bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 10, 2024
ABSTRACT
Pharmaceuticals
are
recognised
among
emerging
contaminants,
particularly
in
water.
They
have
the
potential
to
alter
ecosystem
dynamics,
with
notable
examples
including
hormone-induced
feminization
of
male
fish
and
disruptions
oogenesis
invertebrates.
To
assess
risk
posed
by
pharmaceuticals,
it
is
essential
understand
their
amount
(via
Measured
Environmental
Concentrations
–
MEC)
actual
effects
on
target
species
Predicted
No
Effect
PNEC).
Recently,
many
studies
aimed
collect
MEC
data
from
around
world,
but
a
comprehensive
overview
still
lacking.
Thus,
objective
this
study
provide
examining
recently
published
literature
for
wide
range
pharmaceuticals.
Additionally,
enable
assessment,
also
reviewed
PNEC
integrated
existing
databases.
A
total
315
substances
were
selected
extraction,
inclusion
56
articles.
The
most
frequently
monitored
locations
Cadiz
Bay
Spain
(90
samples),
River
Thames
UK
(51),
Hrdějovice
Czech
Republic
(49).
Most
samples
collected
surface
water
(N=325),
influent
wastewater
treatment
plants
(WWTP)
(205),
effluent
WWTP
(118).
Based
values,
analysis
identified
81
pharmaceuticals
as
high-risk,
highest
values
propranolol
(risk
quotient
[RQ]:
29,450,000),
diclofenac
(395,920),
17alpha-ethinylestradiol
(95,946).
ATC
classes
high-risk
anti-infectives
(J),
nervous
system
agents
(N),
cardiovascular
(C),
antineoplastic
(L),
analgesics
(M),
sex
hormones
(G).
findings
highlight
widespread
impact
across
globe
involvement
multiple
therapeutic
classes.
move
beyond
current
point-in-time
overview,
which
limited
specific
sampling
periods,
systems
continuous
monitoring
should
be
developed.
This
could
involve
creation
resource-efficient
methods
integration
estimation
models.
Furthermore,
these
results
serve
starting
point
developing
implementing
actions
prevent
mitigate
environmental
Environmental Pollution,
Journal Year:
2024,
Volume and Issue:
356, P. 124205 - 124205
Published: May 24, 2024
Global
usage
of
pharmaceuticals
has
led
to
the
proliferation
bacteria
that
are
resistant
antimicrobial
treatments,
creating
a
substantial
public
health
challenge.
Here,
we
investigate
emergence
sulfonamide
resistance
genes
in
groundwater
and
surface
water
Patna,
rapidly
developing
city
Bihar,
India.
We
report
first
quantification
three
(sulI,
sulII
sulIII)
(12-107
m
depth)
The
mean
relative
abundance
gene
copies
was
found
be
sulI
(2.4
×
10
IWA Publishing eBooks,
Journal Year:
2024,
Volume and Issue:
unknown
Published: April 12, 2024
Abstract
Detection
and
Treatment
of
Emerging
Contaminants
in
Wastewater
addresses
the
critical
pressing
need
for
effective
strategies
to
detect
treat
emerging
contaminants,
thereby
mitigating
risks
associated
with
their
presence
wastewater.
This
comprehensive
book
features
contributions
from
prominent
experts
field
wastewater,
providing
an
up-to-date
in-depth
collection
chapters
dedicated
tackling
this
issue.
Highlights:
The
serves
as
invaluable
resource
identifying,
assessing,
comprehensively
addressing
contaminants
wastewater
and/or
sludges.
It
delves
into
assessment,
mitigation,
treatment
various
including
microplastics,
antibiotic-resistant
genes,
pharmaceuticals,
personal
care
products
industrial
chemicals.An
exploration
behavior
microplastics
different
plants
accumulation
sludge,
shedding
light
on
potential
impact
environment.An
introduction
key
mechanisms
removal
pollutants
sludge
through
fungal-mediated
processes,
offering
innovative
solutions
treatment.An
investigation
fate
pharmaceutically-active
compounds
along
environmental
impacts.
Additionally,
accurate
quantification
procedures
these
are
discussed.The
covers
new
trends
development
greener
nanomaterials,
evaluating
performance
abating
With
its
insights
diverse
perspectives,
is
essential
guide
researchers,
professionals,
policymakers
engaged
management
protection.
practical
scientific
knowledge
presented
herein
will
contribute
significantly
safeguarding
our
water
resources
ensuring
a
cleaner
healthier
future.
ISBN:
9781789063745
(paperback)
9781789063752
(ebook)
(ePub)
Water Research,
Journal Year:
2025,
Volume and Issue:
278, P. 123374 - 123374
Published: Feb. 25, 2025
The
Ganga
River
(known
internationally
as
the
Ganges)
is
one
of
world's
most
prominent
rivers,
running
from
Himalayas
to
Bay
Bengal
and
supporting
livelihoods
>
40
%
India's
1.4
billion
population.
regionally
globally
important,
agriculture
industry,
yet
faces
potentially
detrimental
water
quality
challenges
arising
runoff
discharge
increasing
urbanization,
industry
agriculture.
A
∼
2700
km
longitudinal
survey
nutrient
microbial
quality,
including
phytoplankton
composition,
was
undertaken
in
November
2019.
aim
investigate
if
how
anthropogenic
activities
(e.g.
urbanisation,
agriculture)
tributary
convergence
(potentially
reflecting
both
human
activity
flow
influences)
affect
shift
physicochemical,
nutrient,
parameters
along
river
continuum.
Segmented
regression
identified
four
zones
distinct
nutrient/microbial
characteristics
River,
with
breakpoints
located
near
Kanpur,
Varanasi
downstream
Farakka
Barage,
at
distances
1020,
1500
2350
Himalayan
source.
Population
density,
land
use
urban
cover
were
associated
selected
parts
catchment,
elevated
chemical
concentrations
likely
agriculture,
sewage
inputs.
Some
areas
Kanpur
Varanasi),
converging
tributaries
Yamuna
Varuna)
barrages
Farakka)
changes
availability,
activity/abundance
modelled
discharge,
driving
apparent
relevant
locations.
Downstream
shifts
observed
throughout
This
information
can
help
prioritize
locations
for
targeted
monitoring
and/or
remediation
interventions
has
illustrated
an
approach
quantify
impacts
inputs
on
major
systems,
such
River.
