Advancements in the Esterification of Phytosterols Catalyzed by Immobilized Lipase DOI Open Access
Yuyang Zhang, Ying Yan, Zhiyuan Lin

et al.

Catalysts, Journal Year: 2025, Volume and Issue: 15(3), P. 225 - 225

Published: Feb. 27, 2025

Phytosterol exhibits cholesterol-lowering, cardiovascular-protecting, anti-inflammatory, and anticancer efficacies but has low bioavailability due to its high melting point poor solubility. Esterification with fatty acids enhances liposolubility, improving absorption utilization fivefold. Industrial production of phytosterol esters mainly relies on chemical synthesis, which faces challenges in separation, purification, quality assurance side reactions. Enzymatic featuring mild conditions, environmental friendliness, selectivity, gained attention from academia industry. Candida rugosa lipase (CRL) is widely utilized efficiency catalyzing the esterification phytosterol. Natural lipases are highly sensitive changes temperature pH difficult reuse continuous cycles; however, certain immobilization techniques can improve their catalytic activity stability. Furthermore, application immobilized synthesis be combined ultrasonic treatment enhance enzymatic catalysis. This paper reviews research progress by lipases, highlighting current future directions, thereby fostering further advancements field preparing through

Language: Английский

Efficient synthesis of isoamyl acetate in deep eutectic solvent utilizing in-situ aqueous phase immobilized lipase biocatalyst DOI
Yuyang Zhang, Qiujie Wang, Zhiyuan Lin

et al.

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 105963 - 105963

Published: Jan. 1, 2025

Language: Английский

Citations

1
Advancements in the Esterification of Phytosterols Catalyzed by Immobilized Lipase DOI Open Access
Yuyang Zhang, Ying Yan, Zhiyuan Lin

et al.

Catalysts, Journal Year: 2025, Volume and Issue: 15(3), P. 225 - 225

Published: Feb. 27, 2025

Phytosterol exhibits cholesterol-lowering, cardiovascular-protecting, anti-inflammatory, and anticancer efficacies but has low bioavailability due to its high melting point poor solubility. Esterification with fatty acids enhances liposolubility, improving absorption utilization fivefold. Industrial production of phytosterol esters mainly relies on chemical synthesis, which faces challenges in separation, purification, quality assurance side reactions. Enzymatic featuring mild conditions, environmental friendliness, selectivity, gained attention from academia industry. Candida rugosa lipase (CRL) is widely utilized efficiency catalyzing the esterification phytosterol. Natural lipases are highly sensitive changes temperature pH difficult reuse continuous cycles; however, certain immobilization techniques can improve their catalytic activity stability. Furthermore, application immobilized synthesis be combined ultrasonic treatment enhance enzymatic catalysis. This paper reviews research progress by lipases, highlighting current future directions, thereby fostering further advancements field preparing through

Language: Английский

Citations

0