 2025, Volume and Issue: 17(6), P. 1017 - 1017

Published: March 18, 2025

Thyroid cancer is a very common endocrine system malignancy. Nevertheless, dearth of precise markers makes it challenging to apply precision medicine thyroid cancer. The limitations standard diagnosis techniques (fine-needle aspiration biopsy), such as indeterminate cases and inaccuracies in distinguishing between different types cancers, lead unnecessary surgeries thus warrant the development more discriminatory biomarkers improve accuracy existing diagnostic prognostic techniques. Moreover, individualized therapies for are necessary avoid overtreatment indolent lesions undertreatment high-risk progressive disease. As metabolic signatures associated with disease aggressiveness responsiveness therapy, metabolomics has been recently used biomarker discovery. This strategy enabled detection several metabolites from tissue samples or biofluids facilitate classification potentially assist therapies. In this review, we summarize utilization potential

Language: Английский

Citations

0
Health Impacts of Per- and Polyfluoroalkyl Substances (PFASs): A Comprehensive Review DOI Creative Commons
Csilla Mišľanová, Martina Valachovičová

Life, Journal Year: 2025, Volume and Issue: 15(4), P. 573 - 573

Published: April 1, 2025

Per- and polyfluoroalkyl substances (PFASs) are among the persistent organic pollutants characterized by their persistence in environment, high mobility, adverse impact not only on ecosystem but also human health. The biggest challenges biomonitoring low concentrations of PFASs biological matrices presence matrix interferents samples. combination liquid chromatography with tandem mass spectrometry (LC-MS/MS) solid-phase extraction (SPE) as a sample preparation technique appears to be most suitable solution for achieving desired selectivity sensitivity PFAS determination. aim this review is describe possible sources PFASs, various matrices, analytical methods determining different using pretreatment techniques complex samples, well health risks associated exposure. studied include PFOA PFOS, which frequently detected such plasma, serum, breast milk. average range from 1.0 2.6 ng.mL−1 1.9 2.4 0.4 3.1 For were 2.0–4.0 ng.mL−1, 3.7–4.6 3.6–4.8 milk, respectively. significant effects exposure long-chain (such PFOS) lipid disorders, hypertension, diabetes mellitus, thyroid infertility, cancer, obesity, autism, neurodevelopmental issues, cardiovascular diseases, kidney liver disorders. It utmost importance monitor exposure, predict toxicity, develop effective strategies mitigate potential

Language: Английский

Citations

0
PFHxA and PFHxS promote breast cancer progression in 3D culture: MEX3C-associated immune infiltration revealed by bioinformatics and machine learning DOI
Huan Wang,

Guangming Xie,

Zhijin Zhang

et al.

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 494, P. 138458 - 138458

Published: May 2, 2025

Language: Английский

Citations

0