Current Problems in Cardiology, Journal Year: 2024, Volume and Issue: 49(9), P. 102686 - 102686
Published: June 1, 2024
Language: Английский
European Polymer Journal, Journal Year: 2024, Volume and Issue: 205, P. 112718 - 112718
Published: Jan. 2, 2024
In the contemporary era, novel manufacturing technologies like additive (AM) have revolutionized different engineering sectors including biomedical, aerospace, electronics, etc. Four-dimensional (4D) printing aka AM of smart materials is gaining popularity among scientific community, which has excellent ability to make soft structures such as robots, actuators, and grippers. These are developed by applying various stimuli pH, temperature, magnetic field, many combinations onto materials. Stimuli in 3D permit shape-morphing behaviors bending, twisting, folding, swelling, rolling, shrinking, origami, or locomotion. A wide variety can be fabricated through incorporation hard particles into resulting magneto-active (MASMs). With this integration, magneto-thermal coupling actuation allows diverse magneto-deformations, facilitating development personalized devices that capable enhanced deformation. review, guidelines provided on for MASMs polymers (MAPs), composites, hydrogels (MAHs) booming flexible wearable biomimetic devices. Moreover, 3D-printed robotics an outstanding capacity adapt complicated situations advanced actuating applications. Finally, some current challenges emerging areas exciting technology been proposed. Lastly, it anticipated technological advancements developing intelligent will a significant impact design real-world
Language: Английский
Citations
88
Current Problems in Cardiology, Journal Year: 2023, Volume and Issue: 48(11), P. 101922 - 101922
Published: July 10, 2023
Language: Английский
Citations
87
ACS Omega, Journal Year: 2025, Volume and Issue: 10(1), P. 1207 - 1225
Published: Jan. 3, 2025
Manufacturing bioactive materials for drug delivery involves developing that interact with biological tissues to release drugs in a controlled and targeted manner. The goal is optimize therapeutic efficacy reduce side effects by combining knowledge from engineering, biology, pharmacology. This study presents detailed bibliometric analysis, exploring the keywords "manufacturing," "bioactive materials," "drug delivery" identify highlight significant advancements field. From Web of Science, 36,504 articles were analyzed, 171 selected deeper identifying key journals, countries, institutions, authors. results field's interdisciplinary nature, grouped into four main themes, including regenerative medicine, scaffolds, three-dimensional (3D) printing, glass, tissue engineering. Future research this area will focus on more effective precise systems using technologies like 3D printing nanotechnology enhance customization control release, aiming efficient therapies.
Language: Английский
Citations
6
Current Problems in Cardiology, Journal Year: 2023, Volume and Issue: 49(1), P. 102039 - 102039
Published: Aug. 19, 2023
Language: Английский
Citations
31
Current Problems in Cardiology, Journal Year: 2024, Volume and Issue: 49(6), P. 102568 - 102568
Published: April 8, 2024
Language: Английский
Citations
13
Gels, Journal Year: 2025, Volume and Issue: 11(1), P. 32 - 32
Published: Jan. 2, 2025
New production technologies have transformed modern engineering fields, including electronics, mechanics, robotics, and biomedicine. These advancements led to the creation of smart materials such as alloys, polymers, gels that respond various stimuli. This review focuses on (SMs), their variety fabrication techniques, can be used construct three- or four-dimensional structures. The mechanisms designs materials, limitations current printing technologies, perspectives for future uses are also discussed in this review. printed expected a major impact design real-world applications.
Language: Английский
Citations
2
Biomimetics, Journal Year: 2023, Volume and Issue: 8(4), P. 330 - 330
Published: July 27, 2023
Selective laser sintering (SLS) is an additive manufacturing process that has shown promise in the production of medical devices, including hip cups, knee trays, dental crowns, and hearing aids. SLS-based 3D-printed dosage forms have potential to revolutionise personalised drugs. The ability manipulate porosity printed materials a particularly exciting aspect SLS. Porous tablet formulations produced by SLS can disintegrate orally within seconds, which challenging achieve with traditional methods. also enables creation amorphous solid dispersions single step, rather than multi-step required conventional This review provides overview 3D printing, describes operating mechanism necessary for SLS, highlights recent advances biomedical pharmaceutical applications. Furthermore, in-depth comparison contrast various printing technologies their effectiveness tissue engineering applications presented this review.
Language: Английский
Citations
13
Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(9), P. 2362 - 2362
Published: Sept. 21, 2023
Dual-nozzle fused deposition modeling (FDM) is a 3D printing technique that allows for the simultaneous of two polymeric filaments and design complex geometries. Hence, hybrid formulations structurally different sections can be combined into same dosage form to achieve customized drug release kinetics. The objective this study was develop novel bicompartmental device by dual-nozzle FDM colon-specific delivery. Hydroxypropylmethylcellulose acetate succinate (HPMCAS) polyvinyl alcohol (PVA) were selected as matrix-forming polymers outer pH-dependent inner water-soluble compartments, respectively. 5-Aminosalicylic acid (5-ASA) model drug. Drug-free HPMCAS drug-loaded PVA suitable extruded, their properties assessed thermal, X-ray diffraction, microscopy, texture analysis techniques. 5-ASA (20% w/w) remained mostly crystalline in matrix. Filaments successfully printed devices combining an cylindrical compartment spiral-shaped communicates with external media through opening. Scanning electron microscopy tomography performed guarantee quality 3D-printed devices. In vitro tests demonstrated pH-responsive biphasic pattern: slow sustained period (pH values 1.2 6.8) controlled diffusion followed faster phase 7.4) governed polymer relaxation/erosion. Overall, research demonstrates feasibility obtain innovative targeting colon.
Language: Английский
Citations
11
Future Science OA, Journal Year: 2024, Volume and Issue: 10(1)
Published: March 12, 2024
Language: Английский
Citations
4
Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(6), P. 783 - 783
Published: June 8, 2024
The aim of this study was to fabricate mini-tablets polyhedrons containing theophylline using a fused deposition modeling (FDM) 3D printer, and evaluate the correlation between release kinetics models their geometric shapes. filaments theophylline, hydroxypropyl cellulose (HPC), EUDRAGIT RS PO (EU) could be obtained with consistent thickness through pre-drying before hot melt extrusion (HME). Mini-tablets ranging from tetrahedron icosahedron were 3D-printed same formulation filament, ensuring equal volumes. derived dissolution tests polyhedrons, along calculations for various physical parameters (edge, SA: surface area, SA/W: area/weight, SA/V: area/volume), revealed that Higuchi model SA/V highest (R2 = 0.995). It confirmed 3D- printing development personalized or pediatric drug products allows adjustment dosage by modifying size shape while maintaining controlling profile.
Language: Английский
Citations
4