The repairing effect of baicalein on lead induced damage to the gut-liver axis in tadpoles

Environmental Pollution, Journal Year: 2025, Volume and Issue: unknown, P. 126232 - 126232

Published: April 1, 2025

Language: Английский

The Opposite Effects of Atrazine and Warming on the Reproductive Processes in Female Lizards (Eremias argus): Potential Roles of Hypothalamic–Pituitary–Gonadal Axis Regulation and Energy Metabolism

Environmental Science & Technology, Journal Year: 2025, Volume and Issue: unknown

Published: May 7, 2025

Declines in reptile populations due to climate warming and environmental pollution have been documented. Although recent ecotoxicological studies of reptiles increased, little is known about how these two stressors interact affect reproductive processes. This study investigated the single combined effects atrazine on reproduction female lizards (Eremias argus) following 10 weeks exposure environmentally relevant concentrations (0-10 mg·kg-1) at temperature treatments (control or warming). Reproductive traits, clutch characteristics, endpoints related endocrine disruption (HPG axis gene expression) energy metabolism (enzyme activity, hepatic metabolomics) were assessed. Atrazine inhibits by disrupting HPG axis-related expression metabolism, resulting delayed spawning time reduced fecundity. In contrast, promoted partly alleviated inhibitory atrazine, which upregulation an additional compensatory response. Additionally, and/or altered direction intensity trade-off between egg number size affected maternal nutritional investment eggs. These findings highlight complex interplay lizard add a better understanding strategies ecological consequences under stress.

Language: Английский

Toxicity of Polystyrene Microplastics with Cadmium on the Digestive System of Rana zhenhaiensis Tadpoles

Toxics, Journal Year: 2024, Volume and Issue: 12(12), P. 854 - 854

Published: Nov. 26, 2024

Microplastics pollution in freshwater systems is attracting increasing attention. However, our knowledge of its combined toxicity with heavy metals scarce. In this study, Rana zhenhaiensis was used as the model animal to study poisoning mechanism cadmium or microplastics on digestive tadpoles freshwater. Results showed that exposure and polystyrene increased mortality metamorphosis rate R. tadpoles, delayed their growth development. Cadmium detected livers intestines, while mainly accumulated gills intestines tadpoles. The individual can cause pathological damage liver tissue, induce oxidative stress liver, change gene expression. co-exposure reduce accumulation liver. While slightly increase intestine. Exposure altered abundance community structure intestinal microbiota, dysregulation gut microbiome. had a negative impact but introduction needs further investigation, due different characteristics microplastics.

Language: Английский