Effect of basic fibroblast growth factor on hypoxia-inducible factor (HIF)-1α expression (Exp) and HIF-1 transcription in breast Cancer cell through PI-3 K Akt signaling

Cytokine, Journal Year: 2025, Volume and Issue: 187, P. 156859 - 156859

Published: Jan. 17, 2025

Language: Английский

Research Progress on the Therapeutic Mechanisms of Stigmasterol for Multiple Diseases

Molecules, Journal Year: 2025, Volume and Issue: 30(9), P. 1874 - 1874

Published: April 23, 2025

Stigmasterol is a plant-derived phytosterol that has attracted considerable attention because of its diverse biological activities and potential therapeutic applications. In this review, the chemical properties, biosynthesis, effects stigmasterol are exhaustively summarized. Furthermore, anti-inflammatory, antioxidant, anticancer, neuroprotective, hypolipidemic have been discussed. Findings from various in vitro vivo studies revealed treating diseases, including cancer, diabetes, neurological disorders, inflammatory conditions. The mechanisms underlying these also discussed, particularly emphasizing regulation key signaling pathways molecular targets, to further clarify role stigmasterol. This review would provide reference for exploring utility as agent, thereby contributing improvement human health.

Language: Английский

Serum Proteomics Analysis of Patients with Ascending Aortic Dilation

Cardiovascular Toxicology, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский