Iron oxide nanoparticle-stabilized Pickering emulsion-templated porous scaffolds loaded with polyunsaturated fatty acids (PUFAs) for bone tissue engineering DOI

W. Aadinath,

T. S.,

Iniyan Saravanakumar

et al.

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(37), P. 9312 - 9324

Published: Jan. 1, 2024

Dietary intake of ω-3-polyunsaturated fatty acids (PUFAs) can significantly improve the expression levels alkaline phosphatase (ALP) and osteocalcin. However, PUFAs are hydrophobic highly sensitive to temperature, oxygen concentration, pH, ionic strength. Hence, it is challenging use as bioactive compounds for bone tissue engineering. Here, we encapsulated in liposomes their stability. The hydrodynamic size PUFA-loaded was found be 121.3 ± 35 nm. GC-MS analysis showed that encapsulation efficiency 19.9 3.4%. These were loaded into porous scaffolds prepared by polymerizing glycidyl methacrylate trimethylolpropane triacrylate monomers using Pickering emulsion polymerization technique. Oleic acid-coated iron oxide nanoparticles used stabilizing agent prepare these acrylate-based containing (P-Lipo-IO(GMA-TMPTA)). SEM micrographs confirmed nature presence well-adhered liposomes. An

Language: Английский

Investigating the differences in the optical properties and laser photoluminescence for chitosan films extracted from two different origins DOI Creative Commons
Ahmed R. Ghazy

The European Physical Journal Plus, Journal Year: 2025, Volume and Issue: 140(1)

Published: Jan. 29, 2025

Language: Английский

Citations

0

Innovation in Osteogenesis Activation: Role of Marine-Derived Materials in Bone Regeneration DOI Creative Commons
Maria Giovanna Rizzo, Marilena Briglia, Vincenzo Zammuto

et al.

Current Issues in Molecular Biology, Journal Year: 2025, Volume and Issue: 47(3), P. 175 - 175

Published: March 7, 2025

Marine-derived biomaterials are emerging as promising candidates for tissue regeneration due to their sustainability, biocompatibility, bioactivity, and unique chemical structure. This review provides an overview of different marine-derived inorganic organic materials, such calcium carbonate, magnesium salts, silica, polysaccharides, bioactive peptides, lipid-based compounds, effects in promoting osteogenesis. Specifically, the osteoinductive, osteoconductive, osteointegrative activities traditional innovative materials that influence key molecular pathways BMP/Smad Wnt/β-catenin signaling underlying bone formation will be evaluated. also prospects approaches, i.e., phage display technology, optimize peptides targeted regeneration. In context sustainable this suggests some interesting applications unusual able overcome limitations conventional ones stimulate cellular by activating specific pathways.

Language: Английский

Citations

0

A Roadmap Draft for the Development of Marine Regenerative Medicine in I.R. Iran DOI Creative Commons

Mahdi Mahmoudpour,

Iraj Nabipour

Bulletin de la Banque Méllié Iran., Journal Year: 2025, Volume and Issue: 27(3), P. 231 - 249

Published: Jan. 1, 2025

Language: Английский

Citations

0

Marine-based bioactive self-healing hydrogel with tunable properties for tissue engineering and regenerative medicine DOI

B. Karuppasamy,

Nimu Chand Reger, Shanmugam Munisamy

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 101, P. 106267 - 106267

Published: Oct. 8, 2024

Language: Английский

Citations

2

Innovative Marine‐Sourced Hydroxyapatite, Chitosan, Collagen, and Gelatin for Eco‐Friendly Bone and Cartilage Regeneration DOI
Hoda Elkhenany, Mariam Waleed Soliman, Diaa Atta

et al.

Journal of Biomedical Materials Research Part A, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 7, 2024

In recent years, the exploration of sustainable alternatives in field bone tissue engineering has led researchers to focus on marine waste byproducts as a valuable resource. These resources, often overlooked remnants various industries, exhibit rich composition hydroxyapatite, collagen, calcium carbonate, and other minerals essential complex framework structure. Marine by-products can emit gases such methane carbon dioxide, highlighting urgency repurpose these materials for innovative regeneration solutions, offering approach address environmental challenges while advancing medical science. Using discarded offers promising pathway development regenerative medicine. This review investigates distinctive properties byproducts, emphasizing their capacity be recycled effectively contribute rebuilding cartilage during processes. We also highlight compatibility resources with biological platelet-rich plasma (PRP), stem cells, exosomes, natural bioproducts, well nanoparticles (NPs) polymers. By using potential we simultaneously promote solutions skeletal engineering, initiating new era environmentally green biomedical research.

Language: Английский

Citations

2

Chitosan/hydroxyapatite hydrogels for localized drug delivery and tissue engineering: A Review DOI Creative Commons

Khashayar Khodaverdi,

Seyed Morteza Naghib, Masoud Mozafari

et al.

Carbohydrate Polymer Technologies and Applications, Journal Year: 2024, Volume and Issue: unknown, P. 100640 - 100640

Published: Dec. 1, 2024

Language: Английский

Citations

2

Marine-Derived Bioactive Ingredients in Functional Foods for Aging: Nutritional and Therapeutic Perspectives DOI Creative Commons
Youngji Han, Dong Hyun Kim, Seung Pil Pack

et al.

Marine Drugs, Journal Year: 2024, Volume and Issue: 22(11), P. 496 - 496

Published: Nov. 4, 2024

Aging is closely linked to various health challenges, including cardiovascular disease, metabolic disorders, and neurodegenerative conditions. This study emphasizes the critical role of bioactive compounds derived from marine sources, such as antioxidants, omega-3 fatty acids, vitamins, minerals, polysaccharides, in addressing oxidative stress, inflammation, disorders related aging. Incorporating these materials into functional foods not only provides essential nutrients but also delivers therapeutic effects, thereby promoting healthy aging mitigating age-related diseases. The growth global anti-aging market, particularly North America, Europe, Asia, underscores significance this study. review systematically analyzes current research, identifying key compounds, their mechanisms action, potential benefits, thus highlighting broad applicability marine-derived enhancing improving quality life populations.

Language: Английский

Citations

1

Iron oxide nanoparticle-stabilized Pickering emulsion-templated porous scaffolds loaded with polyunsaturated fatty acids (PUFAs) for bone tissue engineering DOI

W. Aadinath,

T. S.,

Iniyan Saravanakumar

et al.

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(37), P. 9312 - 9324

Published: Jan. 1, 2024

Dietary intake of ω-3-polyunsaturated fatty acids (PUFAs) can significantly improve the expression levels alkaline phosphatase (ALP) and osteocalcin. However, PUFAs are hydrophobic highly sensitive to temperature, oxygen concentration, pH, ionic strength. Hence, it is challenging use as bioactive compounds for bone tissue engineering. Here, we encapsulated in liposomes their stability. The hydrodynamic size PUFA-loaded was found be 121.3 ± 35 nm. GC-MS analysis showed that encapsulation efficiency 19.9 3.4%. These were loaded into porous scaffolds prepared by polymerizing glycidyl methacrylate trimethylolpropane triacrylate monomers using Pickering emulsion polymerization technique. Oleic acid-coated iron oxide nanoparticles used stabilizing agent prepare these acrylate-based containing (P-Lipo-IO(GMA-TMPTA)). SEM micrographs confirmed nature presence well-adhered liposomes. An

Language: Английский

Citations

0