Aminophenol Molecular Capture Layer for Specific Molecular Sensing with Field-Effect Devices DOI

Pooja Verma,

Yuval Ben‐Shahar, Soumadri Samanta

et al.

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: March 11, 2025

There is an urgent need today for interface management with recognition layers composed of short receptor molecules, excellent specificity and affinity toward a target molecule, wide range sensing applications. The current work demonstrates specific detection G-type nerve agent, which based on nucleophilic substitution reaction between the surface-bound 4-amino-2-((dimethylamino)methyl)phenol (amino-2-DMAMP) receptors diethyl chlorophosphate (DCP) simulant. 2-DMAMP DCP are demonstrated 31P-nuclear magnetic resonance (NMR) electrospray ionization mass spectrometry (ESI-MS/MS). proposed layer utilized through design realization electronic chemosensor using meta-nanochannel field-effect transistor (MNC FET). SiO2 area MNC FET functionalized amino-2-DMAMP amine-based chemistry, response quantified. An demonstrated, coupled limit 1 pg/mL, dynamic 8 orders magnitude, linearity sensitivity. high grade pave way to specific, label-free, quantitative, low-cost, easy-to-operate, field-deployable sensors.

Language: Английский

Aminophenol Molecular Capture Layer for Specific Molecular Sensing with Field-Effect Devices DOI

Pooja Verma,

Yuval Ben‐Shahar, Soumadri Samanta

et al.

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: March 11, 2025

There is an urgent need today for interface management with recognition layers composed of short receptor molecules, excellent specificity and affinity toward a target molecule, wide range sensing applications. The current work demonstrates specific detection G-type nerve agent, which based on nucleophilic substitution reaction between the surface-bound 4-amino-2-((dimethylamino)methyl)phenol (amino-2-DMAMP) receptors diethyl chlorophosphate (DCP) simulant. 2-DMAMP DCP are demonstrated 31P-nuclear magnetic resonance (NMR) electrospray ionization mass spectrometry (ESI-MS/MS). proposed layer utilized through design realization electronic chemosensor using meta-nanochannel field-effect transistor (MNC FET). SiO2 area MNC FET functionalized amino-2-DMAMP amine-based chemistry, response quantified. An demonstrated, coupled limit 1 pg/mL, dynamic 8 orders magnitude, linearity sensitivity. high grade pave way to specific, label-free, quantitative, low-cost, easy-to-operate, field-deployable sensors.

Language: Английский

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