Stenotrophomonas pavanii MY01 induces phosphate precipitation of Cu(II) and Zn(II) by degrading glyphosate: performance, pathway and possible genes involved DOI Creative Commons

Shengchen Zhao,

Zitong Xu,

Jihong Wang

et al.

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: Oct. 23, 2024

Microbial bioremediation is an advanced technique for removing herbicides and heavy metals from agricultural soil. In this study, the strain Stenotrophomonas pavanii MY01 was used its ability to degrade glyphosate, a phosphorus-containing organic compound, producing PO 4 3− as byproduct. known form stable precipitates with metals, indicating that could potentially remove by degrading glyphosate. Therefore, present experiment induced phosphate precipitation Cu(II) (Hereinafter referred Cu 2+ ) Zn(II) Zn glyphosate MY01. Meanwhile, whole genome of mined degradation mechanism metal removal mechanism. The results study showed degraded best at 34°C, pH = 7.7, inoculum 0.7%, reaching 72.98% within 3d. highest in test 75.95 68.54%, respectively. A comparison MY01’s genes protein sequences GE000474 GE002603 had strong similarity oxidoreductase C-P lyase. This suggests these may be key strain’s GE001435 sequence appears related pathway, which enable excretion into environment, where it forms coordination complexes metals.

Language: Английский

Pesticides exposure and compromised fitness in wild birds: Focusing on the reproductive endocrine disruption DOI

Banalata Mohanty

Pesticide Biochemistry and Physiology, Journal Year: 2024, Volume and Issue: 199, P. 105800 - 105800

Published: Jan. 28, 2024

Language: Английский

Citations

9

Detection of glyphosate, glufosinate, and their metabolites in multi-floral honey for food safety DOI
Giulia Rampazzo, Maria Nobile, Stefania Carpino

et al.

Food Additives & Contaminants Part A, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 10

Published: Jan. 10, 2025

Beehives can accumulate environmental contaminants as bees gather pollen, propolis, and water from their surroundings, contaminating hive products like honey. Moreover, in multifloral environments, interact with plants treated different pesticides, often causing higher pesticides concentrations multi-floral honey than mono-floral varieties. Glyphosate glufosinate are both widely used herbicides. accounted for one-third of herbicide sales Europe 2017 continues to raise health concerns, including its potential carcinogenicity. While the European Commission extended glyphosate's authorisation another 10 years 2023, concerns remain about impact on biodiversity human health. This study aimed monitor presence glyphosate, glufosinate, metabolites 100 samples representing Italian production by analysis using IC-HRMS. Results indicated that 12% contained glyphosate residues ranging > LOQ 45 ng g

Language: Английский

Citations

0

Efeitos da exposição ao herbicida à base de glifosato sobre parâmetros renais plasmáticos e morfológicos em camundongos fêmeas com ou sem ovariectomia DOI Creative Commons

Giovana Licoviski,

Daniel da Silva Souza, João Lucas de Paula Xavier

et al.

Cuadernos de Educación y Desarrollo, Journal Year: 2025, Volume and Issue: 17(3), P. e7774 - e7774

Published: March 18, 2025

Estudos demonstraram que os herbicidas à base de glifosato (HBG)s podem estar relacionados a vários prejuízos morfofuncionais aumentam o risco às doenças crônicas. Neste estudo, buscou-se verificar efeitos da exposição um HBG, sobre parâmetros bioquímicos plasmáticos e morfológicos renais, em camundongos fêmeas submetidas ou não ovariectomia. Para se potenciais ao HBG estão associados concentração hormônios ovarianos, grupo C57Bl/6 adultas foram ovariectomizadas (OVX), as demais pseudo-operação (SHAM). Posteriormente SHAM OVX receberam por 60 dias, gavagem diária 0,2 mL água destilada (grupos SHAM0 OVX0) contendo 0,5 mg HBG/kg SHAM0.5 OVX0.5) 50 SHAM50 OVX50). As apresentaram maior peso corporal do SHAM. O dos rins, plasmática creatinina, ureia ácido úrico, morfologia corpúsculo renal similares entre OVX0 SHAM0. A nas concentrações mg/kg modificou corporal, plasmáticas úrico OVX. Contudo, HBG/kg/dia aumentou área espaço Bowman OVX50. Estas alterações indicam impactos na estrutura renal, promovidos pelo herbicida fêmeas, depender circulante ovarianos.

Citations

0

From repellent to risk: DEET’s adverse effects on hormones and bone health in kids DOI Creative Commons
Xinyu Zhu, Wanlu Liu,

Baihao Lin

et al.

Journal of Advanced Research, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Early life bone accumulation, which predicts future fragility fracture risk, is intimately associated with sex hormones. N, N-diethyl-3-methylbenzamide (DEET) the primary and most effective active ingredient widely used globally, especially among children adolescents. However, effects of DEET on hormones mass remain unclear. We aimed to explore adverse exposure elucidate potential mediating roles in This cross-sectional study analyzed 864 adolescents from NHANES 2013-2016. Urinary 3-diethyl-carbamoyl benzoic acid (DCBA) was employed as a biomarker for exposure. The examined relationships between DCBA, hormones, mass, particular focus evaluating independent serial mediation DEET-bone associations. Increased DCBA decreased testosterone (TT), estrogen (E2), free androgen index (FAI), alongside an increase hormone-binding globulin (SHBG) levels, particularly pronounced subjects < 12 years [β% (95 % CI) = -0.081 (-0.144, -0.017), -0.064 (-0.114, -0.013), -0.101 (-0.177, -0.024), 0.020 (-0.009, 0.048), respectively] non-overweight -0.160 (-0.234, -0.086), -0.103 (-0.158, -0.048), -0.195 (-0.282, -0.107), 0.035 (0.012, 0.058), respectively]. Negative dose-response were observed participants -0.011 (-0.018, -0.005) -0.027 (-0.041, -0.013) total mineral density (BMD) content (BMC), respectively], BMC -0.012 (-0.024, 0.000)]. Additionally, TT, E2, SHBG found significantly independently mediate 15.41 79.84 relationship mass. Furthermore, detected SHBG. exerts detrimental effect health by interfering adolescents, warranting heightened public concern.

Language: Английский

Citations

0

The relationship between urinary glyphosate and all-cause and specific-cause mortality: a prospective study DOI Creative Commons
Yi Chen, Zhijian Wu, Meng Li

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: March 28, 2025

Glyphosate (GLY) is a well-known herbicide with significant applications in both agriculture and non-agriculture. However, GLY overuse recent years has resulted detection of residues many crops, endangering human health food safety. Our aim to investigate the relationship between urinary mortality, as well its influencing factors. The National Health Nutrition Examination Survey (NHANES) data from 4740 American adults were examined. Fitted smooth curves, generalized summation models, multiple logistic regression models used mortality. To potential regulatory elements two effects, perform subgroup analysis. During median follow-up 4.03 years, there total 238 all-cause deaths, 75 cardiovascular disease (CVD) deaths 52 cancer deaths. positively correlated Each 1 ng/ml increase was associated 40% increased risk mortality (Hazard ratio (HR) 1.40, 95% confidence interval (CI) 1.09-1.80), an 50% High group compared Low (HR 1.50, CI 1.05-2.14). In analysis, association significantly modified by gender (P for interaction = 0.03), hypertension 0.022). Higher seems be more death, may affect this association. Furthermore, urine have higher effect on people without hypertension.

Language: Английский

Citations

0

Comprehensive Insights Into Genetically Modified Foods: Technological Advances, Nutritional Benefits, Therapeutic Applications, and Health Implications DOI Creative Commons
Mohamad Warda, Samet Tekin,

Nagwa Khafaga

et al.

Food Safety and Health, Journal Year: 2025, Volume and Issue: unknown

Published: April 7, 2025

ABSTRACT You are what you eat. Genetically modified (GM) foods transforming modern agriculture by enhancing nutrition, sustainability, and resilience to environmental challenges. This review highlights the benefits of GM crops, including pest resistance, nutrient enrichment, roles in mycotoxin reduction, biofuel production, pharmaceuticals. Although offer solutions for global food security, concerns persist regarding allergenicity, cancer risk, reproductive health, gut microbiota disruption. Advanced detection methods, such as PCR‐based assays, immunoassays, next‐generation sequencing (NGS), pivotal accurate identification regulation, ensuring unauthorized modifications excluded from supply. Emerging technologies, CRISPR‐based diagnostics, promise greater specificity affordability molecular‐level detection. The advocates a multidisciplinary approach—integrating genetics, immunology, toxicology—to address safety refine technologies. International regulatory frameworks must balance innovation with health safeguards. Consumer education is vital fostering trust acceptance foods. Future developments may include crops fortified against malnutrition, resilient climate change, engineered medicinal properties. Collaboration among researchers, regulators, public critical maximize while their sustainability addressing

Language: Английский

Citations

0

Associations of glyphosate exposure and serum sex steroid hormones among 6–19-year-old children and adolescents DOI Creative Commons
Xiaojie Sun, Huan Zhang, Xiaojing Huang

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 275, P. 116266 - 116266

Published: April 1, 2024

Glyphosate, ranked as one of the most widely used herbicides in world, has raised concerns about its potential disruptive effects on sex hormones. However, limited human evidence was available, especially for children and adolescents. The present study aimed to examine associations between exposure glyphosate hormones among participants aged 6-19 years, utilizing data from National Health Nutrition Examination Survey (NHANES) conducted 2013 2016. Children adolescents who had available urinary glyphosate, serum steroid hormones, including testosterone (TT), estradiol (E

Language: Английский

Citations

2

Effects of glyphosate on sperm quality of the estuarine crab Neohelice granulata, under the “One Health” perspective DOI

Ivana S. Canosa,

Marina Zanitti,

Daniel A. Medesani

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 948, P. 174879 - 174879

Published: July 22, 2024

Language: Английский

Citations

0

Altered ovarian reserve in Ewe lambs exposed to a glyphosate-based herbicide DOI
Ramiro Alarcón,

Ana Laura Alegre,

Oscar E. Rivera

et al.

Chemosphere, Journal Year: 2024, Volume and Issue: 363, P. 142895 - 142895

Published: July 26, 2024

Language: Английский

Citations

0

Chronic dietary exposure to glyphosate-induced connexin 43 autophagic degradation contributes to blood-testis barrier disruption in roosters DOI
Qing Liang, Baoyou Liu,

Tian-Lin Zhang

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 951, P. 175606 - 175606

Published: Aug. 17, 2024

Language: Английский

Citations

0