InFo Neurologie + Psychiatrie, Journal Year: 2024, Volume and Issue: 26(12), P. 22 - 23
Published: Dec. 1, 2024
International Journal of Environmental Research and Public Health, Journal Year: 2024, Volume and Issue: 21(6), P. 774 - 774
Published: June 14, 2024
Brain fog is a condition that characterized by poor concentration, memory loss, decreased cognitive function, and mental fatigue. Although it generally known as long-term COVID-19 symptom, brain has also been reported to be caused many other diseases. Thus, necessary assess this in certain populations. This study aimed evaluate the reliability validity of Fog Scale Turkish population. We conducted two phases. In pilot including 125 participants, we confirmed suitability scale for analyses then exploratory (n = 230) confirmatory factor 343). The Cronbach’s alpha value 23-item was 0.966. addition, three-factor structure result analyses. These three factors are fatigue, impaired acuity, confusion. found participants previously diagnosed with had higher scores. finding indicates an important can accompany COVID-19. Furthermore, validated construct acceptable fit valid useful tool
Language: Английский
Citations
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International Journal of Environmental Research and Public Health, Journal Year: 2024, Volume and Issue: 21(8), P. 1076 - 1076
Published: Aug. 16, 2024
Background and objective: The impairments duration of PASC (post-acute sequelae COVID-19) symptoms in mental health have, to date, not been comprehensively examined. Our objective is provide longitudinal data on the Post-COVID patients identify risk protective factors associated with a severe or prolonged course. Methods: 265 outpatient centre University Hospital Erlangen was assessed 17.1 (T0) 22.5 months after infection (T1). An online survey validated questionnaires for (Post-COVID Syndrome Score), depression (Patient Health Questionnaire-9), somatic Questionnaire-15), anxiety (Generalized Anxiety Disorder-7), fatigue (Fatigue Severity Scale) Post-Exertional Malaise (PEM) (DePaul Screening) conducted home environment. Results: In total, 80% experienced at follow-up. Clinically relevant depression, persistent symptoms, were reported by 55.8%, 72.5%, 18.9% 89.4% patients, respectively. Depressive, symptom severity decreased significantly over time; PEM remained an unchanged high level. factor higher scores older age; prior psychiatric illness treated psychotherapy more depressive, somatic, symptoms. longer between acute initial presentation centre. Conclusions: findings align previous research, claiming syndrome, lasting infection. In-depth assessment implications needed planning services disease prevention.
Language: Английский
Citations
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JRSM Open, Journal Year: 2024, Volume and Issue: 15(7)
Published: July 1, 2024
Objectives To investigate long COVID (LC) symptoms self-reported via a digital application. Explore associations between various demographic factors and intensity of LC symptoms. Design A retrospective case series study. We analysed from 1008 individuals with November 30, 2020, March 23, 2022. Setting England Wales. Participants Individuals using the healthcare application in 31 post-COVID-19 clinics self-reporting Main outcome measures Highest reported symptoms, Results 109 symptom categories were identified, pain (26.5%), neuropsychological issues (18.4%), fatigue (14.3%) dyspnoea (7.4%) most prevalent. The increased by 3.3% per month since registration. Age groups 68–77 78–87 experienced higher (32.8% 86% higher, respectively) compared to 18–27 age group. Women 9.2% more intense than men, non-white 23.5% white LC. Higher education levels (national vocational qualification (NVQ) 3 NVQ 5) associated less (27.7%, 62.8% 44.7% less, least educated (NVQ 1–2). People deprived areas had those area. No significant association was found index multiple deprivation (IMD) decile number Conclusion Treatment plans must prioritise addressing prevalent symptoms; we recommend sustained support for clinics. Demographic significantly influence severity, underlining need targeted interventions. These findings can inform policies better manage
Language: Английский
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Brain Behavior & Immunity - Health, Journal Year: 2024, Volume and Issue: 42, P. 100889 - 100889
Published: Oct. 18, 2024
Patients with coronavirus disease 2019(COVID-2019) infections may still experience long-term effects, fatigue being one of the most frequent ones. Clinical research on long COVID in Chinese population after infection is comparatively lacking.
Language: Английский
Citations
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Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(23), P. 7124 - 7124
Published: Nov. 25, 2024
Long COVID-19 (LC) is a poorly understood, multifactorial condition that persists for at least three months following SARS-CoV-2 infection. The underlying pathophysiological mechanisms responsible the wide range of associated symptoms-including fatigue, brain fog, and respiratory issues-remain unclear. However, emerging evidence suggests reactivation latent viral infections, such as Epstein-Barr virus, cytomegalovirus, varicella-zoster may significantly contribute to complexity LC. These viruses can be reactivated by SARS-CoV-2, contributing chronic inflammatory state prolongs symptomatology. This review confirms potential involvement infections in LC examines whether these play an independent role or act synergistically with other factors. In addition, recent studies have highlighted persistence immune dysregulation key elements Our findings suggest preventative strategies, including vaccination antiviral treatments during acute phase COVID-19, show reducing risk preventing reactivation. tailored diagnostic therapeutic strategies targeting are urgently needed. Identifying biomarkers reactivation, particularly high-risk populations, could considered another effective strategy mitigate severity. Further research crucial better understand interactions between improve prevention treatment
Language: Английский
Citations
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Brain Sciences, Journal Year: 2024, Volume and Issue: 14(12), P. 1277 - 1277
Published: Dec. 19, 2024
Background/Objectives: Olfactory dysfunction (OD) is associated with a variety of neurologic deficits and impacts socialization decisions, mood, overall quality life. As common symptom comprising the long COVID condition, persistent COVID-19-associated olfactory (C19OD) may further impact presentations neuropsychiatric sequelae. Our study aims to characterize longitudinal burden depression, anxiety, symptoms in population C19OD. Methods: Individuals perceived C19OD completed psychophysical screening evaluation their sense smell using comprehensive Sniffin’ Sticks assessment. Only those validated OD were included this prospective for baseline one-year follow-up. Participants also PHQ-9, Beck Anxiety Inventory (BAI), questionnaires at each time point. Anxiety, prevalence was calculated compared between points Pearson’s chi-squared, Fisher’s exact, Wilcoxon rank sum tests. Results: Each evaluated reported by 13–49% cohort participants both follow-up, except seizure (0% follow-up) word-finding difficulty (61–68% follow-up). Word-finding focus difficulties most commonly symptoms. In total, 41% some level depression 38% while 29% 27% anxiety respective points. Conclusions: are risk developing conditions. These psychiatric sequelae repeated assessment, even nearly 2.5 years following initial COVID-19 diagnosis.
Language: Английский
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The Lancet Psychiatry, Journal Year: 2024, Volume and Issue: 11(9), P. 667 - 669
Published: July 31, 2024
Language: Английский
Citations
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International Journal of Neuroscience, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 11
Published: Aug. 29, 2024
Post coronavirus disease 2019 (COVID-19) pandemic, the widespread emergence and persistence of brain fog has led to a decline in people's productivity quality life. However, clinical characteristics COVID-19-associated are unclear, standardized assessments lacking. This study aims develop scale for assessment support practice research.
Language: Английский
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BMC Psychology, Journal Year: 2024, Volume and Issue: 12(1)
Published: Sept. 16, 2024
Abstract Introduction In addition to physical symptoms such as dyspnea, fatigue, post-exertional malaise, and pain, a subgroup of patients with Post-COVID-19 syndrome (Post-Acute Sequelae COVID-19, PASC) suffers from mental illnesses anxiety, depression, neurocognitive impairments. To date, there are no causal treatments available for PASC. While initial studies show that psychotherapy improves psychological symptoms, PASC-related psychosocial functioning, further research is needed evaluate the effectiveness psychotherapeutic treatment Methods analysis This study presents non-randomized controlled trial aimed at evaluating five-week multimodal inpatient psychosomatic program individuals experiencing PASC comorbid illness. A total 118 presented Post-COVID Center Universitätsklinikum Erlangen will be assigned intervention group receiving or control usual. The inclusion criteria diagnosis least one condition distress problems coping primary objective reduce ailments, including depression well deficits, address fatigue pain. core elements in individual settings, medical treatment, training, therapy, adapted individual’s capacity oriented towards concept pacing. After enrollment, participants undergo 6-month follow-up assess long-term results sustainability effects. Discussion examines illness comparison based on can contribute development evidence-based interventions complex needs Trial registration German Clinical Register (DRKS), retrospectively registered 15.02.2024 DRKSID DRKS00033562.
Language: Английский
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International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(20), P. 11040 - 11040
Published: Oct. 14, 2024
The European olive tree, Olea europaea L., and its polyphenols hold great therapeutic potential to treat neuroinflammation cognitive impairment. This review examines the evidence for anti-inflammatory neuroprotective actions of their in treatment long COVID neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s (PD), multiple sclerosis (MS). Key findings suggest that exhibit antioxidant, anti-inflammatory, neuroprotective, antiviral properties, making them promising candidates intervention, especially when formulated unique combinations. Recommendations future research directions include elucidating molecular pathways through mechanistic studies, exploring implications polyphenol supplementation, conducting clinical trials assess efficacy safety. Investigating synergistic effects with other agents addressing different targets is suggested further exploration. reviewed strengthens translational value conditions involving dysfunction emphasizes novelty new formulations.
Language: Английский
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