Identification and Analysis of Sex-Biased MicroRNAs in Human Diseases DOI Open Access
Bitao Zhong, Chunmei Cui, Qinghua Cui

et al.

Genes, Journal Year: 2023, Volume and Issue: 14(9), P. 1688 - 1688

Published: Aug. 25, 2023

It is well known that significant differences exist between males and females in both physiology disease. Thus, it important to identify analyze sex-biased miRNAs. However, previous studies investigating sex miRNA expression have predominantly focused on healthy individuals or restricted their analysis a single Therefore, necessary comprehensively the miRNAs diseases. For this purpose, study, we first identified showing diseases based number of datasets. Then, performed bioinformatics for these Notably, our findings revealed women exhibit greater conserved are highly expressed compared men, implicated broader spectrum Additionally, explored enriched transcription factors, functions, associated with using set enrichment tool TAM 2.0. The insights gained from study could carry implications endeavors such as precision medicine possibly pave way more targeted tailored approaches disease management.

Language: Английский

Identification and Analysis of Sex-Biased MicroRNAs in Human Diseases DOI Open Access
Bitao Zhong, Chunmei Cui, Qinghua Cui

et al.

Genes, Journal Year: 2023, Volume and Issue: 14(9), P. 1688 - 1688

Published: Aug. 25, 2023

It is well known that significant differences exist between males and females in both physiology disease. Thus, it important to identify analyze sex-biased miRNAs. However, previous studies investigating sex miRNA expression have predominantly focused on healthy individuals or restricted their analysis a single Therefore, necessary comprehensively the miRNAs diseases. For this purpose, study, we first identified showing diseases based number of datasets. Then, performed bioinformatics for these Notably, our findings revealed women exhibit greater conserved are highly expressed compared men, implicated broader spectrum Additionally, explored enriched transcription factors, functions, associated with using set enrichment tool TAM 2.0. The insights gained from study could carry implications endeavors such as precision medicine possibly pave way more targeted tailored approaches disease management.

Language: Английский

Citations

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