Bidirectional relationship between depression and activities of daily living and longitudinal mediation of cognitive function in patients with Parkinson’s disease
Yue Xu,
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Durong Chen,
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Meiqi Dong
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et al.
Frontiers in Aging Neuroscience,
Journal Year:
2025,
Volume and Issue:
17
Published: Feb. 12, 2025
Objective
To
investigate
the
bidirectional
relationship
between
depression
and
activities
of
daily
living
(ADL)
in
Parkinson’s
disease
(PD)
patients
explore
mediating
role
cognitive
function
over
time.
Methods
Data
from
892
PD
Progression
Markers
Initiative
(PPMI)
database
were
included
this
study,
depression,
function,
ADL
measured
using
Geriatric
Depression
Scale
(GDS-15),
Montreal
Cognitive
Assessment
(MoCA),
Unified
Disease
Rating
Scale,
Part
II
(UPDRS
II)
respectively.
The
cross-lagged
panel
model
(CLPM)
was
employed
to
analyze
reciprocal
ADL.
Then,
we
explored
with
PD,
mediation
effect
test
carried
out
a
bias-corrected
nonparametric
percentile
bootstrap
approach.
Results
predicted
their
subsequent
(
β
=
0.079,
p
<
0.01),
also
0.069,
0.05),
In
addition,
Bootstrap
analysis
showed
that
played
significant
prediction
0.006,
0.074,
95%CI
0.001
~
0.014),
0.067,
0.013).
Conclusion
There
is
PD.
Furthermore,
found
mediates
exists
Interventions
aimed
at
enhancing
could
potentially
lessen
vicious
cycle
thus
improving
patient
quality
life
(QOL).
Language: Английский
Interaction effects of sleep duration and activities of daily living on depressive symptoms among Chinese middle-aged and older adult individuals: evidence from the CHARLS
Tianmeng Wang,
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Wenjin Han,
No information about this author
Caihua Wang
No information about this author
et al.
Frontiers in Public Health,
Journal Year:
2025,
Volume and Issue:
13
Published: March 12, 2025
Objectives
Evidence
on
the
combined
effect
of
sleep
duration
and
activities
daily
living
(ADL)
depressive
symptoms
is
scarce.
This
study
aimed
to
explore
interaction
effects
between
ADL
limitations
among
Chinese
individuals
aged
≥45
years.
Methods
Data
were
extracted
from
China
Health
Retirement
Longitudinal
Study
(CHARLS)
wave
2020.
Sleep
was
self-reported.
The
Center
for
Epidemiological
Studies
Depression
Scale
a
12-item
scale
employed
estimate
limitations,
respectively.
Logistic
regression
analysis
conducted
examine
symptoms.
Results
found
that
short
(OR
=
1.69,
95%
CI:
1.57–1.83),
long
0.87,
0.79–0.95),
[basic
(BADL),
OR
1.82,
1.66–2.01;
instrumental
(IADL),
1.88,
1.71–2.07]
associated
with
Furthermore,
synergistic
risk
identified
IADL
(RERI
1.08,
0.57–1.59)
or
BADL
1.13,
0.60–1.65).
Conversely,
antagonistic
observed
0.88,
0.39–1.38)
0.76,
0.25–1.27)
Conclusion
revealed
significant
interactions
symptoms,
suggesting
enhancing
ADL’s
function
ensuring
adequate
could
effectively
prevent
Language: Английский
The Potential of Artificial Intelligence in Predicting Post-Stroke Rehabilitation Outcomes: Statistical Analysis Considering Rivermead Motor Assessment and Activities of Daily Living Indicators and Selected Demographic Variables
Applied Sciences,
Journal Year:
2024,
Volume and Issue:
14(24), P. 11806 - 11806
Published: Dec. 17, 2024
Strokes
are
currently
the
third
most
common
cause
of
death
worldwide
and
leading
disability
in
people
over
50
years
age.
The
functioning
post-stroke
patients
depends
primarily
on
well-conducted
rehabilitation,
both
stationary
conditions
at
home.
aim
this
study
was
to
evaluate
functional
outcomes
after
ischemic
stroke
who
underwent
home
rehabilitation.
RMA
(Rivermead
Motor
Assessment)
ADL
(activities
daily
living)
scales
were
used
for
evaluation.
A
total
20
a
4-week
rehabilitation
program
Cracow.
In
studied
group,
showed
improvement
period.
Predictive
models
created
(Net1,
Net2,
Net3)
using
artificial
intelligence
algorithms,
including
regression
classification
methods.
analysis
results
indicate
that
best
predicting
indicators.
For
prediction
accuracy
indicator
94.4%,
which
is
significantly
higher
compared
other
RMA1-3
indicators
achieved
relatively
low
rates
38.9–44.4%.
contrast,
Net3,
high
accuracy,
achieving
89.1–91.3%
correct
results.
conclusions
suggest
combination
Net2
Net3
can
contribute
optimizing
process,
allowing
therapy
be
tailored
individual
needs
patients.
research
proves
it
possible
predict
effect
by
AI.
implementation
such
solutions
increase
effectiveness
particularly
through
personalization
dynamic
monitoring
patient
progress.
Language: Английский