Synthesis of cellulose nanocrystals from jute fibers for reinforcement in bio-nanocomposite films: fabrication and characterization DOI
Mir Sahidul Ali, Mir Sahanur Ali, Shubhranshu Bhandari

et al.

Deleted Journal, Journal Year: 2024, Volume and Issue: 246(1)

Published: Dec. 11, 2024

Cellulose nanocrystals (CNCs) were synthesized from jute fiber by acid hydrolysis method. Our research aims to fabricate cellulose reinforced methyl (MC) and chitosan (CH) bio-nanocomposites (BNCs) loaded with ketorolac tromethamine (KT) drug. The BNC films fabricated solvent evaporation technique. We have investigated the chemical structure, morphology mechanical properties of formulations using Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), Universal testing machine (UTM), dynamic light scattering (DLS), contact angle (CA) scanning electron microscopy (SEM). CNCs BNCs showed excellent material property which may a broad vista in realistic biomedical application.

Language: Английский

Nanomaterial-Enhanced Microneedles: Emerging Therapies for Diabetes and Obesity DOI Creative Commons
Mehrnaz Abbasi,

Divine Afunu Boka,

Hannah DeLoit

et al.

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(10), P. 1344 - 1344

Published: Oct. 21, 2024

Drug delivery systems (DDS) have improved therapeutic agent administration by enhancing efficacy and patient compliance while minimizing side effects. They enable targeted delivery, controlled release, bioavailability. Transdermal drug (TDDS) offer non-invasive medication evolved to include methods such as chemical enhancers, iontophoresis, microneedles (MN), nanocarriers. MN technology provides innovative solutions for chronic metabolic diseases like diabetes obesity using various types. For management, MNs continuous glucose monitoring, diabetic wound healing, painless insulin delivery. treatment, provide sustained transdermal of anti-obesity drugs or nanoparticles (NPs). Hybrid integrating wearable sensors smart materials enhance treatment effectiveness management. Nanotechnology has advanced nano-scaled liposomes polymeric NPs with MNs. In glucose-responsive facilitate At the same time, lipid nanocarriers in dissolving extended release stability absorption disorder therapies. DDS are advancing toward personalized treatments enhanced nanomaterials. These approaches can outcomes through precise real-time monitoring. However, widespread implementation faces challenges ensuring biocompatibility, improving technologies, scaling production, obtaining regulatory approval. This review will present recent advances developing applying nanomaterial-enhanced management also discussing challenges, limitations, future perspectives these DDS.

Language: Английский

Citations

3

Revolutionizing nanomedicine: Expanding horizons of nanoemulsions in drug delivery and beyond DOI
Mohit Kumar,

Nitasha Chauhan,

Devesh Kumar

et al.

Journal of Dispersion Science and Technology, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 26

Published: June 20, 2024

Nanoemulsions are nano-sized particles, typically ranging from tens to hundreds of nanometers. These nanoemulsions possess various appealing properties, making them highly promising for applications in pharmaceutics, foods, and cosmetics. properties include their small size, which allows a high surface area per unit volume, ability disperse hydrophobic components enhance absorption effectively. In the pharmaceutical industry, have been developed delivery active ingredients. Macromolecular surfactants offer enhanced emulsion stability compared conventional low-molecular surfactants. Enhanced is due slower desorption kinetics at droplet interface, reduces risk toxicity skin irritation associated with latter. This article presents comprehensive investigation into role drug delivery. It commences by delineating types subsequently explores techniques nanoemulsion preparation. Surfactants serve as pivotal both production stabilization nanoemulsions. The review provides an encompassing overview diverse surfactant types, molecule variants, particle surfactants, phospholipids, peptides, protein-based tailored Additionally, it addresses instability, elucidating strategies mitigate instability challenges, highlights utilization nanomedicine effective aims insights researchers engaged nanoemulsion-related studies interdisciplinary fields.

Language: Английский

Citations

1

Nature-inspired solutions: A comprehensive review of biomimetic nanoparticles in nanomedicine DOI
Eliasu Issaka,

Blessing Tornyeava,

Enock Adjei Agyekum

et al.

Journal of Thermoplastic Composite Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 9, 2024

Biomimetic nanoparticles (BioM NPs) are an innovative strategy for nanomedicine (NanoMed) that combines the advantages of artificial materials with biological functioning natural systems. Ongoing research attempts to enhance their design, and stability, solve problems broader applications in medicine biotechnology. NanoMed ideas intensively researched preclinical because they provide unique disease management. It has developed novel therapeutic strategies combating viral infections increasing treatment success rates. The creation nanocarriers drug delivery systems is critical evolution NanoMed, but there still much learn about this quickly evolving field. To contribute existing knowledge cover gaps, our present review article will discuss state-of-the-art BioM NPs three sections. First, methods NP production synergistic interactions human cells, tissues, organs, organ be discussed. Followed by a discussion several NanoMeds (wound healing, targeted delivery, theranostics, cancer therapy, bone formation and/or regeneration), concluding application NPs, challenges associated these applications, prospects.

Language: Английский

Citations

1

Electrospinning of Biocompatible Nanofibres for Medical Coatings: Techniques and Applications DOI
Bancha Yingngam,

Kamonrat Suksumrit,

N. Proykratok

et al.

Royal Society of Chemistry eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 214 - 250

Published: Nov. 15, 2024

The development of biocompatible nanofibres through electrospinning is a promising method for engineers in the biomedical field. existing coating technologies medical field have various limitations, and more investigations are needed to improve their biocompatibility, controlled release properties, mechanical strength. Designing new materials that can interact efficiently with biological systems offer numerous functional advantages major challenge device manufacturing tissue engineering. This chapter reviews approaches used create nanofibres, including design, fabrication functionalization. applications these coatings also reviewed. Furthermore, we discuss methods, used, key parameters impact fibre morphology physiochemical properties. Moreover, incorporation bioactive elements drugs into therapeutic explored. biologically friendly be an effective approach improving coatings. Such enhance properties such as drug delivery, regeneration, implant integration, offering enormous potential patient welfare. Future research areas include investigating use advanced procedures enhanced control over nanofibre composition design fabrication.

Language: Английский

Citations

1

Ionic Liquid-Based Grapeseed Oil Emulsion for Enhanced Anti-Wrinkle Treatment DOI Creative Commons
Bo Yang, Xu Zhang, Liguo Zhang

et al.

Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(10), P. 1273 - 1273

Published: Sept. 26, 2024

To address the poor efficacy and percutaneous penetration of grape seed oil, ionic liquids nanotechnology were combined to prepare a oil emulsion.

Language: Английский

Citations

0

Nanoparticle-Based Drug Delivery for Vascular Applications DOI Creative Commons
Atanu Naskar, Sreenivasulu Kilari, Gaurav Baranwal

et al.

Bioengineering, Journal Year: 2024, Volume and Issue: 11(12), P. 1222 - 1222

Published: Dec. 3, 2024

Nanoparticle (NP)-based drug delivery systems have received widespread attention due to the excellent physicochemical properties of nanomaterials. Different types NPs such as lipid NPs, poly(lactic-co-glycolic) acid (PLGA) inorganic (e.g., iron oxide and Au), carbon (graphene nanodots), 2D nanomaterials, biomimetic found favor vehicles. In this review, we discuss different customized for intravascular delivery, nanoparticle behaviors (margination, adhesion, endothelium uptake) in blood vessels, nanomaterial compatibility successful delivery. Additionally, cell surface protein targets play an important role targeted various vascular studies using nanoparticles conjugated these proteins are reviewed. Finally, limitations, challenges, potential solutions translational research regarding NP-based discussed.

Language: Английский

Citations

0

Synthesis of cellulose nanocrystals from jute fibers for reinforcement in bio-nanocomposite films: fabrication and characterization DOI
Mir Sahidul Ali, Mir Sahanur Ali, Shubhranshu Bhandari

et al.

Deleted Journal, Journal Year: 2024, Volume and Issue: 246(1)

Published: Dec. 11, 2024

Cellulose nanocrystals (CNCs) were synthesized from jute fiber by acid hydrolysis method. Our research aims to fabricate cellulose reinforced methyl (MC) and chitosan (CH) bio-nanocomposites (BNCs) loaded with ketorolac tromethamine (KT) drug. The BNC films fabricated solvent evaporation technique. We have investigated the chemical structure, morphology mechanical properties of formulations using Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), Universal testing machine (UTM), dynamic light scattering (DLS), contact angle (CA) scanning electron microscopy (SEM). CNCs BNCs showed excellent material property which may a broad vista in realistic biomedical application.

Language: Английский

Citations

0