South African Medicinal Plants Traditionally Used for Wound Treatment: An Ethnobotanical Systematic Review

Plants, Journal Year: 2025, Volume and Issue: 14(5), P. 818 - 818

Published: March 5, 2025

Microbial contamination of chronic wounds complicates their treatment. Traditional knowledge systems and the diversity indigenous medicinal plants create a haven for traditional medicine practices in South Africa (SA). This systematic review aims to present comprehensive ethnobotanical report medicines used documented empirical wound healing studies SA. Google Scholar, PubMed, Medline EBSCOhost, Science Direct, Scopus were sourced using keywords/terminologies “South Africa”, “medicinal plants”, “traditional medicine” “indigenous”, “skin”, “wound”, “ethnobotany”, “survey”, “interview”, “treatment” different combinations. Relevant unpublished records retrieved from Global Electronic Thesis Database. The searching process identified 32,419 records, which 4005 screened. Following removal 1795 duplicates, remaining 2210 sources screened by title abstract, 133 full-text reports accessed evaluated. Plants traditionally wound-healing purposes comprised 222 species belonging 71 families, namely Asteraceae (predominantly Helichrysum species), Asphodelaceae, Fabaceae, Solanaceae, Euphorbiaceae. Plant organs remedies included leaves, roots, bark prepared as poultices, infusions, decoctions, gel/ointments/lotions, pastes. provides valuable reference future phytochemical pharmacological highlights need further research treat

Language: Английский

Antibacterial and Antioxidant Activities, Toxicity, and Physicochemical Properties of Crassocephalum montuosum (S Moore) Milne‐Redh and Crassocephalum picridifolium (DC) S Moore

Advances in Pharmacological and Pharmaceutical Sciences, Journal Year: 2024, Volume and Issue: 2024(1)

Published: Jan. 1, 2024

In traditional Congolese medicine, the plants Crassocephalum montuosum (CrasMon) and picridifolium (CrasPic) are used to treat bacterial gastroenteritis. present study, antibacterial antioxidant activities as well acute subacute toxicity of organic extracts from whole plant two investigated taxa were evaluated. Physicochemical parameters also determined, total phenolics, flavonoids, tannins assayed. The evaluated using disc diffusion, tube macrodilution, DPPH tests. Conversely, solution reactions, gravimetric tests, spectrophotometric tests generate physicochemical profiles, identify secondary metabolite groups, perform microdilution evaluate activities, respectively. OECD adapted assess toxicity. All showed activity against E. coli S. typhi strains with diameter zone inhibition (DZI) ranging 12 23 mm minimum inhibitory concentration (MIC): 15.625–125 μg·mL −1 . methanolic extract CrasPic most pronounced a DZI 21–23 MIC 15.625–62.5 high IC 50 (half maximal concentration) 11.6 21.8 , CrasMon showing activity. Both contain variety phytochemicals including coumarins, quinones, phenols, saponins, tannins, terpenoids. exhibits highest content phenolics (300 mg·GAE·g ), flavonoids (56 mg·QE·g (155 ). These have median lethal dose (LD ) > 5000 mg·kg no signs at 200 after 30 days oral administration Cavia porcellus ash was determined be 14.2% 15.8% (on dry weight basis), insoluble in hydrochloric acid exhibiting range 4.04%–5.03%. been demonstrated exhibit good least part, due presence phenolic compounds. may provide rationale for their use medicine

Language: Английский

Antioxidant Potential of Medicinal Plants in the Treatment of Scabies Infestation

Molecules, Journal Year: 2024, Volume and Issue: 29(22), P. 5310 - 5310

Published: Nov. 11, 2024

Oxidative stress, characterized by an overproduction of reactive oxygen species that overwhelm the body's physiological defense mechanisms, is a key factor in progression parasitic diseases both humans and animals. Scabies, highly contagious dermatological condition caused mite

Language: Английский