Journal of Nanobiotechnology,
Journal Year:
2025,
Volume and Issue:
23(1)
Published: March 5, 2025
Photoacoustic
brain
imaging
(PABI)
has
emerged
as
a
promising
biomedical
modality,
combining
high
contrast
of
optical
with
deep
tissue
penetration
ultrasound
imaging.
This
review
explores
the
application
photoacoustic
in
tumor
imaging,
highlighting
synergy
between
nanomaterials
and
state
art
techniques
to
achieve
high-resolution
deeper
tissues.
PABI
leverages
effect,
where
absorbed
light
energy
causes
thermoelastic
expansion,
generating
waves
that
are
detected
converted
into
images.
technique
enables
precise
diagnosis,
therapy
monitoring,
enhanced
clinical
screening,
specifically
management
complex
diseases
such
breast
cancer,
lymphatic
disorder,
neurological
conditions.
Despite
integration
agents
radiation,
providing
comprehensive
overview
current
methodologies,
major
obstacles
treatment,
future
directions
for
improving
diagnostic
therapeutic
outcomes.
The
underscores
significance
robust
research
tool
medical
method,
potential
revolutionize
disease
diagnosis
treatment.
CNS & Neurological Disorders - Drug Targets,
Journal Year:
2024,
Volume and Issue:
23(10), P. 1251 - 1262
Published: Feb. 14, 2024
Abstract:
The
potential
of
nanotechnology
in
advancing
the
diagnosis
and
treatment
neurodegenerative
diseases
is
explored
this
comprehensive
literature
review.
findings
these
studies
suggest
that
has
capacity
to
improve
existing
therapeutic
approaches,
create
novel
safe
compounds,
develop
more
precise
imaging
techniques
diagnostic
methods
for
diseases.
With
emergence
nanomedicine
era,
a
new
innovative
approach
diagnosing
treating
conditions
been
introduced.
Notably,
researchers'
development
nanocarrier
drug
delivery
tool
demonstrates
immense
compared
conventional
therapy,
as
it
maximizes
efficacy
minimizes
undesirable
side
effects.
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(15), P. e35655 - e35655
Published: Aug. 1, 2024
Melanoma,
a
lethal
form
of
skin
cancer,
poses
significant
challenge
in
oncology
due
to
its
aggressive
nature
and
high
mortality
rates.
Gold
nanostructures,
including
gold
nanoparticles
(GNPs),
offer
myriad
opportunities
melanoma
therapy
imaging
their
facile
synthesis
functionalization,
robust
stability,
tunable
physicochemical
optical
properties,
biocompatibility.
This
review
explores
the
emerging
role
nanostructures
composites
revolutionizing
treatment
paradigms,
bridging
gap
between
nanotechnology
clinical
oncology,
offering
insights
for
researchers,
clinicians,
stakeholders.
It
begins
by
elucidating
potential
nanotechnology-driven
approaches
cancer
therapy,
highlighting
unique
properties
versatility
GNPs
biomedical
applications.
Various
therapeutic
modalities,
photothermal
photodynamic
targeted
drug
delivery,
gene
nanovaccines,
are
discussed
detail,
along
with
from
ongoing
trials.
In
addition,
utility
theranostics
is
explored,
showcasing
diagnosis,
monitoring,
personalized
medicine.
Furthermore,
safety
considerations
toxicities
associated
addressed,
underscoring
importance
comprehensive
risk
assessment
translation.
Finally,
concludes
discussing
current
challenges
future
directions,
emphasizing
need
innovative
strategies
maximize
impact
therapy.
Journal of Nanobiotechnology,
Journal Year:
2025,
Volume and Issue:
23(1)
Published: March 5, 2025
Photoacoustic
brain
imaging
(PABI)
has
emerged
as
a
promising
biomedical
modality,
combining
high
contrast
of
optical
with
deep
tissue
penetration
ultrasound
imaging.
This
review
explores
the
application
photoacoustic
in
tumor
imaging,
highlighting
synergy
between
nanomaterials
and
state
art
techniques
to
achieve
high-resolution
deeper
tissues.
PABI
leverages
effect,
where
absorbed
light
energy
causes
thermoelastic
expansion,
generating
waves
that
are
detected
converted
into
images.
technique
enables
precise
diagnosis,
therapy
monitoring,
enhanced
clinical
screening,
specifically
management
complex
diseases
such
breast
cancer,
lymphatic
disorder,
neurological
conditions.
Despite
integration
agents
radiation,
providing
comprehensive
overview
current
methodologies,
major
obstacles
treatment,
future
directions
for
improving
diagnostic
therapeutic
outcomes.
The
underscores
significance
robust
research
tool
medical
method,
potential
revolutionize
disease
diagnosis
treatment.
