Circulating miRNAs involved in the immune response of the European seabass (Dicentrarchus labrax)
Fish & Shellfish Immunology,
Journal Year:
2025,
Volume and Issue:
160, P. 110232 - 110232
Published: Feb. 24, 2025
Understanding
the
immune
response
in
fish
through
transcriptomic
and
microRNA
(miRNA)
profiling
may
unlock
critical
insights
into
disease
resistance
mechanisms.
The
objective
of
present
study
was
to
examine
modulation
European
seabass
(Dicentrarchus
labrax)
following
bacterial
infection
vaccination.
Therefore,
sequencing
circulating
miRNA
isolated
from
blood
serum
3'UTR
transcriptome
head
kidney
conducted.
In
infected
19
miRNAs
were
found
be
differentially
expressed.
This
included
two
novel
exhibiting
high
levels
fish.
Regarding
vaccination,
three
specific
have
been
identified
that
demonstrated
a
substantial
increase
expression.
Two
them,
miR-216b
miR-30a-5p,
documented
possess
capacity
delay
progression
viral
infections.
analysis
revealed
no
significant
enrichment
down-regulated
transcripts.
However,
there
up-regulated
transcripts
related
ribosome
biogenesis
protein
processing.
vaccinated
did
not
demonstrate
enrichment.
Down-regulated
genes
on
other
hand
involved
cytoskeleton
organization
apoptosis,
indicating
cellular
disruption
might
potential
hindrance
effective
immunity.
Overall,
these
results
provide
first
regulation
host
responses
pathogen
Moreover,
detection
total
13
differential
expressed
miRNAs,
including
regulators
innate
immunity-related
such
as
Toll-like
receptor
18,
suggests
for
play
role
post-transcriptional
control
defenses.
Language: Английский
Modern biotechnological strategies for vaccine development in aquaculture – Prospects and challenges
Vaccine,
Journal Year:
2022,
Volume and Issue:
40(41), P. 5873 - 5881
Published: Sept. 1, 2022
Language: Английский
Antiparasitic approaches and strategies in European aquaculture, with emphasis on Mediterranean marine finfish farming: Present scenarios and future visions
Reviews in Aquaculture,
Journal Year:
2023,
Volume and Issue:
16(2), P. 622 - 643
Published: Sept. 12, 2023
Abstract
Parasitic
infections
can
be
occasionally
severe
in
the
European
marine
aquaculture
industry,
including
Mediterranean
region,
as
they
incur
considerable
financial
losses.
Due
to
lack
of
commercial
vaccines,
therapeutic
approaches
seem
only
measure
battle
parasitic
outbreaks.
Integrated
strategies
and
increased
resilience
hosts,
may
limit
some
degree
level
infestation.
Ectoparasitic
therapy
is
traditionally
based
on
baths,
with
few
exceptions.
Several
antiparasitic
compounds
have
been
registered
aquatic
medicine
combat
mainly
salmon
sea
lice;
however,
them
are
readily
used
against
fish
parasites.
Formalin
less
commonly
hydrogen
peroxide
baths
applied
ectoparasites
region.
Most
anti‐lice
antiparasitics
limited
potential
perhaps
due
their
adverse
environmental
impact.
Future
therapies
parasites
will
rely
effective
substances
ensuring
consumer,
animal,
welfare.
Ideally,
dietary
such
praziquantel
exhibiting
mild
impact
high
efficacy
a
wide
range
pathogens
should
adopted.
Moreover,
combined
integrated
pest
management,
involving
various
management
practices
use
chemicals,
priority
for
specific
The
information
presented
this
review
guide
future
research
promote
prudent
parasite
control
Mediterranean‐farmed
fish.
Language: Английский
Nelumbo nucifera synthesized selenium nanoparticles modulate the immune-antioxidants, biochemical indices, and pro/anti-inflammatory cytokines pathways in Oreochromis niloticus infected with Aeromonas veronii
Fish & Shellfish Immunology,
Journal Year:
2023,
Volume and Issue:
144, P. 109287 - 109287
Published: Dec. 12, 2023
Language: Английский
Systemic and mucosal immune responses in red tilapia (Oreochromis sp.) following immersion vaccination with a chitosan polymer-based nanovaccine against Aeromonas veronii
Fish & Shellfish Immunology,
Journal Year:
2024,
Volume and Issue:
146, P. 109383 - 109383
Published: Jan. 19, 2024
Language: Английский
Effect of Pseudomonas stutzeri F2 on rearing water quality and growth, innate immunity, visceral morphology and gut microbiota structure of juvenile spotted seabass (Lateolabrax maculatus)
Weilai Fu,
No information about this author
Peifeng Duan,
No information about this author
Qiang Wang
No information about this author
et al.
Aquaculture Reports,
Journal Year:
2023,
Volume and Issue:
30, P. 101536 - 101536
Published: March 23, 2023
Previous
reports
on
the
effects
of
probiotics
farmed
fish
have
focused
more
dietary
supplementation,
and
this
study
evaluated
Pseudomonas
stutzeri
F2
supplementation
in
rearing
water
juvenile
spotted
seabass
(Lateolabrax
maculatus).
Different
from
control
group
(T0),
where
ammonia
nitrogen
levels
were
reduced
by
exchange
circulation
system,
T1
T2
groups
supplemented
with
low
(3.0
×
103
CFU/mL)
high
105
concentrations
P.
ability
to
remove
nitrite,
respectively.
After
33
d
rearing,
weight
gain
rate,
specific
growth
feed
utilization
survival
rate
experimental
significantly
improved
(p
<
0.05).
activated
superoxide
dismutase
(SOD),
lysozyme
(LZM)
catalase
(CAT)
activities
serum
seabass;
increased
glutathione
peroxidase
(GSH-Px)
activity
liver
while
decreasing
malondialdehyde
(MDA)
levels.
Microscopic
observation
tissue
sections
revealed
muscle
thickness
mucosal
fold
height
midgut.
The
changes
gut
microbiota
16
S
rRNA
gene
sequencing
a
significant
decline
relative
abundance
Proteobacteria
(phylum)
Photobacterium
(genus)
groups.
Aeromonas
veronii
challenge
test
assess
disease
resistance
found
that
was
highest.
Our
showed
3.0
CFU/mL
performance
seabass,
innate
immunity,
microbiota,
enhanced
A.
veronii,
providing
new
idea
for
application
probiotics.
Language: Английский
The therapeutic role of Azadirachta indica leaves ethanolic extract against detrimental effects of Aeromonas veronii infection in Nile tilapia, Oreochromis niloticus
Fish Physiology and Biochemistry,
Journal Year:
2024,
Volume and Issue:
50(4), P. 1445 - 1460
Published: May 25, 2024
Language: Английский
New Challenges and Achievements in Mediterranean Fish Health Management
Bulletin of the European Association of Fish Pathologists,
Journal Year:
2024,
Volume and Issue:
unknown
Published: May 27, 2024
The
European
seabass
(
Dicentrarchus
labrax
)
and
gilthead
seabream
Sparus
aurata
are
key
species
in
marine
aquaculture,
cultivated
both
EU
North
African/Levant
Mediterranean
regions.
Production
disparities
between
these
areas
emphasize
a
significant
reliance
on
trade
for
juveniles,
feed,
other
resources,
posing
notable
biosecurity
risks.
Addressing
shared
health
concerns
across
the
requires
regional
approach
to
ensure
successful
management.
A
recent
workshop
delved
into
pivotal
topics,
including
insights
from
concluded
Horizon
2020
projects,
effectiveness
of
nutraceuticals
combating
parasitic
infections,
legal
considerations
surrounding
autogenous
vaccines,
updated
knowledge
betanodavirus
measures
aquaculture.
Discussions
also
explored
upcoming
challenges
such
as
sustainability
cage-based
production,
impact
climate
change,
enhancing
diagnostic
capabilities,
fortifying
measures,
advocating
education,
fostering
networking
opportunities.
Language: Английский
Evaluating the effectiveness of an autogenous vaccine to prevent motile Aeromonas septicaemia in striped catfish (Pangasianodon hypophthalmus) formulated by using DNA fingerprints for bacterial inclusion
Fish & Shellfish Immunology,
Journal Year:
2024,
Volume and Issue:
155, P. 110013 - 110013
Published: Nov. 5, 2024
Language: Английский