Metrnl plays a crucial role in the regulation of glycolipid metabolism

Metabolism and Target Organ Damage, Journal Year: 2025, Volume and Issue: 5(1)

Published: Jan. 25, 2025

An imbalance in the metabolism of glycolipids largely causes numerous metabolic diseases that negatively affect human health. Metrnl plays an important role glycolipid and regulates glucose lipid through multiple mechanisms. However, expression level related to remains controversial. can increase utilization by tissue cells reduce adverse effects a high-glucose environment on body; metabolism, it composition blood lipids, accumulation fat, promote browning white fat. The clinical efficacy exogenously administered recombinant needs be further investigated verified. This review presents overview Metrnl, emphasizing its association with diseases. It offers theoretical foundation for treatment metabolism-related conditions.

Language: Английский

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The Association Between Plasma Metrnl and Insulin Resistance Among Vietnamese Type 2 Diabetes Patients with or Without Dyslipidemia

Bratislavské lekárske listy/Bratislava medical journal, Journal Year: 2025, Volume and Issue: unknown

Published: March 10, 2025

Language: Английский

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Health and training-competition taxon categorization of body immersion and cold water swimming

Fizicka kultura, Journal Year: 2025, Volume and Issue: 00, P. 17 - 17

Published: Jan. 1, 2025

Immersion and swimming in cold water are an integral part of the human evolution, but also element legacy cultural religious heritage. It is life practice that becoming more popular due to recognition benefits it provides, both method training sports on land, water, as well terms a person's overall health, age lifespan. By identifying analyzing 128 articles from four scientific databases, several areas knowledge related effects stress, swimming, i.e. responses organic systems their co-adaptations, were determined. was determined empirical facts, theoretical generalizations, models established around large number facts interdisciplinary multidisciplinary nature (classification). In next step, they systematized into cognitive frameworks - taxa, axioms rich experience. Taxa named basis being "dozes" them, that: a) respiration circulation; b) inflammatory course; c) immune response; g) stress anxiety; d) aging; f) competitive abilities; e) prophylaxis; h) rehabilitation; z) methodological challenges; i) customs; j) habits. identifying, categorizing systematizing inter construct created for further study affirmations, encouraging practice, recovery, directing habits, theories healthy aging No less important immersion customs.

Language: Английский

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Cinnamon for Metabolic Diseases and Their Cardiovascular and Hepatic Complications: A Mechanistic Review

The American Journal of Chinese Medicine, Journal Year: 2024, Volume and Issue: 52(08), P. 2403 - 2421

Published: Jan. 1, 2024

Cinnamon is one of the world’s oldest and most popular spices, derived from inner bark several tree species genus Cinnamomum. During last two decades, cinnamon has demonstrated beneficial metabolic effects not only in animal experiments but also clinical trials. Even recent meta-analyses have shown protective on different components syndrome their complications. In 5 years, experimental studies unraveled intricate molecular mechanisms underlying antihypertensive, antihyperglycemic, lipid-lowering, weight-lowering, cardioprotective properties cinnamon. This review paper will discuss how its active components, particularly cinnamaldehyde, suppress inflammation oxidative stress, modulate mitochondrial dysfunction, regulate glucose uptake, insulin resistance, lipogenesis, beta-oxidation, Ca2+ signaling, other cellar events at level. Specifically, we delve into involved to provide a deeper insight can bring such effects. hopes encourage use settings, guide combination with drugs used treat based mechanism action, support concept complementary medicine for diseases.

Language: Английский

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