Enhanced delivery of doxorubicin for breast cancer treatment using pH-sensitive starch/PVA/g-C3N4 hydrogel

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 265, P. 130901 - 130901

Published: March 13, 2024

Language: Английский

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Advances in Precision Medicine Approaches for Colorectal Cancer: From Molecular Profiling to Targeted Therapies

ACS Pharmacology & Translational Science, Journal Year: 2024, Volume and Issue: 7(4), P. 967 - 990

Published: March 19, 2024

Precision medicine is transforming colorectal cancer treatment through the integration of advanced technologies and biomarkers, enhancing personalized effective disease management. Identification key driver mutations molecular profiling have deepened our comprehension genetic alterations in cancer, facilitating targeted therapy immunotherapy selection. Biomarkers such as microsatellite instability (MSI) DNA mismatch repair deficiency (dMMR) guide decisions, opening avenues for immunotherapy. Emerging liquid biopsies, artificial intelligence, machine learning promise to revolutionize early detection, monitoring, selection precision medicine. Despite these advancements, ethical regulatory challenges, including equitable access data privacy, emphasize importance responsible implementation. The dynamic nature with its tumor heterogeneity clonal evolution, underscores necessity adaptive strategies. future lies potential enhance patient care, clinical outcomes, understanding this intricate disease, marked by ongoing evolution field. current reviews focus on providing in-depth knowledge various diverse approaches utilized against at both biochemical levels.

Language: Английский

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A comprehensive perspective of trastuzumab-based delivery systems for breast cancer treatment

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 95, P. 105592 - 105592

Published: March 16, 2024

Language: Английский

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A Case Study on Complete Pathological Response in Advanced Rectal Cancer Patient with Oxaliplatin-based Chemotherapy without Cumulative Neurotoxicity

Journal of Gastrointestinal Cancer, Journal Year: 2025, Volume and Issue: 56(1)

Published: April 16, 2025

Language: Английский

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Ephedra herb as a sustainable source: Insights into its role in metal nanoparticle synthesis—A review

Environmental Progress & Sustainable Energy, Journal Year: 2025, Volume and Issue: unknown

Published: April 25, 2025

Abstract There are various physical and chemical techniques for the synthesis of nanoparticles. However, green nanoparticles, particularly biosynthesis metal nanoparticles using plants, has garnered significant interest from researchers worldwide. In addition to being an environmentally safe technique, offers numerous biological applications, including antifungal, antiviral, antibacterial, wound healing, antioxidant, antitumor properties. Ephedra (ma‐huang) is a valuable resource phytochemical components that have pharmaceutical effects, such as phenolic compounds, reducing sugars, flavonoids, alkaloids, tannins, saponins. These which possess antimicrobial antioxidant attracted attention stabilizing agents facilitate metallic oxide Various silver, gold, copper, selenium, arsenic, zinc, been synthesized extracts, demonstrating This study aims investigate utilizing different species plant explore their applications.

Language: Английский

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Fe3+-DOX-Mediated Self-Assembled Nanolipids for Tumor Microenvironment Activated Synergistic Ferroptotic-Chemo Therapy Assisted with MR-imaging

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 415, P. 136039 - 136039

Published: May 26, 2024

Language: Английский

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Biocompatability chitosan /Aloe barbadensis miller loaded moxifloxacin composite film: A multifunctional bio-platform for the treatment of breast cancer

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: 1315, P. 138618 - 138618

Published: May 14, 2024

Language: Английский

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Research on lncRNA CTBP1-DT as a potential therapeutic target to regulate cell function in colorectal cancer

Discover Oncology, Journal Year: 2024, Volume and Issue: 15(1)

Published: June 12, 2024

Colorectal cancer, which originates from the human colon or rectum, is one of leading causes death worldwide. Timely diagnosis and interventional therapy can significantly improve prognostic survival colorectal cancer patients, making regular screening early detection essential.

Language: Английский

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Nanomedicine Marvels: Crafting the Future of Cancer Therapy with Innovative Statin Nano-formulation Strategies

Nanoscale Advances, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

The use of statins in cancer therapy is promising. Nanoformulations offer higher bioavailability, increased tumor concentration, better drug resistance reversal, and fewer side effects compared to free forms.

Language: Английский

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Oxaliplatin-loaded amphiphilic hyaluronic acid nanohydrogel formed via interfacial reactions enhances the therapeutic effect of targeted tumor

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 284, P. 138118 - 138118

Published: Nov. 26, 2024

Language: Английский

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