A Preliminary Evaluation of the Comparative Efficacy of Gel-Based and Oil-Based CBD on Hematologic and Biochemical Responses in Dogs

Veterinary Sciences, Journal Year: 2025, Volume and Issue: 12(4), P. 342 - 342

Published: April 7, 2025

Cannabidiol (CBD) has gained popularity in veterinary medicine for its potential to alleviate stress, pain, and inflammation dogs. However, oral administration is limited by hydrophobicity, variable absorption, extensive first-pass metabolism, which requires optimized delivery methods enhance efficacy. This study investigated the effects of daily supplementation CBD oil gel (each at 4 mg/kg), compared a placebo, over 14 days shelter dogs subjected solitary confinement-induced stress. Both formulations appeared safe under conditions, with no adverse on hematological biochemical parameters. Post-stress cortisol levels were significantly lower CBD-treated groups controls, CBD-infused showing pattern toward greater attenuation. Multivariate analysis revealed distinct blood profile shifts dogs, PCA loadings indicating associations between lymphocyte percentages IgG levels. These findings support gel-based as promising strategy stress modulation Further studies should explore pharmacokinetics long-term immune optimize applications.

Language: Английский

Effects of hemp-based polyunsaturated fatty acid supplementation on membrane lipid profiles and reproductive performance in Martina Franca jacks

Frontiers in Veterinary Science, Journal Year: 2025, Volume and Issue: 12

Published: April 16, 2025

This study evaluates the impact of dietary supplementation with hemp-based polyunsaturated fatty acids (PUFAs) on membrane lipid profiles and reproductive performance Martina Franca jacks. Over a 90-day period, twelve donkeys were divided into treatment group receiving hemp oil control standard diet. Semen blood samples collected analyzed at multiple time points for composition parameters. Results revealed that sperm motility improved significantly, increasing from 92.61% in to 96.63% by Day 60 (p = 0.05). Normal morphology also showed significant enhancement, rising 96.58% 98.85% 0.04). Conversely, gel-free semen volume decreased significantly group, 64.17 mL 28.20 < 0.0001). Lipidomic analyses indicated an increased proportion omega-3 PUFAs, such as eicosapentaenoic acid (EPA; 0.08% 0.20% 60, p 0.0001), membranes, alongside reduction peroxidation index (264.11 86.53 These changes suggest fluidity oxidative stability. findings underscore potential supplement enhance outcomes donkeys, broader implications livestock management.

Language: Английский

Pilot Investigation of Socio-Spatial Relationships in an Ex Situ White Rhino (Ceratotherium simum simum) Bachelor Group

Journal of Zoological and Botanical Gardens, Journal Year: 2024, Volume and Issue: 5(4), P. 774 - 787

Published: Dec. 6, 2024

Nonbreeding white rhino bulls are traditionally housed individually in zoos, but space limitations require the exploration of alternative techniques. There no studies group-housed bulls, and feasibility managing a bachelor group is unknown. Six (two each 3-, 5-, 8-yr-olds) 3.1 ha enclosure were observed for 30 min 2×/wk 20–31 wks. The 3-yr-olds relocated after first 20 weeks. Rhino location, nearest neighbor, aggressive behaviors, dominance interactions recorded. was evidence habitat spatial segregation. 3- 5-yr-olds grouped together by age; 8-yr-olds did not associate as much younger rhinos. Aggressive vocalizations physical aggression infrequent (range 0–1.5/h/bull 0–1/h/bull, respectively). Eight-year-olds displayed received most; three-year-olds most. After removed, usage social proximity remaining change. behaviors increased, 0.18–3.1/h/bull) remained more frequent than 0.18–0.73/h/bull). highest-ranking 8-yr-old engaged altercations least. shared space, use deterred injury. These findings indicate that management feasible large with young bulls.

Language: Английский