Published: Jan. 1, 2024
Language: Английский
Arabian Journal of Chemistry, Journal Year: 2024, Volume and Issue: 17(10), P. 105958 - 105958
Published: Aug. 20, 2024
In this research work, we designed a smart biodegradable PEG-coated MnO2 nanoparticles conjugated with doxorubicin (PMnO2-Dox NPs) for dual chemo-photodynamic therapy and magnetic resonance imaging (MRI) application. This highly sensitive pH-responsive PMnO2-Dox NPs causes effective drug release under acidic pH environment. not only improves the efficacy of due to synergistic response as well improved MRI via boosting T1 contrast. Manifold characterization techniques have been employed materials investigation. Crystallography were performed by using XRD analysis, which confirmed tetragonal crystal structure an approximate crystallite size 20–30 nm. Surface morphology was SEM results indicated spherical asymmetric agglomerated nanocluster NPs. in vitro bioassay, anticancer activity tested against breast cancer (MCF-7) cell line MTT test. Moreover, it can also inhibit growth primary secondary cancers without light exposure. Results suggested that convenient treatment combined but address way towards comprehensive strategy application bright contrast agent after overcoming problem multidrug resistance (MDR) therapeutic analysis.
Language: Английский
Citations
3
Molecules, Journal Year: 2024, Volume and Issue: 29(9), P. 2049 - 2049
Published: April 29, 2024
Bilayer electrospun fibers aimed to be used for skin tissue engineering applications were fabricated enhanced cell attachment and proliferation. Different ratios of PHBV-PLLA (70:30, 80:20, 90:10 w/w) blends on previously formed PHBV membranes produce their bilayers. The characterized with FTIR, which conformed the characteristic peaks assigned both PLLA. surface morphology was evaluated using SEM analysis that showed random porous morphology. fiber diameter pore size measured in range 0.7 ± 0.1 µm 1.9 0.2 µm, respectively. tensile properties bilayers determined an electrodynamic testing system. Bilayers had higher elongation at break (44.45%) compared monolayers (28.41%) improved ultimate strength (7.940 MPa) monolayer (2.450 MPa). In vitro cytotoxicity each scaffolds via culturing MC3T3 (pre-osteoblastic line) membranes. Proliferation Alamar Blue assay days 3, 7, 14, images cells cultured taken addition bright field imaging visually show attachment. Fluorescent nuclear staining performed DAPI imaged inverted fluorescent microscope. bilayer shows high mechanical as well biocompatibility good proliferation attachment, showing potential substitute applications.
Language: Английский
Citations
2
Arabian Journal of Chemistry, Journal Year: 2024, Volume and Issue: 17(7), P. 105840 - 105840
Published: May 22, 2024
Magnetic mixed ferrites with high heating efficacy have attracted lots of attention as a complementary method for cancer treatment via magnetic hyperthermia therapy. In the present study, Cu0.5Zn0.5-xNixFe2O4 nanoparticles were synthesized sol–gel combustion method. The effects nickel substitution (x = 0.1, 0.2, 0.3, 0.4 and 0.5) on structural properties produced investigated. nanopowders studied X-ray diffraction (XRD), scanning electron microscopy (SEM), simultaneous thermal analysis (STA), Fourier-transform infrared spectroscopy (FTIR), Transmission (TEM), vibrating-sample magnetometry (VSM) techniques. results showed that saturation magnetization coercivity ZnCuFe2O4 strongly affected by in structure so decreased from 55.4 emu/g to 36.0 emu/g, whereas increased 87.9 Oe 156.4 Oe. addition, Cu0.5Zn0.4Ni0.1Fe2O4 sample increases 55 58.1 rise calcination temperature 400 700 °C, respectively. efficiency samples was investigated under different fields exhibits increase 37 °C 49.5 during 10 min exposure field frequency 200 kHz. specific absorption rate value calculated 53.1 W/g. With viscosity environment, is reduced. Despite this decrease, characteristics remained strong enough envision their usage agents hyperthermia.
Language: Английский
Citations
2
Journal of Alloys and Compounds, Journal Year: 2024, Volume and Issue: 1010, P. 177451 - 177451
Published: Nov. 7, 2024
Language: Английский
Citations
2
Ceramics International, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 1, 2024
Language: Английский
Citations
1
Journal of Materials Research and Technology, Journal Year: 2024, Volume and Issue: 33, P. 5987 - 6010
Published: Oct. 30, 2024
Language: Английский
Citations
1
Radiochimica Acta, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 19, 2024
Abstract Nanocrystalline calcium titanate (CaTiO 3 ) doped with cerium ions (0.02 mol%) was synthesized via hydrothermal method and its luminescent properties were studied for gamma dosimetry. For the samples, best response achieved after annealing at 700 °C 8 h. The synthesis confirmed XRD technique yielding cyrstallite size of 22 nm most intense peak (121). surface morphology scanning electron microscopy (SEM) grain 12 µm. strong IR absorptions appeared cm−1 712 cm −1 attributed to bending mode vibrations changing angle between Ti–O–Ti CaTiO :Ce respectively, as Fourier-Transform Infrared (FTIR) Spectroscopy. Thermoluminescent (TL) undoped samples by Mikrolab RA94 TLD Reader-Analyzer having heating rate 10 °C/s, absorbed doses 0–20 mGy from 137 Cs γ-source a dose 100 mSv/h. found values 662 keV photon-sensing parameters, i.e., mass attenuation coefficients ( μ / ρ ), mass-energy coefficient en effective atomic number photon interaction Z eff,PI total energy absorption eff,PEA 0.07030882 2 /g, 0.0280245 13.9 13.4 respectively. Thus, nanophosphor has shown excellent thermoluminescent dosimetric radiation sensing in selected range.
Language: Английский
Citations
0
Process Biochemistry, Journal Year: 2024, Volume and Issue: 148, P. 79 - 103
Published: Nov. 16, 2024
Language: Английский
Citations
0
Heliyon, Journal Year: 2024, Volume and Issue: 10(23), P. e40771 - e40771
Published: Dec. 1, 2024
Language: Английский
Citations
0
Published: Jan. 1, 2024
Language: Английский
Citations
0