Impact of sub-lethal Aclonifen intoxication on biochemical and stress markers on Oncorhynchus mykiss: an integrative assessment of multi-biomarker responses DOI

Reham Al Horani,

Demet Doğan

Toxicology Research, Journal Year: 2024, Volume and Issue: 14(1)

Published: Dec. 23, 2024

Abstract Aclonifen is a diphenyl ether herbicide being included in the list of priority substances. Nevertheless, data related to its sublethal effects on fish are limited. Therefore, present study has been carried out investigate toxic aclonifen juvenile Oncorhynchus mykiss following 24, 48, 72 and 96 hours application concentrations 12.7, 63.5 127 μg/L. The resulted altered blood biochemistry appearing as hyperglycemia, decreased cholesterol induced activities transaminases ALT AST. inhibition AChE brain, gill liver was unimportant revealing weak potential anticholinesterase. induction recorded for SOD, CAT, GPx GST accompanied with sustained elevation TBARS PC levels. It demonstrates both pro-oxidant oxidation lipid proteins resulting loss membrane integrity protein function. Hyperglycemic condition levels might be proposed general adaptive responses compensate increased energy demand. integrative assessment multi-biomarker shows concentration duration rise calculated indexes. SOD achieved maximum scores liver, respectively. Considering results, oxidative stress inducing anticholinesterase activity along disturbing impact were evidenced. Moreover, adverse affects observed after short term O. mykiss, risk may cause at population level aquatic ecosystems emphasizing importance pesticide regulations avoid impacts non-target species.

Language: Английский

Lambda-Cyhalothrin induced behavioural, neurotoxic and oxidative stress on vertebrate model Danio rerio (Hamilton-Buchanan 1822) DOI
Darshana Sharma, Raktim Sarmah,

Rimon Sarmah

et al.

Ecotoxicology, Journal Year: 2024, Volume and Issue: 33(7), P. 663 - 676

Published: June 3, 2024

Language: Английский

Citations

2
Mixture of pesticides based on dimethylamine and imidacloprid affects locomotion of adult zebrafish DOI Creative Commons

Lisiane Siqueira,

Amanda Carolina Cole Varela,

Suelen Mendonça Soares

et al.

Environmental Science and Pollution Research, Journal Year: 2024, Volume and Issue: 31(19), P. 28827 - 28834

Published: April 8, 2024

Numerous chemical compounds are found in aquatic environments; among them pesticides. Pesticides widely used worldwide, and this use has progressively increased recent decades, resulting the accumulation of potentially toxic surface waters. Dimethylamine-based herbicides (DBH) imidacloprid-based insecticides (IBI) have low soil absorption high water solubility, facilitating arrival these environments. In study, our objective was to analyze whether two pesticides, DBH IBI at environmentally relevant concentrations 320 μg/L for each compound, their mixtures impact behavioral endocrine parameters adult zebrafish, verifying effect pesticides on exploratory behavior social analyzing hormonal related stress. Acute exposure mixture reduced fish locomotion. alone combination did not affect cortisol levels exposed animals. Pesticides, when tested together, can cause different effects non-target organisms, evaluation is extremely important.

Language: Английский

Citations

0
Effects of pesticides on fish: An overview of evolution of bioassays and cutting edge technologies DOI
Rajib Majumder

Deleted Journal, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

Citations

0
Impact of sub-lethal Aclonifen intoxication on biochemical and stress markers on Oncorhynchus mykiss: an integrative assessment of multi-biomarker responses DOI

Reham Al Horani,

Demet Doğan

Toxicology Research, Journal Year: 2024, Volume and Issue: 14(1)

Published: Dec. 23, 2024

Abstract Aclonifen is a diphenyl ether herbicide being included in the list of priority substances. Nevertheless, data related to its sublethal effects on fish are limited. Therefore, present study has been carried out investigate toxic aclonifen juvenile Oncorhynchus mykiss following 24, 48, 72 and 96 hours application concentrations 12.7, 63.5 127 μg/L. The resulted altered blood biochemistry appearing as hyperglycemia, decreased cholesterol induced activities transaminases ALT AST. inhibition AChE brain, gill liver was unimportant revealing weak potential anticholinesterase. induction recorded for SOD, CAT, GPx GST accompanied with sustained elevation TBARS PC levels. It demonstrates both pro-oxidant oxidation lipid proteins resulting loss membrane integrity protein function. Hyperglycemic condition levels might be proposed general adaptive responses compensate increased energy demand. integrative assessment multi-biomarker shows concentration duration rise calculated indexes. SOD achieved maximum scores liver, respectively. Considering results, oxidative stress inducing anticholinesterase activity along disturbing impact were evidenced. Moreover, adverse affects observed after short term O. mykiss, risk may cause at population level aquatic ecosystems emphasizing importance pesticide regulations avoid impacts non-target species.

Language: Английский

Citations

0