Emergence and Clonal Spread of Extended-Spectrum β-Lactamase-Producing Salmonella Infantis Carrying pESI Megaplasmids in Korean Retail Poultry Meat

Antibiotics, Journal Year: 2025, Volume and Issue: 14(4), P. 366 - 366

Published: April 1, 2025

Background/Objectives: Salmonella is a major cause of foodborne illnesses, with multidrug-resistant (MDR) strains posing significant threats to public health worldwide. This study investigated the prevalence and antimicrobial resistance (AMR) Salmonella, focusing on extended-spectrum β-lactamase (ESBL)-producing in retail poultry meat Korea. Methods: A total 300 samples were collected nationwide from markets. Multi-locus sequence typing, serotyping, susceptibility testing performed. Whole-genome sequencing (WGS) analysis was conducted against 28 representative ESBL-producing S. Infantis isolates identify genetic characteristics phylogenetic relationship. Results: detected 81.3% raw samples, ST32 being dominant serotype chicken (53.0%) Typhimurium ST19 predominant duck (39.0%). MDR identified 58.2% significantly higher rate than (p < 0.001). Notably, 75.3% carrying blaCTX-M-65. WGS geographically phenotypically revealed five clonal clusters, suggesting widespread dissemination across Korea’s supply chain. All contained pESI-like megaplasmid, multiple virulence genes, sequences highly identical plasmids reported United States, indicating potential international transmission. Conclusions: emphasizes urgent need for continuous surveillance responsible antibiotic use livestock under One Health framework. can provide an effective tool tracking AMR evolution spread within regions.

Language: Английский

Salmonella in Swiss and Imported Retail Chicken Meat - a Cross-Sectional Study

Journal of Food Protection, Journal Year: 2025, Volume and Issue: unknown, P. 100532 - 100532

Published: May 1, 2025

Language: Английский

Genetic Characteristics of Multidrug-Resistant Salmonella Isolated from Poultry Meat in South Korea

Microorganisms, Journal Year: 2024, Volume and Issue: 12(8), P. 1646 - 1646

Published: Aug. 11, 2024

Given the lack of genetic characterization data for multidrug-resistant (MDR) Salmonella in South Korean poultry, we analyzed 53 MDR strains from 1232 poultry meat samples (723 chicken, 509 duck) using whole-genome sequencing. Five serotypes were identified: S. Infantis (30/53, 56.6%), Enteritidis (11/53, 20.8%), Virchow (9/53, 17.0%), Agona (2/53, 3.8%), and Indiana (1/53, 1.9%). Sequence types (STs) included ST32, ST11, ST16, ST13, ST17, with three major clusters, each having two subclusters. Eight core genome sequence (cgSTs) 225993, 2268, 58360, 150996, 232041, 96964, 117577, 267045. had (117577, 267045) (225993, 58360) cgSTs, respectively, whereas showed allelic differences identical cgSTs. The subcluster was classified as chicken or duck. Twenty-eight antimicrobial resistance genes (ARGs), 10 plasmid replicons, 11 pathogenicity islands (SPIs), 230 virulence identified, showing distinct profiles by cluster subcluster. Infantis, primary Salmonella, carried IncFIB (pN55391) plasmid, 10–11 ARGs, nine SPIs, approximately 163 genes. Three (S. Enteritidis, Virchow) specific that can inform epidemiological surveillance.

Language: Английский