Applied Biochemistry and Microbiology, Journal Year: 2024, Volume and Issue: 60(4), P. 541 - 553
Published: July 27, 2024
Language: Английский
Applied Biochemistry and Microbiology, Journal Year: 2024, Volume and Issue: 60(4), P. 541 - 553
Published: July 27, 2024
Language: Английский
Talanta, Journal Year: 2025, Volume and Issue: 286, P. 127524 - 127524
Published: Jan. 7, 2025
Language: Английский
Citations
1Biosensors, Journal Year: 2025, Volume and Issue: 15(2), P. 85 - 85
Published: Feb. 4, 2025
Alzheimer’s disease (AD) is a prevalent neurodegenerative disorder and significant cause of dementia in elderly individuals, with growing prevalence our aging population. Extracellular amyloid-β peptides (Aβ), intracellular tau proteins, their phosphorylated forms have gained prominence as critical biomarkers for early precise diagnosis AD, correlating progression response to therapy. The high costs invasiveness conventional diagnostic methods, such positron emission tomography (PET) magnetic resonance imaging (MRI), limit suitability large-scale or routine screening. However, electrochemical (EC) analysis methods made progress detection due sensitivity, excellent specificity, portability, cost-effectiveness. This article reviews the EC biosensing technologies, focusing on protein blood (a low-invasive, accessible medium). then discusses various sensing platforms, including fabrication processes, (LOD), clinical potential show role these sensors transformers changing face AD diagnostics.
Language: Английский
Citations
1Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113172 - 113172
Published: Feb. 1, 2025
Language: Английский
Citations
1Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 254, P. 116204 - 116204
Published: March 16, 2024
Language: Английский
Citations
5Cancer Nanotechnology, Journal Year: 2024, Volume and Issue: 15(1)
Published: June 13, 2024
Abstract Extracellular vesicles (EVs) harbor several signaling molecules to maintain intercellular communication. Based on the exosomal cargo type, metabolic, genomic, and proteomic status of parent cells can be investigated. Due existence trivial levels target inside EVs, application accurate sensitive detection methods is mandatory. Here, we used an electrochemical immunosensor using a biotinylated monoclonal CD63 antibody as capturing element for EVs isolated from MDA-MB-231 cancer patients. Simultaneously, breast biomarker CA-15-3 was detected in sandwich method increase specificity. Data indicated linear dynamic range 2000–10000 EVs/µL lower limit quantification 2000 EVs/µL. data real sample analysis, differ according severity systemic content this factor. Pd-perovskite-based provides platform quick in-depth analysis cells.
Language: Английский
Citations
4Talanta, Journal Year: 2025, Volume and Issue: unknown, P. 128008 - 128008
Published: March 1, 2025
Language: Английский
Citations
0Chemical Papers, Journal Year: 2025, Volume and Issue: unknown
Published: April 10, 2025
Language: Английский
Citations
0Analytica Chimica Acta, Journal Year: 2025, Volume and Issue: 1357, P. 344067 - 344067
Published: April 14, 2025
Language: Английский
Citations
0Talanta, Journal Year: 2024, Volume and Issue: 276, P. 126250 - 126250
Published: May 11, 2024
Language: Английский
Citations
3Food Chemistry X, Journal Year: 2024, Volume and Issue: 24, P. 101879 - 101879
Published: Oct. 5, 2024
Thiram (THI) and asomate (ASO) are frequently detected agrochemicals in food samples due to widespread use as fungicides. However, their detection suffers from matrix interference, or the necessity of derivatization before measurement. Integrating HPLC with a post-column carbon dots (CDs)-enhanced chemiluminescence (CL) system makes it possible simultaneously separate selectively detect ASO THI fruit free deep purification. The studies on mechanisms demonstrated that CD intermediates anionic radical were responsible for remarkable CL enhancement THI. intensity is directly proportional fungicide concentration, ranges linearity being 5-250 μg·L
Language: Английский
Citations
3