The mitochondrial genome sequence of Manchurian Hare ( Lepus mandshuricus ) DOI Creative Commons
Lin Chen, Jiale Fan, Suying Bai

et al.

Mitochondrial DNA Part B, Journal Year: 2024, Volume and Issue: 9(9), P. 1254 - 1257

Published: Sept. 1, 2024

The Manchurian hare (

Language: Английский

Chromosome-level reference genome assembly for the mountain hare (Lepus timidus) DOI Creative Commons
Zsófia Fekete, Dominic Absolon, Craig T. Michell

et al.

Peer Community Journal, Journal Year: 2025, Volume and Issue: 5

Published: Jan. 24, 2025

Language: Английский

Citations

1
Exploring mitonuclear interactions in the regulation of cell physiology: insights from interspecies cybrids DOI Creative Commons
Kateryna Gaertner, Riikka Tapanainen, Sina Saari

et al.

Experimental Cell Research, Journal Year: 2025, Volume and Issue: unknown, P. 114466 - 114466

Published: Feb. 1, 2025

Language: Английский

Citations

1
Chromosome-level reference genome assembly for the mountain hare (Lepus timidus) DOI Creative Commons
Zsófia Fekete, Dominic Absolon, Craig T. Michell

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: June 10, 2024

Abstract We present here a high-quality genome assembly of male mountain hare ( Lepus timidus Linnaeus), from Ilomantsi, Eastern Finland, utilizing an isolated fibroblast cell line as the source for high quality DNA and RNA. Following previously published brown reference assembly, is second Finnish pilot species European Reference Genome Atlas (ERGA) initiative, collaborative effort to generate genomes biodiversity. The was assembled using 21× PacBio HiFi sequencing data scaffolded Hi-C chromosome structure capture approach. After manual curation, primary length 2,695,305,354 bp with N50 125,755,317 bp. largest scaffold 181 Mbp 127 Mbp, contributing consisting 85 scaffolds alternate 109 scaffolds. include 23 autosomes, numbered according their size, well X Y chromosomes, matching known karyotype. Telomeric regions were on at least one end 19 chromosomes. has degree completeness based BUSCO score (mammalia_odb10 database), Complete: 95.1 % [Single copy: 92.3 %, Duplicated: 2.7 %], Fragmented 0.8 Missing 4.1 %. mitochondrial sequenced separately. meets Earth BioGenome Project criteria reference-standard assembly. Compared previous pseudo-reference L. ssp. hibernicus Bell, rabbit genome, this new represents nominate subspecies species-specific chromosomal conformation. will provide solid foundation future genomic research Lagomorpha, including insights into basis adaptations snowy cold environments. Furthermore, it opens opportunities experimental analysis gene functions.

Language: Английский

Citations

1
The mitochondrial genome sequence of Manchurian Hare ( Lepus mandshuricus ) DOI Creative Commons
Lin Chen, Jiale Fan, Suying Bai

et al.

Mitochondrial DNA Part B, Journal Year: 2024, Volume and Issue: 9(9), P. 1254 - 1257

Published: Sept. 1, 2024

The Manchurian hare (

Language: Английский

Citations

0