Investigation of the Relationship between Frailty, Successful Aging, and Physical Activity Levels in Older Individuals DOI Creative Commons
Burcu Akkurt, Nergis Yılmaz, Anil TOSUN

et al.

İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi, Journal Year: 2024, Volume and Issue: 24, P. 1270 - 1278

Published: Dec. 30, 2024

Aim: This study aimed to examine the relationship between frailty, successful aging, and physical activity levels in older individuals. Method: Data were collected from 99 volunteer participants aged ≥65. The questionnaire was delivered online via its Google Forms link. In study, Tilburg Frailty Indicator (TFI) used evaluate participants’ frailty levels, Successful Aging Scale (SAS) utilized determine their aging status, International Physical Activity Questionnaire-Short Form (IPAQ-SF) employed measure levels. Results: results of revealed a moderate, significant negative correlation TFI SAS total scores. Additionally, weak, positive found IPAQ-SF scores (s=0.982; p<0.001). A detected component score score. There significant, highly healthy lifestyle sub-parameter (s=-.0634; Conclusion: It has been determined that more active individuals exhibit both healthier lower frailty. women have be statistically frail less compared men. observed increases with age.

Language: Английский

Spine-specific sarcopenia: distinguishing paraspinal muscle atrophy from generalized sarcopenia DOI
Lukas Schönnagel,

Erika Chiaparelli,

Gastón Camino-Willhuber

et al.

The Spine Journal, Journal Year: 2024, Volume and Issue: 24(7), P. 1211 - 1221

Published: March 1, 2024

Language: Английский

Citations

10
Comparing the PRISMA-7 and a Modified Version (PRISMA-6) for Frailty Screening: Addressing Sex Bias in Community-Dwelling Older Adults DOI Creative Commons
Dietmar Ausserhofer, Angelika Mahlknecht, Verena Barbieri

et al.

Geriatrics, Journal Year: 2025, Volume and Issue: 10(1), P. 9 - 9

Published: Jan. 7, 2025

Background/Objectives: Frailty screening facilitates the identification of older adults at risk adverse health outcomes. The Program Research to Integrate Services for Maintenance Autonomy 7 (PRISMA-7) is a widely utilised frailty tool; however, concerns regarding its potential sex bias persist due item 2, which assigns point male sex. This study compared PRISMA-7 with modified version, PRISMA-6 (excluding 2), assess their suitability in South Tyrol, Italy. Objectives included evaluating impact 2 on classification and exploring feasibility as more equitable alternative. Methods: A cross-sectional survey 1695 community-dwelling aged ≥75 years was conducted Tyrol. assessed using both PRISMA-6. Sociodemographic, health, lifestyle data were collected examine associations classifications. Logistic regression applied identify predictors each tool. Agreement between assessed, internal consistency evaluated Cronbach's alpha. Results: prevalence 33.9% 27.0% classified men frail frequently than women (34.7% vs. 33.0%), while reversed this trend (men, 21.4%; women, 33.0%). Excluding improved (Cronbach's alpha: PRISMA-7, 0.64; PRISMA-6, 0.75) aligned classifications such age, status, physical activity. revealed significant differences but not Conclusions: introduces by overestimating men, whereas provides consistent findings highlight PRISMA-6's reliable tool unbiased screening. Future research should validate against established tools support integration into primary care settings.

Language: Английский

Citations

1
The relationship among socioeconomic status, social support and frailty: is there a gender difference? DOI Creative Commons
Pingsha Dong,

Xian-Qi Zhang,

Wenqiang Yin

et al.

Aging Clinical and Experimental Research, Journal Year: 2025, Volume and Issue: 37(1)

Published: April 2, 2025

This study aimed to determine the relationship among socioeconomic status, social support and frailty, its gender difference. Education income were combined indicate status. The Social Support Rating Scale (SSRS) was used measure level of support. Frailty measured by FRAIL Scale. Mediation effects analyzed using PROCESS 4.1 macro in SPSS version 26.0. Among 936 participants, status had a direct effect on frailty (effect = - 0.088, 95% CI: 0.142, 0.021). an indirect pathway for between 0.011, 0.023, 0.003), accounting 11.11% total effect. Stratified gender, we found that total, significant only female subsample. Overall, there association rural older adults, mediated this relationship. However, differences frailty. Specifically, correlation mediating role public health sector should focus adults with low lack support, taking targeted interventions avoid delay occurrence progress

Language: Английский

Citations

1
Influence of Sex and Gender on Musculoskeletal Conditions and How They Are Reported DOI
Laura L. Tosi, Kimberly Templeton, Andrew M. Pennington

et al.

Journal of Bone and Joint Surgery, Journal Year: 2024, Volume and Issue: 106(16), P. 1512 - 1519

Published: July 2, 2024

There is increasing evidence that musculoskeletal tissues are differentially regulated by sex hormones in males and females. The influence of hormones, addition to other sex-based differences such as anatomical alignment immune-system function, impact the prevalence severity disease well types injuries affect system outcomes prevention measures treatment. Literature specifically addressing related limited, underscoring imperative for both basic clinical research on this topic. This review highlights areas have implications bone cartilage health, including growth development, sports injuries, osteoarthritis, osteoporosis, frailty. It clear important aspects been understudied. Consideration how hormone therapy will prepuberty, during puberty, adults vital, yet little known. purpose article foster awareness interest advancing our understanding orthopaedic practice.

Language: Английский

Citations

7
The Genetic and Epigenetic Arms of Human Ageing and Longevity DOI Creative Commons
Elena Ciaglia, Francesco Montella, Valentina Lopardo

et al.

Biology, Journal Year: 2025, Volume and Issue: 14(1), P. 92 - 92

Published: Jan. 18, 2025

This proposed review aims to shed light on the major genetic and epigenetic contributions ageing process longevity of individuals. In this context, we summarize state knowledge most important variants, their interactions with environment, in achieving a healthy lifespan. We also explore contribution lifestyle influence non-heritable environmental factors (i.e., epigenetics). Accordingly, discuss role inflammageing as one targets overcome morbidity mortality older people for maintenance ageing. more integrated view will display not only underlying mechanisms at play but invites reader rethink both our attitudes toward age.

Language: Английский

Citations

0
Prevalence of Frailty and Associated Socioeconomic Factors in People Experiencing Homelessness in England: Cross-Sectional Analysis of Health Needs Survey Data DOI
Jo Dawes, Emmanouil Bagkeris, Kate Walters

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
Biology of sex differences in frailty and aging: Where are we? DOI Creative Commons
Beatrice Arosio, Emanuele Marzetti, Anna Picca

et al.

Experimental Gerontology, Journal Year: 2025, Volume and Issue: unknown, P. 112711 - 112711

Published: Feb. 1, 2025

Language: Английский

Citations

0
Symptoms of Orthostatic Hypotension and Drugs Affecting Autonomic Function are Associated with the Onset of Frailty in Community-Dwelling Persons Aged 80 Years and Above: A Prospective Observational Study DOI
Aziz Debain, Fien Loosveldt, Veerle Knoop

et al.

Drugs & Aging, Journal Year: 2025, Volume and Issue: unknown

Published: March 29, 2025

Language: Английский

Citations

0
Sex Bias in Frailty Screening: A Cross-Sectional Analysis of PRISMA-7 and the Clinical Frailty Scale in Primary Care DOI Creative Commons
Christian J. Wiedermann, Verena Barbieri, Dietmar Ausserhofer

et al.

Diagnostics, Journal Year: 2025, Volume and Issue: 15(7), P. 915 - 915

Published: April 2, 2025

Background/Objectives: Frailty screening is essential in primary care for the early identification of vulnerable older adults. PRISMA-7 a widely used tool, but Item 2 ("Are you male?") introduces potential sex bias and overestimates frailty men. PRISMA-6, modified version that excludes 2, might provide more equitable alternative. This study evaluates PRISMA-6's alignment with Clinical Scale (CFS) its impact on sex-specific classification. Methods: A cross-sectional was conducted 142 general practices across South Tyrol, including 9190 practice patients aged ≥75 years. assessed using PRISMA-7, CFS. Correlations between tools were calculated Kendall's Tau-b, whereas Fisher's z-test to compare differences alignment. The prevalence odds ratios stratified according age. Results: PRISMA-6 showed stronger correlation CFS (τ = 0.492) than 0.308, z -10.2, p < 0.001). effect pronounced men (z -9.8, 0.001), no difference observed women 0.00, 1.000). reduced detection rate closely aligned Conclusions: demonstrated improved compared PRISMA-7. However, use as tool requires prospective validation diverse settings. shows promise reliable should be considered future studies, particularly settings, while awaiting further validation.

Language: Английский

Citations

0
Frailty Predicts Mortality and Procedural Performance in Patients With Non‐Variceal Upper Gastrointestinal Bleeding DOI Creative Commons
Ali Jaan, Adeena Maryyum, Hassam Ali

et al.

JGH Open, Journal Year: 2025, Volume and Issue: 9(5)

Published: May 1, 2025

ABSTRACT Introduction Nonvariceal upper gastrointestinal bleeding (NVUGIB) is a common cause of hospitalization in the United States, with approximately 400 000 admissions annually and 5%–10% mortality rate. This study aimed to evaluate frailty's impact on NVUGIB outcomes. Methods We utilized 2019 National Readmission Database (NRD) identify adult patients (≥ 18 years) admitted principal diagnosis using ICD‐10‐CM codes. hospitalizations were stratified by frailty hospital risk score (HFRS) 5 or more as cut‐off for frailty. Multivariate regression analyses conducted analyze STATA 14.2 was used statistical testing. Results Among 218 647 admissions, 99 892 (45.69%) frail. Frail older, often female, had higher comorbidity burdens. They showed significantly greater in‐hospital (adjusted odds ratio [aOR] 5.64, 95% CI 4.94–6.44; p < 0.001), acute kidney injury (5.85), respiratory failure (6.93), septic shock (40.94), hemorrhagic (2.64), vasopressor use (4.36), mechanical ventilation (6.04), ICU admission (5.41). Although frail esophagogastroduodenoscopy (EGD) intervention (1.04; they less likely receive EGD within 24 h (0.75; 0.001). also rebleeding (1.18; 0.001) radioembolization (2.69; Length stay increased 2.30 days, total charges rose $28 518, discharge rehabilitation frequent (3.12; 0.01), 30‐day readmission (15.24% vs. 11.43%, HR 1.16; Conclusion Frailty independently predicts worse clinical outcomes resource NVUGIB. Recognizing may improve stratification guide tailored management strategies this high‐risk population.

Language: Английский

Citations

0