Focus on Exercise Physiology and Sports Performance

Life, Journal Year: 2025, Volume and Issue: 15(1), P. 84 - 84

Published: Jan. 12, 2025

Exercise physiology is a crucial scientific discipline that explores the complex manner in which physical activity influences physiological responses and adaptations of human body [...]

Language: Английский

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Reversing Decline in Aging Muscles: Expected Trends, Impacts and Remedies

Journal of Functional Morphology and Kinesiology, Journal Year: 2025, Volume and Issue: 10(1), P. 29 - 29

Published: Jan. 11, 2025

Background: Age-related decline in musculoskeletal function is a significant concern, particularly Western countries facing demographic shifts and increased healthcare demands. This review examines the typical trajectories of deterioration with age evaluates effectiveness various interventions preventing or reversing these changes. Methods: The analyzes documented rates across multiple parameters, including muscle mass, Type II fiber reduction, decreased motor unit firing rates. It evidence from studies on targeted aimed at trends further decline. Results: suggests that multimodal interventions, strength training can effectively maintain improve physical aging adults. These have shown potential altering trajectory age-related function. Conclusions. findings this important implications for providers policymakers addressing challenges an population. By providing framework understanding through evidence-based offers strategies reducing costs improving quality life older

Language: Английский

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Special Issue: "Unlocking Athletic Potential: Exploring Exercise Physiology from Mechanisms to Performance"

Free Radical Biology and Medicine, Journal Year: 2025, Volume and Issue: 230, P. 48 - 49

Published: Jan. 29, 2025

Language: Английский

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Skeletal muscle growth to combat diabetes and obesity: the potential role of muscle‐secreted factors

Obesity, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 13, 2025

Abstract As the prevalence of obesity and metabolic disease continues to climb, need for effective therapeutic interventions remains high. The growth skeletal muscle (SkM) greatly influences systemic metabolism across whole body, making this tissue an important target combat rise dysfunction. Transgenic rodent models targeted SkM exhibit profound improvements in various remote tissues, including adipose liver. It is currently unclear how selective stimulation alters distant tissues; however, evidence suggests that muscle‐secreted factors may be involved. Here, we aim provide basic biomedical researchers with a summary current knowledge regarding regulated by anabolic pathways proteins SkM, as well their effects, implicate them whole‐body effects growth. In review, also identify several gaps field, future directions investigation, implications such resistance exercise pharmacology. image

Language: Английский

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CSE/H2S Signaling Pathways in Enhancing Muscle Function and Insulin Sensitivity During Exercise

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(4), P. 1741 - 1741

Published: Feb. 18, 2025

Exercise plays a crucial role in maintaining metabolic health, enhancing muscle function, and improving insulin sensitivity, thereby preventing diseases such as type 2 diabetes. Emerging evidence highlights the significance of cystathionine γ-lyase (CSE)/hydrogen sulfide (H2S) signaling pathway pivotal regulator molecular physiological adaptations induced by exercise. This review comprehensively examines biosynthesis metabolism H2S, its distribution different tissues, mechanisms which CSE/H2S influences contraction, repair, protein synthesis. Additionally, it explores how modulates pathways, glucose uptake, lipid metabolism, sensitivity. The potential H2S donors exercise supplements is also discussed, highlighting their ability to improve performance health. Current research advancements, including application multi-omics approaches, are reviewed provide deeper understanding complex networks involved. Furthermore, challenges future directions addressed, emphasizing need for further mechanistic studies clinical applications. underscores therapeutic targeting optimize benefits

Language: Английский

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The cyclic metabolic switching theory of intermittent fasting

Nature Metabolism, Journal Year: 2025, Volume and Issue: unknown

Published: March 14, 2025

Language: Английский

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Sculpting Success: The Importance of Diet and Physical Activity to Support Skeletal Muscle Health During Weight Loss with New Generation Anti-Obesity Medications

Current Developments in Nutrition, Journal Year: 2024, Volume and Issue: 8(11), P. 104486 - 104486

Published: Oct. 18, 2024

Language: Английский

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The Catabolic - Anabolic Cycling Hormesis Model of Health and Resilience

Ageing Research Reviews, Journal Year: 2024, Volume and Issue: unknown, P. 102588 - 102588

Published: Nov. 1, 2024

Language: Английский

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