Rising Breast Cancer Rates in Younger Women: Could Dietary Advanced Glycation End Products Be the Missing Link? DOI

Gowtami A. Panguluri,

Victoria J. Findlay

Journal of young women's breast cancer and health., Journal Year: 2024, Volume and Issue: 1(1&2), P. 13 - 19

Published: Jan. 1, 2024

Abstract The incidence of breast cancer is increasing among young women, who are at higher risk aggressive cancer-related deaths. Lifestyle factors, especially diet, known to be changeable factors that can affect development. This review focuses on the published literature connecting dietary advanced glycation end products (AGEs) and cancer, particularly in adolescent adult (AYA) population. To support our analysis, we collected synthesized data from sources such as PubMed, SEER database, American Association Food Nutrition Guidelines, World Health Organization publications within last 15 years. AGEs mainly found ultra-processed foods, well foods high fat sugar, which common Western diet. also created through nonenzymatic glycoxidation during food cooking temperatures. have been linked progression receptor for AGE, activate inflammatory oxidative stress pathways tumor formation. Epidemiological studies preclinical models indicated a intake correlated with an elevated developing poorer survival outcomes women. While connection between evident, there lack research focusing AYA highlights necessity further investigation fully comprehend impact AGE consumption formative years rising We want highlight significance prevention methods. includes initiatives decrease puberty, when simultaneously raising awareness providing education adopting healthy practices engaging regular physical activity. These measures could effective reducing women worldwide.

Language: Английский

Long-term health-related quality of life among adolescent and young adult breast cancer survivors DOI Creative Commons
Noëlle J. M. C. Vrancken Peeters,

Roos Kerklaan,

Carla Vlooswijk

et al.

Quality of Life Research, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 21, 2025

As the prognosis for adolescents and young adults (AYAs) with breast cancer has improved, long-term health-related quality of life (HRQoL) become increasingly important. This study aimed to analyze HRQoL AYA survivors compared an age-matched normative population identify factors associated HRQoL. Secondary analyses were conducted using data from SURVAYA study. The European Organization Research Treatment Cancer Quality Life Questionnaire Core-30 (EORTC QLQ-C30) was used assess Mann-Whitney U test compare scores those (n = 409). Linear regression models constructed patient treatment characteristics A total 944 female included, a median age 36.0 years follow-up 12.2 years. scored significantly lower on five functional scales: physical, role, emotional, cognitive, social, higher symptom fatigue, pain, dyspnea, insomnia, financial impact population. Being in relationship, having positive body image, adaptive coping positively HRQoL, while older age, chemotherapy, unemployment, maladaptive negatively associated. experience compromised These results highlight need tailored care support, as well importance shared decision-making about benefits risks treatments before initiation.

Language: Английский

Citations

0
Let’s talk about sex! Why should healthcare professionals address sexual distress in breast cancer patients and survivors? DOI
Anouk S. Huberts, Noëlle J. M. C. Vrancken Peeters, Hester Pastoor

et al.

European Journal of Oncology Nursing, Journal Year: 2024, Volume and Issue: 71, P. 102606 - 102606

Published: May 11, 2024

Language: Английский

Citations

0
Rising Breast Cancer Rates in Younger Women: Could Dietary Advanced Glycation End Products Be the Missing Link? DOI

Gowtami A. Panguluri,

Victoria J. Findlay

Journal of young women's breast cancer and health., Journal Year: 2024, Volume and Issue: 1(1&2), P. 13 - 19

Published: Jan. 1, 2024

Abstract The incidence of breast cancer is increasing among young women, who are at higher risk aggressive cancer-related deaths. Lifestyle factors, especially diet, known to be changeable factors that can affect development. This review focuses on the published literature connecting dietary advanced glycation end products (AGEs) and cancer, particularly in adolescent adult (AYA) population. To support our analysis, we collected synthesized data from sources such as PubMed, SEER database, American Association Food Nutrition Guidelines, World Health Organization publications within last 15 years. AGEs mainly found ultra-processed foods, well foods high fat sugar, which common Western diet. also created through nonenzymatic glycoxidation during food cooking temperatures. have been linked progression receptor for AGE, activate inflammatory oxidative stress pathways tumor formation. Epidemiological studies preclinical models indicated a intake correlated with an elevated developing poorer survival outcomes women. While connection between evident, there lack research focusing AYA highlights necessity further investigation fully comprehend impact AGE consumption formative years rising We want highlight significance prevention methods. includes initiatives decrease puberty, when simultaneously raising awareness providing education adopting healthy practices engaging regular physical activity. These measures could effective reducing women worldwide.

Language: Английский

Citations

0