Effectiveness of Herbal Medicines with Anti-Inflammatory, Antimicrobial, and Antioxidant Properties in Improving Oral Health and Treating Gingivitis and Periodontitis: A Systematic Review DOI Open Access
Giuseppina Malcangi, Angelo Michele Inchingolo, Lucia Casamassima

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(5), P. 762 - 762

Published: Feb. 21, 2025

Objectives: This systematic review investigates the effectiveness of natural extracts with anti-inflammatory properties for improving oral health, particularly in managing gingivitis and periodontal disease (PD). With PD being a major global health issue, exacerbated by microbial dysbiosis oxidative stress, integration phytochemicals herbal formulations into therapy offers promising avenue adjunctive treatments. Methods: A was conducted following PRISMA guidelines registered under International Prospective Register Systematic Reviews (ID: 641944). Databases, including PubMed, Scopus, Web Science, were searched between 18–24 December 2024, using Boolean keywords combining terms such as “herbal medicine”, “plant extracts”, “anti-inflammatory”, “periodontal therapy”. Studies involving animal models, vitro data, or non-peer-reviewed articles excluded. Results: Seventeen studies met inclusion criteria. Polyherbal single-component (e.g., Camellia sinensis, Punica granatum, Zingiber officinale, Rosmarinus officinalis) demonstrated comparable efficacy to conventional agents like chlorhexidine (CHX). rinses, camellia sinensis gels, granatum reduced inflammation, improved gingival showed antimicrobial properties, offering effective alternatives. Conclusions: Natural products, single polyherbal formulations, provide safe alternatives PD. Their anti-inflammatory, antimicrobial, antioxidant support their role alongside scaling root planning (SRP) therapy. However, further large-scale, long-term are needed standardize establish optimal protocols.

Language: Английский

New Strategies for the Extraction of Antioxidants from Fruits and Their By-Products: A Systematic Review DOI Creative Commons
Kaio Vinicius Lira da Silva Bastos,

Adriana Bezerra de Souza,

Alessandra Cristina Tomé

et al.

Plants, Journal Year: 2025, Volume and Issue: 14(5), P. 755 - 755

Published: March 1, 2025

This review highlights the recent advancements in extraction techniques for bioactive compounds from natural sources, focusing on methodologies that enhance both efficiency and sustainability. Techniques such as pressurized hot water (PHWE), solid-state fermentation (SSF), ionic liquids (ILs), electrohydrodynamic (EHD) methods have shown significant potential improving yields while preserving bioactivity of target compounds. These innovative approaches offer advantages over traditional methods, including reduced energy consumption, minimal environmental impact, ability to extract thermosensitive PHWE EHD are particularly effective extracting antioxidants compounds, whereas SSF provides an environmentally friendly alternative by valorizing agro-industrial waste. Ionic liquids, although promising complex phytochemicals, face challenges related scalability economic feasibility. The adoption these advanced represents a shift toward more sustainable cost-effective processes, promoting discovery utilization high-value also contribute development eco-friendly, strategies align with green chemistry principles regulatory standards. However, further research technological required address existing limitations ensure widespread application industrial pharmaceutical sectors.

Language: Английский

Citations

1
Effectiveness of Herbal Medicines with Anti-Inflammatory, Antimicrobial, and Antioxidant Properties in Improving Oral Health and Treating Gingivitis and Periodontitis: A Systematic Review DOI Open Access
Giuseppina Malcangi, Angelo Michele Inchingolo, Lucia Casamassima

et al.

Nutrients, Journal Year: 2025, Volume and Issue: 17(5), P. 762 - 762

Published: Feb. 21, 2025

Objectives: This systematic review investigates the effectiveness of natural extracts with anti-inflammatory properties for improving oral health, particularly in managing gingivitis and periodontal disease (PD). With PD being a major global health issue, exacerbated by microbial dysbiosis oxidative stress, integration phytochemicals herbal formulations into therapy offers promising avenue adjunctive treatments. Methods: A was conducted following PRISMA guidelines registered under International Prospective Register Systematic Reviews (ID: 641944). Databases, including PubMed, Scopus, Web Science, were searched between 18–24 December 2024, using Boolean keywords combining terms such as “herbal medicine”, “plant extracts”, “anti-inflammatory”, “periodontal therapy”. Studies involving animal models, vitro data, or non-peer-reviewed articles excluded. Results: Seventeen studies met inclusion criteria. Polyherbal single-component (e.g., Camellia sinensis, Punica granatum, Zingiber officinale, Rosmarinus officinalis) demonstrated comparable efficacy to conventional agents like chlorhexidine (CHX). rinses, camellia sinensis gels, granatum reduced inflammation, improved gingival showed antimicrobial properties, offering effective alternatives. Conclusions: Natural products, single polyherbal formulations, provide safe alternatives PD. Their anti-inflammatory, antimicrobial, antioxidant support their role alongside scaling root planning (SRP) therapy. However, further large-scale, long-term are needed standardize establish optimal protocols.

Language: Английский

Citations

0