Dietary Exposure to Pesticide and Veterinary Drug Residues and Their Effects on Human Fertility and Embryo Development: A Global Overview

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(16), P. 9116 - 9116

Published: Aug. 22, 2024

Drug residues that contaminate food and water represent a serious concern for human health. The major concerns regard the possible irrational use of these contaminants, since this might increase amplitude exposure. Multiple sources contribute to overall exposure including agriculture, domestic use, personal, public veterinary healthcare, increasing origin contamination. In review, we focus on crop pesticides drug because their extensive in modern agriculture farming, which ensures production security ever-growing population around world. We discuss with respect worldwide distribution impacts, special attention harmful effects reproduction embryo development, as well link epigenetic alterations, leading intergenerational transgenerational diseases. Among most commonly implicated causing such disorders are organophosphates, glyphosate antibiotics, tetracyclines being frequently reported. This review highlights importance finding new management strategies drugs. Moreover, due still limited knowledge inter- underlie need strengthen research field, so better clarify specific each contaminant long-term impact.

Language: Английский

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Using Mixture and Exposome Methods to Assess the Associations and Interactions of Chemical Biomarkers with Semen Parameters Among Men Attending a Fertility Center

Published: Jan. 1, 2025

Language: Английский

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Associations between urinary antibiotics exposure and semen parameters among adult men: A biomonitoring-based cross-sectional study

Environmental Pollution, Journal Year: 2025, Volume and Issue: 375, P. 126335 - 126335

Published: April 29, 2025

Language: Английский

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Dietary Exposure to Pesticide and Veterinary Drugs Residues and Their Effects on Human Fertility and Embryo Development: A Global Overview

Published: Aug. 13, 2024

Drug residues that contaminate food and water represent a serious concern for human health, since their irrational use is constantly increasing the amplitude of exposure. Multiple sources contribute to overall exposure contaminants, including agriculture, domestic use, personal, public, veterinary healthcare, possible origin contamination. In this review, we focus on crop pesticides drug because extensive in modern agriculture farming, which ensures production security ever-growing population around world. We discuss with respect worldwide distribution impacts, special attention harmful effects reproduction embryo development, as well link epigenetic alterations, leading intergenerational transgenerational diseases. Among most commonly implicated causing such disorders are organophosphates, glyphosate antibiotics, tetracyclines being frequently reported. This review highlights importance finding new management strategies drugs. Moreover, due still limited knowledge inter- these underlie need strengthen research field, so better clarify specific each contaminant long-term impact.

Language: Английский

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Altered Expression of Thyroid- and Calcium Ion Channels-Related Genes in Rat Testes by Short-Term Exposure to Commercial Herbicides Paraquat or 2,4-D

Journal of Xenobiotics, Journal Year: 2024, Volume and Issue: 14(4), P. 1450 - 1464

Published: Oct. 9, 2024

Exposure to pesticides such as paraquat and 2,4-dichlorophenoxyacetic acid (2,4-D) has been linked harmful health effects, including alterations in male reproduction. Both herbicides are widely used developing countries have associated with reproductive alterations, disruption of spermatogenesis steroidogenesis. The thyroid axis Ca

Language: Английский

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