In Vivo Oxidative Stress Responses and Mechanism to Chlorinated and Methylated P -Benzoquinone Oxidation Byproducts: A Comparison Study DOI
Qiang Cheng,

Weixu Tang,

Zirui Liu

et al.

Published: Jan. 1, 2024

Language: Английский

Gibberellic acid (GA) induces developmental toxicity in zebrafish (Danio rerio) embryos via oxidative stress DOI
Ying Wei, Yan Gao, Sida Zhang

et al.

Aquatic Toxicology, Journal Year: 2025, Volume and Issue: 279, P. 107247 - 107247

Published: Jan. 11, 2025

Language: Английский

Citations

0
Transgenerational toxicity assessment of [C8mim]Br: Focus on early development, antioxidant defense, and transcriptome profiles in zebrafish DOI Creative Commons

Fei Zhao,

Ying Shen, Zhongjun Ma

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 291, P. 117884 - 117884

Published: Feb. 1, 2025

Language: Английский

Citations

0
In vivo oxidative stress responses and mechanism to chlorinated and methylated p-benzoquinone oxidation byproducts: A comparison study DOI Creative Commons
Qiang Cheng,

Weixu Tang,

Zirui Liu

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 291, P. 117914 - 117914

Published: Feb. 1, 2025

Halogen-substituted para-benzoquinones (p-BQs) are emerging disinfection byproducts known to induce oxidative damage both in vitro and vivo. However, as ubiquitous oxidation byproducts, the vivo toxicity transport mechanism of non-halogenated p-BQs with similar structure α, β-unsaturated ketones halogenated have not been thoroughly investigated. In this study, effect substituents on transportation 2-chloro-1,4-benzoquinone (CBQ) 2-methyl-1,4-benzoquinone (MBQ) was systematically The results show that MBQ exhibits slightly lower acute zebrafish embryos compared CBQ. Exposure CBQ at concentration 10 μg/L 100 significantly increased levels reactive oxygen species, enhanced activities total superoxide dismutase, catalase, glutathione peroxidase, while malformations were primarily observed exposure groups. varying developmental associated significant upregulation genes by only 6 MBQ. Using high-resolution mass spectrometry electron paramagnetic resonance spectroscopy, hydroxylation MBQ, production semiquinone radicals hydroxyl aqueous environments revealed. This study has demonstrated should be overlooked contributes understanding generated radicals, leading excessive oxidative-stress

Language: Английский

Citations

0
Impact of Tributyltin (TBT) on Energy Metabolism and Redox Homeostasis in Blue Crab Callinectes sapidus DOI Creative Commons
Leonardo Airton Ressel Simões,

Rafaella Sanfelice Normann,

Daniela Drosdowski

et al.

Metabolites, Journal Year: 2025, Volume and Issue: 15(4), P. 253 - 253

Published: April 8, 2025

Background/Objectives: Tributyltin (TBT), a potent biocide used in antifouling paints, is highly toxic to aquatic environments, causing oxidative stress, endocrine dysfunction, and metabolic disorders organisms, including crustaceans. The blue crab Callinectes sapidus an economically ecologically important species several countries worldwide considered invasive Europe. Methods: This study evaluated the effects of 7 days exposure environmentally relevant TBT concentrations (100 1000 ng.L−1) on intermediary metabolism balance sapidus. After exposure, hemolymph samples were analyzed determine glucose, lactate, total protein, cholesterol levels. In tissue samples, triglycerides, glycogen, glutathione (GSH), reactive oxygen (ROS), sulfhydryls, lipid peroxidation (LPO), S-transferase (GST) activity assessed. Results: hemolymph, glucose lactate levels increased, while cholesterol, proteins decreased all exposed groups. GST increased tissues, GSH sulfhydryl content decreased. ROS concentration response higher concentrations. Conclusions: These findings highlight toxicity show that disrupts homeostasis C. Additionally, this demonstrates sensitive has potential as model for ecotoxicological studies.

Language: Английский

Citations

0
6PPD induces cerebrovascular defects by triggering oxidative stress and ferroptosis in zebrafish DOI

Mengzhu Lv,

Xiaoyu Mao,

Zheng Lu

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 958, P. 178004 - 178004

Published: Dec. 16, 2024

Language: Английский

Citations

2
MXene/Ag-Based Zwitterionic Double-Network Hydrogels with Enhanced Mechanical Strength and Antifouling Performances DOI

Yangkai Xiong,

Zhiqiang Fang, Jipeng Li

et al.

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: 17(2), P. 4231 - 4238

Published: Dec. 31, 2024

Biological fouling seriously jeopardizes the development of marine industry. Although hydrogels, as a kind state-of-the-art antifouling material, have received wide attention, their mechanical strength is still relatively weak, and synergistic method comparatively single, thus limiting performance hydrogels. Here, zwitterionic sulfobetaine methacrylate (SBMA)-acrylamide (AM)/sodium alginate (SA) double-network (DN) hydrogel with superb ability outstanding properties was prepared by grafting MXene/Ag (M/Ag) powerful biocide polyhexamethylene biguanide (PHMB). The M/Ag has great bactericidal effect (99.9%), DN-M/Ag-PHMB demonstrates high tensile (5.8 MPa), remarkable antiprotein adhesion, bactericidal, antialgal adhesion. This work proves that an exceptional in all three stages biofouling formation promising future new type green material.

Language: Английский

Citations

1
In Vivo Oxidative Stress Responses and Mechanism to Chlorinated and Methylated P -Benzoquinone Oxidation Byproducts: A Comparison Study DOI
Qiang Cheng,

Weixu Tang,

Zirui Liu

et al.

Published: Jan. 1, 2024

Language: Английский

Citations

0