Advanced Healthcare Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 10, 2025
Abstract
Effective
treatment
of
bone
diseases
is
quite
tricky
due
to
the
unique
nature
tissue
and
complexity
repair
process.
In
combination
with
biological
materials,
cells
factors
can
provide
a
highly
effective
safe
strategy
for
regeneration,
especially
based
on
these
multifunctional
hydrogel
interface
materials.
However,
itis
still
challenge
formulate
materials
fascinating
properties
(e.g.,
activity,
controllable
biodegradability,
mechanical
strength,
excellent
cell/tissue
adhesion,
release
properties)
their
clinical
applications
in
complex
processes.
this
review,
we
will
highlight
recent
advances
developing
functional
hydrogels.
We
then
discuss
barriers
producing
without
sacrificing
inherent
properties,
potential
cartilage
are
discussed.
Multifunctional
serve
as
fundamental
building
block
engineering.
Advanced Functional Materials,
Journal Year:
2024,
Volume and Issue:
34(19)
Published: Jan. 9, 2024
Abstract
Although
recent
years
have
seen
considerable
interest
in
stimuli‐responsive
hydrogels,
their
strict
preparation
conditions
and
narrow
applicability
limit
use
as
diverse
sensors
soft
robots.
Herein,
a
versatile
Agar‐Zwirrions
hybrid
hydrogel
actuator
(Agar/PSBMA)
integrated
with
simultaneous
temperature
self‐sensing
wide‐range
electrical
response
is
developed.
To
prepare
the
Agar/PSBMA
hydrogel,
simple
controllable
preforming
post‐enhancing
mechanical
pressing
method
used
by
introducing
zwitterions
materials
into
temperature‐sensitive
Agar
matrix.
Owing
to
design,
compact
multiplex
complementary
structure
generated
this
can
facilitate
improvement
of
flexibility,
stretchability,
toughness
while
providing
dissipation
adhesion
properties.
Importantly,
visible
detected
ability
during
10–40
°C,
quick
bending
responses
both
high‐voltage
low‐voltage
electric
fields
make
it
unique
over
other
actuators.
Furthermore,
behavior
found
be
impacted
characteristics
charge
polarization
based
on
finite
element
Abaqus
simulations
analysis.
The
prepared
hydrogels
show
potential
for
applications
robotics
controlled
transportation
adhered
substances
simultaneously
monitoring
working
temperature,
which
expands
range
actuators
broadens
scope
application.
Chemical Society Reviews,
Journal Year:
2024,
Volume and Issue:
53(7), P. 3273 - 3301
Published: Jan. 1, 2024
Oral
diseases
are
prevalent
but
challenging
owing
to
the
highly
movable
and
wet,
microbial
inflammatory
environment.
Polymeric
materials
regarded
as
one
of
most
promising
biomaterials
due
their
good
compatibility,
facile
preparation,
flexible
design
obtain
multifunctionality.
Therefore,
a
variety
strategies
have
been
employed
develop
with
improved
therapeutic
efficacy
by
overcoming
physicobiological
barriers
in
oral
diseases.
In
this
review,
we
summarize
polymeric
for
treatment
First,
present
unique
environment
including
environment,
which
hinders
effective
Second,
series
designing
towards
such
highlighted.
For
example,
multifunctional
armed
wet-adhesive,
antimicrobial,
anti-inflammatory
functions
through
advanced
chemistry
nanotechnology
effectively
treat
These
achieved
wet-adhesive
polymers
modified
hydroxy,
amine,
quinone,
aldehyde
groups
provide
strong
wet-adhesion
hydrogen
covalent
bonding,
electrostatic
hydrophobic
interactions,
developing
antimicrobial
cationic
polymers,
peptides,
antibiotic-conjugated
synthesizing
phenolic
hydroxy
cysteine
that
function
immunomodulators
electron
donors
reactive
oxygen
species
reduce
inflammation.
Third,
various
delivery
systems
enhanced
mucosa
biofilm
penetration
capabilities,
nanoparticles,
hydrogels,
patches,
microneedles,
constructed
antibiotics,
immunomodulators,
antioxidants
achieve
efficacy.
Finally,
insights
into
challenges
future
development
promise
clinical
translation.
International Journal of Molecular Sciences,
Journal Year:
2023,
Volume and Issue:
24(4), P. 3963 - 3963
Published: Feb. 16, 2023
The
development
of
a
novel
artificial
heart
valve
with
outstanding
durability
and
safety
has
remained
challenge
since
the
first
mechanical
entered
market
65
years
ago.
Recent
progress
in
high-molecular
compounds
opened
new
horizons
overcoming
major
drawbacks
tissue
valves
(dysfunction
failure,
degradation,
calcification,
high
immunogenic
potential,
risk
thrombosis),
providing
insights
into
an
ideal
valve.
Polymeric
can
best
mimic
tissue-level
behavior
native
valves.
This
review
summarizes
evolution
polymeric
state-of-the-art
approaches
to
their
development,
fabrication,
manufacturing.
discusses
biocompatibility
testing
previously
investigated
materials
presents
most
recent
developments,
including
human
clinical
trials
LifePolymer.
New
promising
functional
polymers,
nanocomposite
biomaterials,
designs
are
discussed
terms
potential
application
superiority
inferiority
hybrid
non-modified
polymers
reported.
proposes
several
concepts
potentially
suitable
address
above-mentioned
challenges
arising
R&D
from
properties,
structure,
surface
materials.
Additive
manufacturing,
nanotechnology,
anisotropy
control,
machine
learning,
advanced
modeling
tools
have
given
green
light
set
directions
for
Polymers,
Journal Year:
2024,
Volume and Issue:
16(14), P. 1991 - 1991
Published: July 11, 2024
Natural
hydrogels
based
on
renewable
and
inexpensive
sources,
such
as
starch,
represent
an
interesting
group
of
biopolymeric
materials
with
a
growing
range
applications
in
the
biomedical,
cosmeceutical,
food
sectors.
Starch-based
have
traditionally
been
produced
using
different
processes
chemical
or
physical
methods.
However,
long
processing
times,
high
energy
consumption,
safety
issues
related
to
synthesis
these
materials,
mostly
causing
severe
environmental
damage,
identified
main
limitations
for
their
further
exploitation.
Therefore,
scientific
challenge
research
groups
is
development
reliable
sustainable
methods
reduce
footprint,
well
investigating
new
low-cost
sources
starches
individuating
appropriate
formulations
produce
stable
hydrogel-based
products.
In
last
decade,
possibility
physically
modifying
natural
polysaccharides,
starches,
green
has
nonthermal
technologies
including
high-pressure
(HPP).
It
demonstrated
that
latter
exerts
important
role
improving
physicochemical
techno-functional
properties
starches.
surveys
literature,
activities
devoted
understanding
effects
pre-treatments
via
(HPP)
starch
structural
modifications,
more
so
than
elucidating
its
capacity
rapid
formation
highly
structured
starch-based
promising
functionality
stability,
utilizing
eco-friendly
conditions.
present
review
addresses
recent
advancements
knowledge
production
HPP
innovative
clean-label
preparation
method.
Additionally,
this
manuscript
ambition
give
updated
overview
considering
types
structures
available,
are
proposed
critically
analyze
perspectives
technological
challenges
future
exploitation
novel
structures.
