Chemical ingredients in personal care products and their hormetic effects on freshwater photobacteria DOI Open Access
Kai Li, Xiangwei Li, Ya-Qian Xu

et al.

Journal of Environmental Exposure Assessment, Journal Year: 2024, Volume and Issue: 3(4)

Published: Dec. 24, 2024

Personal care products (PCPs), including skin lotions, toners, and make-up waters, are ubiquitous in daily life. Prior research has demonstrated hormesis, a biphasic dose-response phenomenon, these PCPs on the freshwater photobacterium Vibrio qinghaiensis sp. -Q67 (Q67). Given that contain various active chemical components, their hormetic effects intricately linked to ingredients. However, studies focusing concentration-response relationships of individual PCP ingredients scarce. Building upon our previous work, we analyzed 6 employed Q67 as model organism investigate Our analysis representative revealed 49 ingredients, categorized into 10 moisturizers, 5 preservatives, emulsifiers, emollients, 20 with known efficacy, 4 unknown efficacy. Among 30 water-soluble ones were suitable for toxicity testing. At 0.25 h, 23 exhibited S-shaped curves (CRCs) EC50 values spanning from 6.943E-5 g/mL [lactic acid (LAA)] 1.032 [sorbitol (SBO)], while 2 [PEG-7 glyceryl cocoate (PGC) Tween 80 (TW80)] showed hormesis J-shaped CRCs, [adenosine (ADE), dexpanthenol (DEX), E4C, E6C, serine (SER)] lacked discernible CRCs. 12 13 displayed CRCs ranging 4.402E-5 (E6C) 1.961E-1 [dicaprylyl carbonate (DIC)], 16 EC50, zero effective concentration point (ZEP), ECmin, Emin indicating consistent variation range orders magnitude. These findings underscore importance considering assessing risks associated PCPs.

Language: Английский

PROPYLPARABEN NEGATIVELY IMPACTS IN VITRO PREIMPLANTATION MOUSE EMBRYO DEVELOPMENT DOI

Nastasia Zhen Ee Lai,

S.T. Bashir, Ayelet Ziv‐Gal

et al.

Reproductive Toxicology, Journal Year: 2025, Volume and Issue: 133, P. 108876 - 108876

Published: March 3, 2025

Language: Английский

Citations

0
Polystyrene microplastics exposure: Disruption of intestinal barrier integrity and hepatic function in infant mice DOI Creative Commons
Huan Li,

Shimin Xu,

Feng Zhou

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 288, P. 117357 - 117357

Published: Nov. 21, 2024

Language: Английский

Citations

2
Chemical ingredients in personal care products and their hormetic effects on freshwater photobacteria DOI Open Access
Kai Li, Xiangwei Li, Ya-Qian Xu

et al.

Journal of Environmental Exposure Assessment, Journal Year: 2024, Volume and Issue: 3(4)

Published: Dec. 24, 2024

Personal care products (PCPs), including skin lotions, toners, and make-up waters, are ubiquitous in daily life. Prior research has demonstrated hormesis, a biphasic dose-response phenomenon, these PCPs on the freshwater photobacterium Vibrio qinghaiensis sp. -Q67 (Q67). Given that contain various active chemical components, their hormetic effects intricately linked to ingredients. However, studies focusing concentration-response relationships of individual PCP ingredients scarce. Building upon our previous work, we analyzed 6 employed Q67 as model organism investigate Our analysis representative revealed 49 ingredients, categorized into 10 moisturizers, 5 preservatives, emulsifiers, emollients, 20 with known efficacy, 4 unknown efficacy. Among 30 water-soluble ones were suitable for toxicity testing. At 0.25 h, 23 exhibited S-shaped curves (CRCs) EC50 values spanning from 6.943E-5 g/mL [lactic acid (LAA)] 1.032 [sorbitol (SBO)], while 2 [PEG-7 glyceryl cocoate (PGC) Tween 80 (TW80)] showed hormesis J-shaped CRCs, [adenosine (ADE), dexpanthenol (DEX), E4C, E6C, serine (SER)] lacked discernible CRCs. 12 13 displayed CRCs ranging 4.402E-5 (E6C) 1.961E-1 [dicaprylyl carbonate (DIC)], 16 EC50, zero effective concentration point (ZEP), ECmin, Emin indicating consistent variation range orders magnitude. These findings underscore importance considering assessing risks associated PCPs.

Language: Английский

Citations

0