Oxidative balance score is independently associated with reduced prevalence of sarcopenia among US adults with metabolic syndrome DOI Creative Commons

Miaohong Wang,

Huan Shi

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: April 8, 2025

Background This research seeks to explore the link between oxidative balance score (OBS) and sarcopenia in American adults with Metabolic Syndrome (MetS) using data from a national, population-based survey. Methods The study included 3,625 participants diagnosed Syndrome, all aged 20 years above, derived NHANES datasets spanning 1999–2006 2011–2018. OBS evaluation was based on 16 dietary 4 lifestyle elements. MetS diagnosis followed NCEP-ATP III guidelines, while identification FNIH standards. We employed multivariate logistic regression analyses delve into connections within cohort. Results Sarcopenia found 17.46% of participants. In models adjusted for variables, OBS, each showed significant inverse relationship among individuals [OBS: OR = 0.959, 95%CI: (0.948, 0.982), P trend 0.0005; OBS: 0.963, (0.939, 0.989), 0.0055; 0.860, (0.787, 0.939), 0.0011]. Higher scores were consistently linked decreased incidence (all < 0.05). Restricted cubic spline analysis confirmed that these relationships linear. impact age significant, benefits only observed those 40 older. Conclusions Maintaining diet rich antioxidants is both independently collectively lower occurrence MetS. These results bolster proposition developing OBS-centered preventive strategies patients, particularly

Language: Английский

Association between bone mineral density T-score and respiratory sarcopenia in older adults DOI Creative Commons
Ying Liu, Yutong Guo, Shun Xie

et al.

Frontiers in Medicine, Journal Year: 2025, Volume and Issue: 12

Published: March 4, 2025

Introduction Respiratory sarcopenia, characterized by reduced respiratory muscle mass and strength, is underdiagnosed in older adults. This cross-sectional study aimed to investigate the association between bone mineral density (BMD) T-score sarcopenia a Chinese population. Methods A total of 530 participants aged ≥60 years were recruited. was diagnosed based on peak expiratory flow rate (PEFR) cutoffs. BMD measured using dual-energy X-ray absorptiometry, assessed bioelectrical impedance analysis. Logistic regression models used analyze risk. Results Participants with exhibited lower T-score, appendicular skeletal index, trunk ratio, lung function parameters compared those without sarcopenia. The odds ratio (95% CI) for lowest tertile risk 4.52 (1.71–13.1) highest tertile. remained significant after adjusting confounding factors. Conclusion significantly associated an increased finding highlights importance monitoring early prevention strategies reduce incidence

Language: Английский

Citations

1
Episodic denervation as a driver of loss of skeletal muscle redox homeostasis and muscle weakness in sarcopenia: Possible amelioration by exercise DOI Creative Commons
Malcolm J. Jackson

Sports Medicine and Health Science, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

0
Pathological and Inflammatory Consequences of Aging DOI Creative Commons
Mario García‐Domínguez

Biomolecules, Journal Year: 2025, Volume and Issue: 15(3), P. 404 - 404

Published: March 12, 2025

Aging is a complex, progressive, and irreversible biological process that entails numerous structural functional changes in the organism. These affect all bodily systems, reducing their ability to respond adapt environment. Chronic inflammation one of key factors driving development age-related diseases, ultimately causing substantial decline abilities older individuals. This persistent inflammatory state (commonly known as “inflammaging”) characterized by elevated levels pro-inflammatory cytokines, an increase oxidative stress, perturbation immune homeostasis. Several factors, including cellular senescence, contribute this milieu, thereby amplifying conditions such cardiovascular disease, neurodegeneration, metabolic disorders. Exploring mechanisms chronic aging essential for developing targeted interventions aimed at promoting healthy aging. review explains strong connection between inflammation, highlighting potential therapeutic approaches like pharmacological treatments, dietary strategies, lifestyle changes.

Language: Английский

Citations

0
Oxidative balance score is independently associated with reduced prevalence of sarcopenia among US adults with metabolic syndrome DOI Creative Commons

Miaohong Wang,

Huan Shi

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: April 8, 2025

Background This research seeks to explore the link between oxidative balance score (OBS) and sarcopenia in American adults with Metabolic Syndrome (MetS) using data from a national, population-based survey. Methods The study included 3,625 participants diagnosed Syndrome, all aged 20 years above, derived NHANES datasets spanning 1999–2006 2011–2018. OBS evaluation was based on 16 dietary 4 lifestyle elements. MetS diagnosis followed NCEP-ATP III guidelines, while identification FNIH standards. We employed multivariate logistic regression analyses delve into connections within cohort. Results Sarcopenia found 17.46% of participants. In models adjusted for variables, OBS, each showed significant inverse relationship among individuals [OBS: OR = 0.959, 95%CI: (0.948, 0.982), P trend 0.0005; OBS: 0.963, (0.939, 0.989), 0.0055; 0.860, (0.787, 0.939), 0.0011]. Higher scores were consistently linked decreased incidence (all < 0.05). Restricted cubic spline analysis confirmed that these relationships linear. impact age significant, benefits only observed those 40 older. Conclusions Maintaining diet rich antioxidants is both independently collectively lower occurrence MetS. These results bolster proposition developing OBS-centered preventive strategies patients, particularly

Language: Английский

Citations

0