Ecotoxicological Effects of Polystyrene Particle Mix (20, 200, and 430 µm) on Cyprinus carpio DOI Creative Commons
Ştefania Gheorghe,

Anca-Maria Pătraşcu,

Cătălina Stoica

et al.

Toxics, Journal Year: 2025, Volume and Issue: 13(4), P. 246 - 246

Published: March 26, 2025

Global consumption led to increased and persistent plastic pollution in aquatic environments, affecting biota. Polystyrene (PS) is a synthetic polymer one of the most widely used plastics. This study aims investigate acute chronic effects PS microplastics on Cyprinus carpio using an adapted OECD methodology. For test, was tested different particle sizes (20, 200, 430 µm), each at concentrations 0, 1, 10, 100 mg PS/L. Mortality clinical signs were monitored after 96 h exposure. No recorded. In mix particles µm) total concentration 1.2 PS/L for 75-day fish Mortality, biometric parameters, physiological indices, antioxidant enzyme activities, including catalase (CAT), glutathione reductase (GRed), S-transferase (GST), 7-ethoxyresorufin-O-deethylase (EROD), lipid peroxidation (MDA), hepatic enzymes (alanine aminotransferase—ALT aspartate aminotransferase—AST), vitellogenin (VTG), acetylcholinesterase (ACh), assessed. Fish exposed exhibited 40% change hepatosomatic indices 75 days. Additionally, induced oxidative stress organs. CAT activity fourfold intestine, GRed thirtyfold gonads, GST doubled brain. also gills but not statistically significant compared control. Lipid observed kidney (twofold increase) detected intestine; however, these changes significant. EROD by 15% control group, indicating amplification expression. The ALT AST nine tenfold VTG 47%, ACh showed more than 80% inhibition brain muscle. Furthermore, overall protein expression intestine liver group. Our revealed incidence severity microplastic freshwater emphasized urgent need prevention, monitoring, mitigation measures combat pollution.

Language: Английский

Ecotoxicological Effects of Polystyrene Particle Mix (20, 200, and 430 µm) on Cyprinus carpio DOI Creative Commons
Ştefania Gheorghe,

Anca-Maria Pătraşcu,

Cătălina Stoica

et al.

Toxics, Journal Year: 2025, Volume and Issue: 13(4), P. 246 - 246

Published: March 26, 2025

Global consumption led to increased and persistent plastic pollution in aquatic environments, affecting biota. Polystyrene (PS) is a synthetic polymer one of the most widely used plastics. This study aims investigate acute chronic effects PS microplastics on Cyprinus carpio using an adapted OECD methodology. For test, was tested different particle sizes (20, 200, 430 µm), each at concentrations 0, 1, 10, 100 mg PS/L. Mortality clinical signs were monitored after 96 h exposure. No recorded. In mix particles µm) total concentration 1.2 PS/L for 75-day fish Mortality, biometric parameters, physiological indices, antioxidant enzyme activities, including catalase (CAT), glutathione reductase (GRed), S-transferase (GST), 7-ethoxyresorufin-O-deethylase (EROD), lipid peroxidation (MDA), hepatic enzymes (alanine aminotransferase—ALT aspartate aminotransferase—AST), vitellogenin (VTG), acetylcholinesterase (ACh), assessed. Fish exposed exhibited 40% change hepatosomatic indices 75 days. Additionally, induced oxidative stress organs. CAT activity fourfold intestine, GRed thirtyfold gonads, GST doubled brain. also gills but not statistically significant compared control. Lipid observed kidney (twofold increase) detected intestine; however, these changes significant. EROD by 15% control group, indicating amplification expression. The ALT AST nine tenfold VTG 47%, ACh showed more than 80% inhibition brain muscle. Furthermore, overall protein expression intestine liver group. Our revealed incidence severity microplastic freshwater emphasized urgent need prevention, monitoring, mitigation measures combat pollution.

Language: Английский

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