Kidney function mediates the effects of four per-and polyfluoroalkyl substances (PFAS) on atherosclerotic cardiovascular disease DOI Creative Commons
Zhengqi Wei,

Keke Wei,

Ming Yang

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 288, P. 117395 - 117395

Published: Nov. 27, 2024

Language: Английский

Celecoxib as a Potential Treatment for Hepatocellular Carcinoma in Populations Exposed to High PFAS Levels DOI

Boshi Sun,

Yuqiao Zhao,

Shifeng Yang

et al.

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 489, P. 137613 - 137613

Published: Feb. 13, 2025

Language: Английский

Citations

0
Evidence of the occurrence, detection, and ecotoxicity studies of perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) in aqueous environments DOI
Elizabeth Oyinkansola Omotola, Chinemerem Ruth Ohoro, James F. Amaku

et al.

Journal of Environmental Health Science and Engineering, Journal Year: 2025, Volume and Issue: 23(1)

Published: Feb. 25, 2025

Language: Английский

Citations

0
PFAS Exposure and Kidney Health with Gut Microbiota, Blood Metabolites, and Multi-Organ Implications Across Medical Specialties DOI
Nicholas A Kerna,

Adina Boulos,

Melany Abreu

et al.

European journal of ecology, biology and agriculture., Journal Year: 2025, Volume and Issue: 2(2), P. 30 - 46

Published: March 1, 2025

PFAS (per- and polyfluoroalkyl substances) exposure has been linked to kidney damage through mechanisms involving gut microbiota dysbiosis alterations in blood metabolites. These disruptions trigger renal inflammation, oxidative stress, metabolic dysregulation, impairing function. significantly alters microbial communities, impacting metabolites like short-chain fatty acids (SCFAs), bile acids, trimethylamine N-oxide (TMAO). imbalances contribute chronic inflammation fibrosis the gut-kidney axis. Additionally, disrupts related energy metabolism, mitochondrial function, lipid oxidation, amino acid metabolism. Biomarkers such as uric acid, creatinine, homocysteine indicate nephrotoxic stress. This paper explores potential by which impact health interactions with It also highlights its effects role affecting multiple body systems that may involve various medical specialists, internists, gastroenterologists, cardiologists, obstetricians, gynecologists, psychiatrists.

Language: Английский

Citations

0
The effect and potential mechanisms of per- and polyfluoroalkyl substances (PFAS) exposure on kidney stone risk DOI Creative Commons
Ying Cui, Albert W. Wu, Hao Liu

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 294, P. 118087 - 118087

Published: March 30, 2025

Language: Английский

Citations

0
Therapeutic intervention with anti-TNF alleviates colonic and hepatic toxicity induced by perfluorooctanoic acid (PFOA) DOI

Wei Li,

Yongjing Qian,

Xiaojing Cai

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 296, P. 118125 - 118125

Published: April 11, 2025

Language: Английский

Citations

0
Kidney function mediates the effects of four per-and polyfluoroalkyl substances (PFAS) on atherosclerotic cardiovascular disease DOI Creative Commons
Zhengqi Wei,

Keke Wei,

Ming Yang

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 288, P. 117395 - 117395

Published: Nov. 27, 2024

Language: Английский

Citations

1