Balanced polymorphisms in gamete-binding genes are not associated with human infertility DOI Creative Commons
Michael W. Hart, Bernard J. Crespi,

Ken Seethram

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 15, 2024

ABSTRACT Genes expressed in gametes that mediate sperm interaction with the mammalian egg are of considerable interest to evolutionary biologists because evolution such genes can account for variation reproductive compatibility between mates and isolation species. The human orthologs also potential targets both contraception treatment infertility. One gene system particular is sperm-binding inner coat or zona pellucida ( Zp2, Zp3 ) their cognate protein mouse acrosome Zp3r ). Previous population genetic analyses humans pointed toward three balanced polymorphisms (one each ZP2, ZP3 , ZP3R as some form balancing selection fertility. We tested association using analysis couples seeking fertility assistance, but we could not reject null hypothesis no Our study was based on a small sample couples, data were sound: allele frequencies at those different from random expectation clinical sample. If an effect infertility exists it probably small. part old error annotation only recently discovered (after start participant recruitment this analysis), may our results, which argue against role humans.

Language: Английский

Headmen, shamans, and mothers: Natural and sexual selection for computational services DOI
Edward H. Hagen, Zachary H. Garfield, Aaron D. Lightner

et al.

Evolution and Human Behavior, Journal Year: 2025, Volume and Issue: 46(1), P. 106651 - 106651

Published: Jan. 1, 2025

Language: Английский

Citations

1
Crusaders, monks and family fortunes: evolutionary models of male homosexuality and related phenomena DOI
Petr Tureček, Jakub Fořt, Jaroslav Flegr

et al.

Proceedings of the Royal Society B Biological Sciences, Journal Year: 2025, Volume and Issue: 292(2042)

Published: March 1, 2025

The fraternal birth order effect (FBOE) is a well documented preponderance of older brothers among gay men. Until now, it has lacked proper formal treatment in light evolutionary theory. In this article, we propose two related mathematical models based on the rigorous application inclusive fitness concept. examine sibling rivalry and resource allocation within families. One assumes that laterborn's reproductive ability not compromised by manipulation leads to exclusive family resources firstborn. other model posits may lower direct zero. Both suggest FBOE arises primarily from brother's manipulation, as firstborn's increase, while mother's decreases, but vice versa. However, under certain conditions, mother should support an activity discourages division resources, extreme cases, younger homosexuality be best available strategy for his genes. also provide insight into cultural evolution primogeniture explain how between relatives could evolve before emergence substantial economic inequality.

Language: Английский

Citations

1
The DCIDE framework: systematic investigation of evolutionary hypotheses, exemplified with autism DOI Creative Commons
Adam Hunt, Adrian V. Jaeggi

Biological reviews/Biological reviews of the Cambridge Philosophical Society, Journal Year: 2025, Volume and Issue: unknown

Published: March 11, 2025

ABSTRACT Evolutionary explanations of mental disorders are a longstanding aim evolutionary psychiatry, but have suffered from complexities including within‐disorder heterogeneity and environmental effects contemporary societies obscuring possible ancestral functions. Studying the relevant processes human evolution directly is not possible, so hypotheses remained speculative, exaggerating “just‐so storytelling” critiques. This despite significant evidence existing in genetics, neuroscience epidemiology, all which bears some inferential relevance to hypotheses, often marshalled systematic way. To utilise this best investigate psychiatric (or other) traits we present novel framework synthesis analysis exemplify it by systematically reviewing related autism. In five stages “DCIDE framework” analysis, Description identifies trait explain Categorisation initially excludes verifiably non‐adaptive cases utilising neuroscience, factors. Integration then hones target for adaptive explanation considering age onset, effects, duration, prevalence sex differences, incorporating correlated visible selection. Depicted Evaluated their ability at hand, using standardised areas theoretically motivated principles (e.g. arising birth lasting life different plausible than adolescence receding adulthood). Competing can thus be compared sufficiency explaining wide range available evidence. DCIDE review autism, when Described with current diagnostic criteria, up 20% Categorise as non‐adaptive, primarily caused de novo mutations trauma. The remaining eligible explanation. For Integrating genetically phenotypes, high subclinical familial camouflaged female necessary. Depictions contrast intelligence by‐product hypothesis social niche specialisation “systemising” cognition. Evaluation, broad supports while fails predict various lines provides only most robust autism research date, first example how structure allow improved across conditions, may also adopted strengthen psychology more generally, countering just‐so storytelling cherry‐picking

Language: Английский

Citations

0
Consistency and Variation in Natural Selection on Personality Across 17 Countries DOI Creative Commons
Janko Međedović

Evolutionary Psychology, Journal Year: 2025, Volume and Issue: 23(1)

Published: Jan. 1, 2025

The effects of natural selection on personality traits are still understudied, which is in contrast with their importance for analyzing the evolution personality. In present research, we analyzed Big Five by estimating relations between characteristics and evolutionary fitness (reproductive success: i.e., number children) using World Values Survey wave 6 data ( N = 22,636; 17 countries). Using multilevel Poisson regression models random slopes, obtained a positive linear association conscientiousness reproductive success. We also detected nonlinear openness criterion measure: additional graphical ANOVA analyses showed that nonlinearity emerged from fact only individuals above average had lower effect sizes associations success were low. Finally, variation gradients (i.e., differences fixed model coefficients) across countries—coefficients both negative signs estimated extraversion, neuroticism, openness. This accordance state-dependent evolution, where environment viewed as an external state—the environment's moderating personality-fitness link may preserve inter-individual behavior within populations.

Language: Английский

Citations

0
The origins of darkness: An evolutionary-developmental integration of Dark traits with the HEXACO DOI Creative Commons
Anthony A. Volk, Andrew V. Dane,

Alexandra Puchalski

et al.

Evolution and Human Behavior, Journal Year: 2025, Volume and Issue: 46(3), P. 106689 - 106689

Published: April 19, 2025

Language: Английский

Citations

0
Schizophrenia genetic risk and labour market outcomes in the Finnish general population: Are schizophrenia-related traits penalised or rewarded? DOI Creative Commons

Aaro Hazak,

Johanna Liuhanen, Katri Kantojärvi

et al.

Comprehensive Psychiatry, Journal Year: 2025, Volume and Issue: unknown, P. 152600 - 152600

Published: April 1, 2025

Language: Английский

Citations

0
Balanced polymorphisms in gamete-binding genes are not associated with human infertility DOI Creative Commons
Michael W. Hart, Bernard J. Crespi,

Ken Seethram

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 15, 2024

ABSTRACT Genes expressed in gametes that mediate sperm interaction with the mammalian egg are of considerable interest to evolutionary biologists because evolution such genes can account for variation reproductive compatibility between mates and isolation species. The human orthologs also potential targets both contraception treatment infertility. One gene system particular is sperm-binding inner coat or zona pellucida ( Zp2, Zp3 ) their cognate protein mouse acrosome Zp3r ). Previous population genetic analyses humans pointed toward three balanced polymorphisms (one each ZP2, ZP3 , ZP3R as some form balancing selection fertility. We tested association using analysis couples seeking fertility assistance, but we could not reject null hypothesis no Our study was based on a small sample couples, data were sound: allele frequencies at those different from random expectation clinical sample. If an effect infertility exists it probably small. part old error annotation only recently discovered (after start participant recruitment this analysis), may our results, which argue against role humans.

Language: Английский

Citations

0