Science China Chemistry, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 19, 2024
Language: Английский
Science China Chemistry, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 19, 2024
Language: Английский
Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 538, P. 216710 - 216710
Published: April 18, 2025
Language: Английский
Citations
0International Microbiology, Journal Year: 2025, Volume and Issue: unknown
Published: May 7, 2025
Language: Английский
Citations
0Phytomedicine, Journal Year: 2025, Volume and Issue: unknown, P. 156838 - 156838
Published: May 1, 2025
Language: Английский
Citations
0Water, Journal Year: 2024, Volume and Issue: 16(21), P. 3080 - 3080
Published: Oct. 28, 2024
Water quality degradation and eutrophication of lakes are global ecological environmental concerns, especially shallow lakes. This study collected hydrochemical data from 2935 samples the Chinese part Xingkai (Khanka) Lake, based on 40 published papers spanning period 2001 to 2023. Using water index (WQI), improved geo-accumulation (Igeo), redundancy analysis (RDA), we analyzed overall contamination characteristics environment in Lake. Additionally, explored impact climate change human activities lake’s quality. The results showed that annual WQI for Lake ranged 47.3 72, with a general downward trend, indicating improving Notably, average May total nitrogen (TN) content decreased significantly, signaling further improvement concentration TN sediments was 1401.3 mg/kg, reflecting mild contamination. Igeo values heavy metals Hg Cr were greater than 1, moderate contamination, while Cd Pb between 0 which is range uncontaminated moderately contaminated. Land use (average temperature precipitation) key factors influencing quality, cumulative explanatory ratios 67.3% 50.1%. utilized land-use as metric activities, highlighting potential impacts It offers vital insights sustainable management provides valuable references into similar transboundary
Language: Английский
Citations
3PeerJ, Journal Year: 2024, Volume and Issue: 12, P. e17034 - e17034
Published: Feb. 28, 2024
The use of pesticides to control pests, weeds, and diseases or regulate plant growth is indispensable in agricultural production. However, the excessive these chemicals has led significant concern about their potential negative impacts on health environment. Phosmet one such pesticide that commonly used plants animals against cold moth, aphids, mites, suckers, fruit flies. Here, we investigated effects phosmet a model organism, Daphnia magna using acute chronic toxicity endpoints as lethality, mobility, genotoxicity, reproduction, gene expression. We performed survival experiments six-well plates at seven different concentrations (0.01, 0.1, 1, 10, 25, 50, 100 μM) well three replicates. observed statistically mortality rates 25 µM above upon 24 h exposure, 1 following 48 exposure. Genotoxicity analysis, reproduction assay qPCR analysis were carried out 0.01 0.1 μM did not show any lethality. Comet showed exposure resulted DNA damage cells. Interestingly, produced more offspring per adult compared group indicating hormetic response. Gene expression profiles demonstrated several genes involved physiological pathways, including oxidative stress, detoxification, immune system, hypoxia iron homeostasis. Taken together, our results indicate dose- time-dependent manner could also induce lethal toxicities other aquatic organisms.
Language: Английский
Citations
2The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 927, P. 172041 - 172041
Published: March 28, 2024
Language: Английский
Citations
2Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 424, P. 136878 - 136878
Published: Nov. 5, 2024
Language: Английский
Citations
2Environmental Research, Journal Year: 2024, Volume and Issue: 260, P. 119677 - 119677
Published: July 23, 2024
Language: Английский
Citations
1Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 478, P. 135582 - 135582
Published: Aug. 22, 2024
Language: Английский
Citations
1bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 17, 2024
Abstract This study presents an in silico analysis of the toxicity Organophosphates (OPs) through their interaction with Human Serum Albumin (HSA) protein using density functional theory (DFT) and molecular docking approaches. Organophosphates, known for widespread use as pesticides, have raised significant concerns due to potential toxicological effects. To investigate mechanisms underlying OP toxicity, we conducted DFT calculations determine electronic properties reactivity selective compounds. Molecular simulations were performed explore binding affinity, sites, conformational changes HSA upon exposure OPs. The revealed key descriptors, such HOMO-LUMO gap electrostatic potential, that indicate high OPs biological molecules. Docking results showed strong affinities between HSA, particularly at sites involved metabolite drug transport, suggesting interference protein’s native function. was further supported by dynamics simulations, which confirmed stability OP-HSA complex over time. These findings provide critical insights into basis organophosphate emphasizing importance HSA. combined approach offers a valuable framework predicting behavior lays foundation vitro vivo studies. Graphical
Language: Английский
Citations
1