IET Nanobiotechnology,
Journal Year:
2024,
Volume and Issue:
2024(1)
Published: Jan. 1, 2024
Mesenchymal
stem
cell
(MSC)
membrane‐coated
metal–organic
frameworks
(MOFs)
represent
an
innovative
approach
to
enhance
the
uptake
and
therapeutic
efficacy
of
copper‐based
MOFs
(Cu‐MOFs)
in
tumor
cells.
By
leveraging
natural
homing
abilities
biocompatibility
MSC
membranes,
Cu‐MOFs
can
be
effectively
targeted
sites,
promoting
increased
cellular
uptake.
This
coating
not
only
facilitates
superior
internalization
by
cancer
cells
but
also
augments
outcomes
due
enhanced
delivery
copper
ions.
In
vitro
studies
demonstrate
that
(MSC‐Cu‐MOFs)
significantly
improve
cytotoxic
effects
on
compared
uncoated
Cu‐MOFs.
novel
strategy
presents
a
promising
avenue
for
advancing
precision
effectiveness
treatment
modalities,
showcasing
potential
clinical
applications
oncology.
E3S Web of Conferences,
Journal Year:
2024,
Volume and Issue:
547, P. 03020 - 03020
Published: Jan. 1, 2024
We
explore
the
many
ways
biocompatible
nanomaterials
may
be
used
in
sustainable
biomedical
settings.
Quantum
dots
are
10
nm
size,
carbon
nanotubes
50
nm,
iron
oxide
nanoparticles
25
gold
20
and
silver
30
nm.
The
physicochemical
features
of
these
different
from
one
another.
These
encapsulate
therapeutic
substances,
according
to
drug
loading
evaluations;
for
example,
can
hold
15
mg/g
oxide,
12
silver,
18
nanotubes,
carbon,
quantum
dots.
Nanoparticles
(95%
vitality
after
24
hours),
(93%
viability),
(97%
(92%
(90%
viability)
highlight
biocompatibility
materials.
Fluorescence
intensities
1000
AU
nanoparticles,
980
1050
900
1100
were
observed
vivo
imaging
investigations,
further
demonstrating
potential
as
contrast
agents.
By
conducting
thorough
assessments
analyses,
this
study
reveals
how
create
long-term
applications,
such
molecular
targeted
delivery,
which
will
improve
healthcare
solutions
patient
outcomes.
IET Nanobiotechnology,
Journal Year:
2024,
Volume and Issue:
2024(1)
Published: Jan. 1, 2024
Mesenchymal
stem
cell
(MSC)
membrane‐coated
metal–organic
frameworks
(MOFs)
represent
an
innovative
approach
to
enhance
the
uptake
and
therapeutic
efficacy
of
copper‐based
MOFs
(Cu‐MOFs)
in
tumor
cells.
By
leveraging
natural
homing
abilities
biocompatibility
MSC
membranes,
Cu‐MOFs
can
be
effectively
targeted
sites,
promoting
increased
cellular
uptake.
This
coating
not
only
facilitates
superior
internalization
by
cancer
cells
but
also
augments
outcomes
due
enhanced
delivery
copper
ions.
In
vitro
studies
demonstrate
that
(MSC‐Cu‐MOFs)
significantly
improve
cytotoxic
effects
on
compared
uncoated
Cu‐MOFs.
novel
strategy
presents
a
promising
avenue
for
advancing
precision
effectiveness
treatment
modalities,
showcasing
potential
clinical
applications
oncology.