How will severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) and lead (Pb) exposure interact in the cardiovascular system? DOI Open Access
Emmanuel Obeng-Gyasi

Authorea (Authorea), Journal Year: 2023, Volume and Issue: unknown

Published: Sept. 19, 2023

The combined effects of lead exposure and the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) how they cause cardiovascular dysfunction are examined in this viewpoint manuscript.Lead was picked as a representative environmental contaminant because it has been studied extensively for more than 40 years, while SARS-CoV-2 illustrates unpredictability new infectious agent that can quickly increase burden on communities.Given interaction represents plausible many people, is crucial to discuss might happen at mechanistic level.SARS-CoV-2 causes coronavirus disease 2019 (COVID-19), which spread by contact droplets.One may be exposed simultaneously depending their living situation.Uncertainty exists regarding consequences its underlying processes.This paper aims investigate these mechanisms provide potential behind them.The with system likely caused direct damage, promotion reactive oxygen species (ROS) production, oxidative stress, inflammation.In particular, stimulation nuclear factor kappa B (NF-B), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF) were all identified potentially important pathways.Blood clotting, cytokine storm cycle development, increased hypoxia also results this.In summary, immune system, coagulation, renin-angiotensin-aldosterone cardiac contractility four primary areas identified.

Language: Английский

Biomonitoring of Serum Inorganic Element Concentrations in Morbidly Obese Patients: Impact of Bariatric Surgery DOI Creative Commons
Álvaro Ramos-Luzardo, Pilar F. Valerón, Beatriz Vanessa Díaz-González

et al.

Toxics, Journal Year: 2025, Volume and Issue: 13(3), P. 152 - 152

Published: Feb. 23, 2025

Adipose tissue, in addition to serving as energy storage, can store lipophilic substances, some of which may pose a health risk if massively mobilized during rapid weight loss. This study aimed biomonitor inorganic elements obese patients undergoing bariatric surgery and analyze the role sociodemographic factors. ICP-MS was employed quantify 55 elements, including identified from ATSDR’s Substance Priority List rare-earth serum samples 58 before after surgery. A total 39 out were detected, either or surgery, at least one patient. Serum concentrations gold, copper, mercury, platinum, selenium significantly decreased iron zinc lower Age, sex, diabetes status, arterial hypertension, family history obesity demographic factors associated with concentration elements. Correlation analyses showed significant associations between lipid body mass index. Our findings indicate complex interplay fat provide relevant information regarding biomonitoring these chemical specific understudied population.

Language: Английский

Citations

0
Blood concentrations of metals, essential trace elements, rare earth elements and other chemicals in the general adult population of Barcelona: Distribution and associated sociodemographic factors DOI
Magda Gasull,

Judit Camargo,

José Pumarega

et al.

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 909, P. 168502 - 168502

Published: Nov. 15, 2023

Language: Английский

Citations

7
From old pollutants to the regulation of bisphenol A: Lessons learned for health promotion and disease prevention DOI
Vicente Mustieles,

Juan-Pedro Arrebola,

Miquel Porta

et al.

Preventive Medicine, Journal Year: 2023, Volume and Issue: 169, P. 107460 - 107460

Published: Feb. 20, 2023

Language: Английский

Citations

6
Human biomonitoring of inorganic elements in a representative sample of the general population from Cape Verde: Results from the PERVEMAC-II study DOI Creative Commons
Luis Alberto Henríquez‐Hernández, Manuel Zumbado, Ángel Rodríguez-Hernández

et al.

Chemosphere, Journal Year: 2023, Volume and Issue: 339, P. 139594 - 139594

Published: July 20, 2023

Inorganic elements such as heavy metals and other potentially toxic are frequently detected in humans. The aim of the present study was to analyze blood concentrations 49 inorganic a cohort 401 subjects from Cape Verde. performed frame Pesticide Residues Vegetables Macaronesia project (PERVEMAC-II). Concentration elements, including ATSDR's priority pollutant list rare earth (RREs) were measured by ICP-MS whole participants. A total 20 out (40.8%) ≥20% Arsenic, copper, mercury, lead, selenium, strontium zinc ≥99% samples. Among REEs, 7 showed detection frequencies above 20%. median number different 15. In series, 77.0, 99.2 33.4% participants values arsenic, mercury lead higher than Reference Values 95%. These percentages much those reported similar studies. Niobium tantalum highest concentrations: 1.35 1.34 ng/mL, suggesting an environmental source these valuable REEs Age appeared most important factor influencing levels elements. Lifestyle had effect on concentration some Those whose water pond significantly arsenic levels. ∑REEs among individuals who purchase their food supermarkets (P = 0.013). variables relevance since they can be controlled individually reduce exposure contaminants. Our results may useful for implementation public health measures competent authorities.

Language: Английский

Citations

5
Prepandemic personal concentrations of per- and polyfluoroalkyl substances (PFAS) and other pollutants: Specific and combined effects on the incidence of COVID-19 disease and SARS-CoV-2 infection DOI
José Pumarega, Magda Gasull, Jani Koponen

et al.

Environmental Research, Journal Year: 2023, Volume and Issue: 237, P. 116965 - 116965

Published: Aug. 29, 2023

Language: Английский

Citations

4
Microbial Inoculants and Their Potential Application in Bioremediation DOI

Shriniketan Puranik,

K. S. Sruthy,

M. Manoj

et al.

Published: July 12, 2024

An advancement in present-day science, especially the fields of technology, agriculture and allied sectors, has led to over-abuse a plethora chemical compounds. The chemicals are either naturally or anthropogenically released into surrounding matrices like water bodies, soil air, thereby severely contaminating them. Diverse properties these pollutants pose challenge their degradation using physical means. However, microorganisms have turned out be effective means for removal due assimilation detoxification potential contaminants as food sources. Using several enzymes, they also found convert poisonous forms less-toxic kinds, process called biotransformation. Furthermore, methods biostimulation genetic engineering increase bioremediation. While indigenous remediation involves biodegradation by stimulating localized microflora, exogenous method relies on inoculation potent externally site pollution. Ample bacteria, fungi, microalgae, etc., been discovered studied bioremediation capacity. They known employ many which help efficient defragmentation This chapter deals with such microbial inoculants enzymatic systems that aid some major pollutants.

Language: Английский

Citations

1
Aerobic bacterial degradation of polychlorinated biphenyls and their hydroxy and methoxy derivatives DOI
Т. И. Горбунова, Д. О. Егорова, В. И. Салоутин

et al.

Russian Chemical Reviews, Journal Year: 2024, Volume and Issue: 93(11), P. RCR5138 - RCR5138

Published: Oct. 30, 2024

Polychlorinated biphenyls are persistent organic pollutants hazardous to humans and the environment. The products of biotransformation these compounds can exist in natural objects as hydroxy methoxy derivatives. This review summarizes biodegradation pathways polychlorinated under action aerobic bacterial strains. possibility complete their derivatives laboratory conditions is demonstrated. information valuable for researchers specializing biotransformations toxicity polychloroarene would be useful development remediation processes contaminated with biphenyls.<br> bibliography includes 253 references.

Language: Английский

Citations

1
ORGANOPHOSPHATE PESTICIDE EXPOSURE AND RISK OF SARS-CoV-2 INFECTION DOI Creative Commons
Luis López, Katherine Kogut, Stephen Rauch

et al.

Environmental Research, Journal Year: 2024, Volume and Issue: 255, P. 119214 - 119214

Published: May 23, 2024

Several studies have reported immune modulation by organophosphate (OP) pesticides, but the relationship between OP exposure and SARS-CoV-2 infection is yet to be studied. We used two different measures of pesticide (urinary biomarkers (N = 154) residential proximity applications 292)) examine association early-childhood lifetime OPs risk using antibody data. Our study population consisted young adults (ages 18-21 years) from Center for Health Assessment Mothers Children Salinas (CHAMACOS) Study, a longitudinal cohort families California agricultural region. Urinary reflected in utero age 5 years. Residential exposures 16 antibodies blood samples collected June 2022 January 2023 were detected via enzyme linked immunosorbent assays, each designed bind antigens. performed logistic regression measure exposure, adjusting covariates demographic data self-reported questionnaire found increased odds among participants with higher urinary (OR 1.94, 95% CI: 0.71, 5,58) 0-5 1.90, 0.54, 6.95).

Language: Английский

Citations

0
Non-Occupational Exposure to Metal Elements in Finland – Urinary and Blood Biomonitoring Study DOI

Simo Porras,

Juha Tuovila,

Tiina Santonen

et al.

Published: Jan. 1, 2024

Language: Английский

Citations

0
How will severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) and lead (Pb) exposure interact in the cardiovascular system? DOI Open Access
Emmanuel Obeng-Gyasi

Authorea (Authorea), Journal Year: 2023, Volume and Issue: unknown

Published: Feb. 22, 2023

The combined effects of lead exposure and the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) how they cause cardiovascular dysfunction are examined in this viewpoint manuscript. Lead was picked as a representative environmental contaminant because it has been studied extensively for more than 40 years, while SARS-CoV-2 illustrates unpredictability new infectious agent that can quickly increase burden on communities. Given interaction represents plausible many people, is crucial to discuss might happen at mechanistic level. causes coronavirus disease 2019 (COVID-19), which spread by contact droplets. One may be exposed simultaneously depending their living situation. Uncertainty exists regarding consequences its underlying processes. This paper aims investigate these mechanisms provide potential behind them. with system likely caused direct damage, promotion reactive oxygen species (ROS) production, oxidative stress, inflammation. In particular, stimulation nuclear factor kappa B (NF-B), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF) were all identified potentially important pathways. Blood clotting, cytokine storm cycle development, increased hypoxia also results this. summary, immune system, coagulation, renin-angiotensin-aldosterone cardiac contractility four primary areas identified.

Language: Английский

Citations

0