Field-Effect Transistor Based on Nanocrystalline Graphite for DNA Immobilization DOI Creative Commons
Bianca Ţîncu, Eugen Chiriac, Tiberiu Burinaru

et al.

Biomolecules, Journal Year: 2025, Volume and Issue: 15(5), P. 619 - 619

Published: April 25, 2025

In recent years, field-effect transistors (FETs) based on graphene have attracted significant interest due to their unique electrical properties and potential for biosensing molecular detection applications. This study uses FETs with a nanocrystalline graphite (NCG) channel detect DNA nucleobases. The exceptional electronic of NCG, its high surface area, enable strong π–π stacking interactions nucleobases, promoting efficient adsorption stabilization the biomolecules. direct attachment nucleobases NCG leads substantial changes in device’s characteristics, which can be measured real time assess binding sequence recognition. method enables highly sensitive, label-free detection, opening up new possibilities rapid genetic analysis diagnostics. Understanding between graphene-based materials is crucial advancing research biotechnology, paving way more accurate diagnostic tools.

Language: Английский

Cerebellar Pathology in Forensic and Clinical Neuroscience DOI
Azhagu Madhavan Sivalingam,

Darshitha D Sureshkumar

Ageing Research Reviews, Journal Year: 2025, Volume and Issue: unknown, P. 102697 - 102697

Published: Feb. 1, 2025

Language: Английский

Citations

0
Field-Effect Transistor Based on Nanocrystalline Graphite for DNA Immobilization DOI Creative Commons
Bianca Ţîncu, Eugen Chiriac, Tiberiu Burinaru

et al.

Biomolecules, Journal Year: 2025, Volume and Issue: 15(5), P. 619 - 619

Published: April 25, 2025

In recent years, field-effect transistors (FETs) based on graphene have attracted significant interest due to their unique electrical properties and potential for biosensing molecular detection applications. This study uses FETs with a nanocrystalline graphite (NCG) channel detect DNA nucleobases. The exceptional electronic of NCG, its high surface area, enable strong π–π stacking interactions nucleobases, promoting efficient adsorption stabilization the biomolecules. direct attachment nucleobases NCG leads substantial changes in device’s characteristics, which can be measured real time assess binding sequence recognition. method enables highly sensitive, label-free detection, opening up new possibilities rapid genetic analysis diagnostics. Understanding between graphene-based materials is crucial advancing research biotechnology, paving way more accurate diagnostic tools.

Language: Английский

Citations

0