Blood Concentrations of Metals, Essential Trace Elements, Rare Earth Elements and Other Chemicals in the General Adult Population of Barcelona: Distribution and Sociodemographic Predictors

Published: Jan. 1, 2023

A B S T R C TBackgroundVery little information is available on the population distribution and sociodemographic predictors of body concentrations rare earth elements (REE) other minority chemicals used in manufacturing high-tech devices.ObjectivesTo analyze determinants blood chemical (including some metals, essential trace elements, elements) a representative sample general Barcelona (Spain).MethodsParticipants Health Survey 2016 (N = 240) were interviewed face-to-face, gave blood, underwent physical exam. Concentrations 50 analyzed by ICP-MS whole samples.ResultsAll studied, including 26 REE detected. Lead, silver, arsenic, cadmium, mercury, antimony, strontium, thallium six detected more than 70% population. The most frequently were: europium (62%), thulium (56%), gold (41%), indium (31%), ruthenium (24%), tantalum (20%). Less affluent occupational social classes had higher percentages detection REE. Median cadmium mercury 0.091, 3.01, 0.309, 3.33 ng/mL, respectively. Women lower median men lead (1.47 vs. 2.04 µg/dL, respectively), iron zinc, copper manganese. influence characteristics differed gender.ConclusionsWhile well-known contaminants as lead, or majority population, numerous individuals also detectable emerging europium, indium, thulium, gold. There need to invest biomonitoring samples assess trends, sources health effects single pollutants mixtures related chemicals.

Language: Английский

How will severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) and lead (Pb) exposure interact in the cardiovascular system?

Authorea (Authorea), Journal Year: 2023, Volume and Issue: unknown

Published: Sept. 19, 2023

The combined effects of lead exposure and the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) how they cause cardiovascular dysfunction are examined in this viewpoint manuscript.Lead was picked as a representative environmental contaminant because it has been studied extensively for more than 40 years, while SARS-CoV-2 illustrates unpredictability new infectious agent that can quickly increase burden on communities.Given interaction represents plausible many people, is crucial to discuss might happen at mechanistic level.SARS-CoV-2 causes coronavirus disease 2019 (COVID-19), which spread by contact droplets.One may be exposed simultaneously depending their living situation.Uncertainty exists regarding consequences its underlying processes.This paper aims investigate these mechanisms provide potential behind them.The with system likely caused direct damage, promotion reactive oxygen species (ROS) production, oxidative stress, inflammation.In particular, stimulation nuclear factor kappa B (NF-B), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF) were all identified potentially important pathways.Blood clotting, cytokine storm cycle development, increased hypoxia also results this.In summary, immune system, coagulation, renin-angiotensin-aldosterone cardiac contractility four primary areas identified.

Language: Английский