Thyme, oregano, and rosemary: herbs and food supplements for the management of metabolic associated fatty liver disease
Hamza Elbouny,
No information about this author
Ayoub Amssayef,
No information about this author
Rania Benjamaa
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et al.
Nutrire,
Journal Year:
2025,
Volume and Issue:
50(1)
Published: Jan. 6, 2025
Language: Английский
Supplementation with Complex Phytonutrients Enhances Rumen Barrier Function and Growth Performance of Lambs by Regulating Rumen Microbiome and Metabolome
Juan Du,
No information about this author
Yuan Wang,
No information about this author
Shaohui Su
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et al.
Animals,
Journal Year:
2025,
Volume and Issue:
15(2), P. 228 - 228
Published: Jan. 16, 2025
Complex
phytonutrients
(CPS)
have
attracted
extensive
interest
due
to
their
anti-inflammatory
effects.
This
investigation
focused
on
the
impact
of
CPS
rumen
health
in
lambs
high-concentrate
diets,
emphasizing
growth
performance,
ruminal
fermentation,
epithelial
barrier
integrity,
metabolism,
and
microbial
communities.
A
total
54
lambs,
3
months
old
with
a
30.42
±
0.54
kg
body
weight,
were
randomly
assigned
three
treatment
groups,
six
replicates
per
replicate.
The
received
basal
diet
(the
ratio
concentrate
forage
was
75:25)
without
supplementation
(CON)
or
inclusion
2.5
g/kg
(CPS2.5)
5.0
(CPS5.0)
for
60
days.
groups
exhibited
increased
performance
improved
fermentation
parameters.
Mechanistically,
enhanced
function,
thereby
lowering
inflammation
inhibiting
overactivation
JNK/p38
MAPK
signaling
pathway,
effect
CPS5.0
better
than
that
CPS2.5.
Notably,
could
optimize
composition
microbiota
increase
levels
Ursolic
acid
other
metabolites.
strong
associations
between
bacteria
health-related
indicators
differential
metabolites
further
highlighted.
Our
findings
suggest
adding
lambs’
diets
has
widespread
positive
impacts,
including
reduced
mRNA
relative
expression
apoptosis-related
genes,
beneficial
changes
microbiome
metabolite
profiles.
Language: Английский
Antiviral activity of rosemary extract against Zika virus in human dermal fibroblasts
bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 31, 2025
Abstract
Flaviviruses
have
increasingly
emerged
and
re-emerged
in
recent
decades,
infecting
millions
of
people
annually.
Zika
virus
is
particularly
concerning
due
to
its
associated
pathological
complications,
including
microcephaly
newborns
Guillain-Barré
syndrome
adults,
posing
a
significant
threat
public
health.
Despite
efforts
made
by
the
scientific
community,
no
licensed
drugs
against
flaviviruses
been
developed.
Medicinal
plants
show
promise
as
novel
source
antiviral
agents,
they
possess
diverse
array
biologically
active
secondary
metabolites,
making
them
potential
candidates
for
therapeutic
use.
We
sought
investigate
rosemary
extract
(RE)
ZIKV
human
dermal
fibroblasts
(HFF-1
cells),
one
earliest
targets
infection.
was
treated
with
various
concentrations
RE
or
individual
major
polyphenols,
rosmarinic
acid
(RA),
carnosic
(CA),
carnosol
(CO),
remaining
infectivity
each
sample
measured
plaque
reduction
assay.
To
evaluate
impact
on
different
stages
replication
cycle,
HFF-1
cells
were
before,
during,
after
infection,
before
exerted
potent
activity
both
Vero
directly
acting
particles
Importantly,
significantly
inhibited
later
cycle
interfering
post-entry
mechanisms
within
host
cell.
Moreover,
RE-derived
polyphenols
CA
CO,
but
not
RA,
shown
reduce
infectivity.
Overall,
impairs
infection
vitro
interacting
prior
adsorption
processes
cycle.
This
study
provides
rigorous
evidence
indicating
development
an
agent,
warranting
further
investigation
into
underlying
inhibitory
effects
other
medically
important
flaviviruses.
Language: Английский
Effects of dietary polyphenols addition and oxygen concentration on digestion and absorption of fat in roast beef patties
Yu Chang,
No information about this author
Bowei Zhang,
No information about this author
Yüze Jia
No information about this author
et al.
Food Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown, P. 144280 - 144280
Published: April 1, 2025
Language: Английский
Characterization of Rosemary (Salvia rosmarinus) Essential Oil Obtained by Solvent-Free Microwave Extraction with Kombucha Tea (Anthriscus sylvestris L.) Produced by Adding Guava (Psidium guajava L.) Peel and Pulp
Tarım Bilimleri Dergisi,
Journal Year:
2025,
Volume and Issue:
31(1), P. 33 - 45
Published: Jan. 14, 2025
The
study
aimed
to
evaluate
the
potential
of
creating
a
functional
beverage
by
enriching
Anthriscus
sylvestris
(L.)
kombucha
production
with
guava
peel
and
pulp,
showcasing
variety
richness
product
formulations.
This
was
done
due
being
fermented
rich
in
various
bioactive
compounds
that
have
significant
effects
on
health
possibility
enhancing
diversity
through
different
Thus,
tea
physicochemical,
phytochemical,
antioxidant
activity,
sensory
evaluation
during
15-day
fermentation
period.
increased
acetic
acid
bacteria
yeast
count
indicates
is
viable
substrate
for
proliferation
Kombucha
symbiotic
microbes.
Adding
rosemary
oil
significantly
its
total
phenolic,
flavonoid,
vitamin
C
content
(P<0.05).
sylvestris-guava
has
antibacterial
properties
(zones
inhibition
18.32
17.31
mm
against
Staphylococcus
aureus
ATCC
25923
Escherichia
coli
25922,
respectively).
Moreover,
it
also
provided
an
inhibitory
effect
α-glucosidase
α-amylase,
enzymes
associated
diabetes.
DPPH,
ABTS*+,
FRAP,
CUPRAC,
ORAC
capacities
were
found
be
66.89-78.90%,
70.83-97.25%,
367-723.15
μmol
Trolox/mL,
381.40-460.45
486.50-737.50
respectively.
well-balanced
pleasant
properties.
These
findings
indicate
preparing
may
further
research
needed
determine
benefits.
Language: Английский