A new method for the simultaneous determination of cyanotoxins (Microcystins and Cylindrospermopsin) in mussels using SPE-UPLC-MS/MS DOI
Leticia Díez-Quijada, Remedios Guzmán‐Guillén, Giorgiana M. Cătunescu

et al.

Environmental Research, Journal Year: 2020, Volume and Issue: 185, P. 109284 - 109284

Published: Feb. 21, 2020

Language: Английский

Comprehensive insights into the occurrence and toxicological issues of nodularins DOI
Guoliang Chen, Linping Wang, Mingxing Wang

et al.

Marine Pollution Bulletin, Journal Year: 2020, Volume and Issue: 162, P. 111884 - 111884

Published: Dec. 9, 2020

Language: Английский

Citations

30
Ultra-sensitive detection of microcystin-LR with a new dual-mode aptasensor based on MoS2-PtPd and ZIF-8-Thi-Au DOI
Jiahao Wu, Chao Yu, Yujie Yu

et al.

Sensors and Actuators B Chemical, Journal Year: 2019, Volume and Issue: 305, P. 127280 - 127280

Published: Oct. 21, 2019

Language: Английский

Citations

27
Cylindrospermopsin-Microcystin-LR Combinations May Induce Genotoxic and Histopathological Damage in Rats DOI Creative Commons
Leticia Díez-Quijada, Concepción Medrano‐Padial, María Llana‐Ruíz‐Cabello

et al.

Toxins, Journal Year: 2020, Volume and Issue: 12(6), P. 348 - 348

Published: May 26, 2020

Cylindrospermopsin (CYN) and microcystins (MC) are cyanotoxins that can occur simultaneously in contaminated water food. CYN/MC-LR mixtures previously investigated vitro showed an induction of micronucleus (MN) formation only the presence metabolic fraction S9. When this is case, European Food Safety Authority recommends a follow up to vivo testing. Thus, rats were orally exposed 7.5 + 75, 23.7 237, 75 750 μg CYN/MC-LR/kg body weight (b.w.). The MN test bone marrow was performed, standard modified comet assays carried out measure DNA strand breaks or oxidative damage stomach, liver, blood cells. results revealed increase marrow, at all assayed doses. However, no nor induced, as shown assays. histopathological study indicated alterations highest dose group. Liver target organ showing fatty degeneration necrotic hepatocytes centrilobular areas, well light mononuclear inflammatory periportal infiltrate. Additionally, stomach had flaking epithelium mild necrosis epithelial Therefore, combined exposure may induce genotoxic vivo.

Language: Английский

Citations

26
Distribution of microcystins in environmental multimedia and their bioaccumulation characteristics in marine benthic organisms in the Geum River Estuary, South Korea DOI
Mungi Kim, Dokyun Kim, Jaeseong Kim

et al.

The Science of The Total Environment, Journal Year: 2020, Volume and Issue: 757, P. 143815 - 143815

Published: Nov. 18, 2020

Language: Английский

Citations

25
A new method for the simultaneous determination of cyanotoxins (Microcystins and Cylindrospermopsin) in mussels using SPE-UPLC-MS/MS DOI
Leticia Díez-Quijada, Remedios Guzmán‐Guillén, Giorgiana M. Cătunescu

et al.

Environmental Research, Journal Year: 2020, Volume and Issue: 185, P. 109284 - 109284

Published: Feb. 21, 2020

Language: Английский

Citations

24