Peroxidase-mimicking activities, photothermal, and antibiotic efficiency of silver selenide nanoparticles as an anti-methicillin-resistant Staphylococcus aureus agent DOI

Leila Fatolahi,

Wadhah Hasan Alkhazali,

Anmar Ghanim Taki

et al.

International Journal of Environmental Health Research, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 11

Published: April 24, 2025

A new antibacterial mechanism developed by using multiple pathways is important to resolve the prevalence of antibiotic-resistant bacteria. This study shows photothermal properties Ag2Se nanoparticles under near-infrared (NIR) in a peroxidase-mimicking reaction. The conversion response 47.85% 808 nm NIR irradiation. Moreover, show activity ineffective β-lactam antibiotic ceftazidime (CAZ) against methicillin-resistant Staphylococcus aureus (MRSA) and increased membrane permeability MRSA. Under synergistic conditions, killed 3.8 log10 MRSA presence NIR, CAZ, H2O2, which higher than + H2O2 (3.4 log10) or CAZ (2.9 log10). hyperthermia generated irradiation, ROS from catalyzing synergy with accounted showed highest influence Ag2Se.

Language: Английский

Peroxidase-mimicking activities, photothermal, and antibiotic efficiency of silver selenide nanoparticles as an anti-methicillin-resistant Staphylococcus aureus agent DOI

Leila Fatolahi,

Wadhah Hasan Alkhazali,

Anmar Ghanim Taki

et al.

International Journal of Environmental Health Research, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 11

Published: April 24, 2025

A new antibacterial mechanism developed by using multiple pathways is important to resolve the prevalence of antibiotic-resistant bacteria. This study shows photothermal properties Ag2Se nanoparticles under near-infrared (NIR) in a peroxidase-mimicking reaction. The conversion response 47.85% 808 nm NIR irradiation. Moreover, show activity ineffective β-lactam antibiotic ceftazidime (CAZ) against methicillin-resistant Staphylococcus aureus (MRSA) and increased membrane permeability MRSA. Under synergistic conditions, killed 3.8 log10 MRSA presence NIR, CAZ, H2O2, which higher than + H2O2 (3.4 log10) or CAZ (2.9 log10). hyperthermia generated irradiation, ROS from catalyzing synergy with accounted showed highest influence Ag2Se.

Language: Английский

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