Polyhedron, Journal Year: 2024, Volume and Issue: 265, P. 117303 - 117303
Published: Nov. 13, 2024
Language: Английский
Polyhedron, Journal Year: 2024, Volume and Issue: 265, P. 117303 - 117303
Published: Nov. 13, 2024
Language: Английский
Next research., Journal Year: 2024, Volume and Issue: unknown, P. 100086 - 100086
Published: Nov. 1, 2024
Language: Английский
Citations
1Heliyon, Journal Year: 2024, Volume and Issue: 10(3), P. e24617 - e24617
Published: Feb. 1, 2024
Chrozophora plicata has been extensively utilized in India for the management of numerous disorders. The effective Phytoconstituents derived from Ethyl Acetate Fraction [EAFCP] have identified as Camptothecin Agathisflavone, Rutin, Procynidine B, and Apigenin. These detected EAFCP through qualitative analysis using LC-Q-TOF-MS/MS. anti-inflammatory properties are yet to be determined. Therefore, aim this study was utilize a network pharmacology-based methodology predict potential therapeutic targets setting inflammation. identification inflammation followed by acquisition verified EAFCP. key against were found creating target-functional PPI network, GO studies conducted on core order assess essential signalling pathways involved effects A total 38 significant hub associated with EAFCP's identified. proteins retrieved docking investigation based findings, which aided anticipating interaction between components targets. vivo revealed that had notable efficiency decreasing paw edema induced carrageenan rats. evidence we gathered collectively offers clarification about activity EAFCP, is predominantly linked suppression Cox 1, 2 pathway. aforementioned findings highlight could
Language: Английский
Citations
0Bulletin of Experimental Biology and Medicine, Journal Year: 2024, Volume and Issue: 177(1), P. 39 - 43
Published: May 1, 2024
Language: Английский
Citations
0Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 309 - 333
Published: Nov. 1, 2024
Language: Английский
Citations
0Polyhedron, Journal Year: 2024, Volume and Issue: 265, P. 117303 - 117303
Published: Nov. 13, 2024
Language: Английский
Citations
0