On Substantiation of Reference Blood Levels of Polycyclic Aromatic Hydrocarbons in Children and Adolescents Based on Their Hormone Profile Criteria DOI
Tatyana V. Nurislamova, Оleg V. Dolgikh,

Tatyana D. Karnazhitskaya

et al.

ЗДОРОВЬЕ НАСЕЛЕНИЯ И СРЕДА ОБИТАНИЯ - ЗНиСО / PUBLIC HEALTH AND LIFE ENVIRONMENT, Journal Year: 2024, Volume and Issue: unknown, P. 48 - 55

Published: Dec. 1, 2024

Introduction: Polycyclic aromatic hydrocarbons (PAH/polyarenes) as endocrine disruptors affect the excretion of thyroid hormones. To assess disorders following PAH exposures, blood level thyroid-stimulating hormones is tested. Objectives: study relationship between concentrations polycyclic and hormone to substantiate maximum no-effect levels in children adolescents based on their profile test results. Materials methods: In 2022–2023, comprehensive chemical clinical laboratory tests for aged 4 14 years (n = 81) were conducted ambient air samples analyzed areas with without exposures airborne pollutants. The PAHs antibody serum was established using regression analysis. concentration marker exposure determined upper limit 95 % confidence interval exponential model. Results: observation area, significantly higher polyarenes exceeding those measured reference area by 1.7–2.8 times 3.5–9.9 times, respectively (p ≤ 0.05). A (TSH) a lower urinary iodine from group. Based TSH level, no-observed-effect naphthalene, anthracene, pyrene identified. Discussion: biomarkers effect reflect nature impact individual function. Maximum pediatric population help health risks inhalation exposures. Conclusion: expression criterion, 4–14 have been established, recommended safety criteria under chronic hydrocarbons.

Language: Английский

Associations Between Prenatal Dioxin-like Polychlorinated Biphenyls Exposure and Glucocorticoid and Androgenic Hormones in Umbilical Cord Blood DOI

Mingcong She,

Xuefeng Lv,

Shuhui Chu

et al.

Environmental Research, Journal Year: 2025, Volume and Issue: unknown, P. 120927 - 120927

Published: Jan. 1, 2025

Language: Английский

Citations

0
Associations of metals with hemoglobin and anemia in a Chinese early adolescent cohort DOI Creative Commons
Mengyuan Yuan,

Ting Tang,

Yonghan Li

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 295, P. 118122 - 118122

Published: April 1, 2025

Language: Английский

Citations

0
Urinary Iodine Metabolomics as a Novel Tool for Understanding Environmentally Induced Thyroid Hormone Metabolic Alteration DOI

Qianqian Chai,

Yan Lin,

Yifang Zhu

et al.

Environmental Science & Technology Letters, Journal Year: 2024, Volume and Issue: 11(8), P. 805 - 811

Published: July 5, 2024

Language: Английский

Citations

2
Prenatal polycyclic aromatic hydrocarbon exposure and neurodevelopment among children in Puerto Rico DOI

Savannah M. Sturla Irizarry,

Amber L. Cathey, Emily Zimmerman

et al.

Chemosphere, Journal Year: 2024, Volume and Issue: 366, P. 143468 - 143468

Published: Oct. 1, 2024

Language: Английский

Citations

0
Hypocalcemia as biological mechanism responsible for prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) and anemia: Insights from Zunyi birth cohort DOI
Lei Luo, Weiqiang Yang, Haonan Zhang

et al.

Journal of Environmental Sciences, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 1, 2024

Language: Английский

Citations

0
Exposure to oxygenated polycyclic aromatic hydrocarbons and endocrine dysfunction: Multi-level study based on hormone receptor responses DOI
Ying Ren, Yue Wang, Yang Wang

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 485, P. 136855 - 136855

Published: Dec. 12, 2024

Language: Английский

Citations

0
On Substantiation of Reference Blood Levels of Polycyclic Aromatic Hydrocarbons in Children and Adolescents Based on Their Hormone Profile Criteria DOI
Tatyana V. Nurislamova, Оleg V. Dolgikh,

Tatyana D. Karnazhitskaya

et al.

ЗДОРОВЬЕ НАСЕЛЕНИЯ И СРЕДА ОБИТАНИЯ - ЗНиСО / PUBLIC HEALTH AND LIFE ENVIRONMENT, Journal Year: 2024, Volume and Issue: unknown, P. 48 - 55

Published: Dec. 1, 2024

Introduction: Polycyclic aromatic hydrocarbons (PAH/polyarenes) as endocrine disruptors affect the excretion of thyroid hormones. To assess disorders following PAH exposures, blood level thyroid-stimulating hormones is tested. Objectives: study relationship between concentrations polycyclic and hormone to substantiate maximum no-effect levels in children adolescents based on their profile test results. Materials methods: In 2022–2023, comprehensive chemical clinical laboratory tests for aged 4 14 years (n = 81) were conducted ambient air samples analyzed areas with without exposures airborne pollutants. The PAHs antibody serum was established using regression analysis. concentration marker exposure determined upper limit 95 % confidence interval exponential model. Results: observation area, significantly higher polyarenes exceeding those measured reference area by 1.7–2.8 times 3.5–9.9 times, respectively (p ≤ 0.05). A (TSH) a lower urinary iodine from group. Based TSH level, no-observed-effect naphthalene, anthracene, pyrene identified. Discussion: biomarkers effect reflect nature impact individual function. Maximum pediatric population help health risks inhalation exposures. Conclusion: expression criterion, 4–14 have been established, recommended safety criteria under chronic hydrocarbons.

Language: Английский

Citations

0